15-delta prostaglandin J2-5228 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the 15-delta prostaglandin J2-5228 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD3 abhydrolase domain containing 3
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
ARTN artemin
ATF3 activating transcription factor 3
BIN1 bridging integrator 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C8ORF44 chromosome 8 open reading frame 44
CBR3 carbonyl reductase 3
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CREM cAMP responsive element modulator
CRY2 cryptochrome circadian clock 2
CSRP2 cysteine and glycine-rich protein 2
CTSZ cathepsin Z
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DSTYK dual serine/threonine and tyrosine protein kinase
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FADS2 fatty acid desaturase 2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FECH ferrochelatase
FGFR1 fibroblast growth factor receptor 1
FOSL1 FOS-like antigen 1
FXR2 fragile X mental retardation, autosomal homolog 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLM glutamate-cysteine ligase, modifier subunit
GPR143 G protein-coupled receptor 143
GPX2 glutathione peroxidase 2
HBEGF heparin-binding EGF-like growth factor
HMHA1 histocompatibility (minor) HA-1
HMOX1 heme oxygenase 1
HPN hepsin
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IDS iduronate 2-sulfatase
IFNW1 interferon, omega 1
IGLJ3 immunoglobulin lambda joining 3
IL15RA interleukin 15 receptor, alpha
IL6R interleukin 6 receptor
INHBE inhibin, beta E
LIMK1 LIM domain kinase 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAN1A2 mannosidase, alpha, class 1A, member 2
MAP1B microtubule-associated protein 1B
MAP2K5 mitogen-activated protein kinase kinase 5
MBNL2 muscleblind-like splicing regulator 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIR22HG MIR22 host gene
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NDRG1 N-myc downstream regulated 1
NME5 NME/NM23 family member 5
NMT1 N-myristoyltransferase 1
NPR3 natriuretic peptide receptor 3
NUPR1 nuclear protein, transcriptional regulator, 1
ORAI2 ORAI calcium release-activated calcium modulator 2
OSGIN1 oxidative stress induced growth inhibitor 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLCD1 phospholipase C, delta 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNA3 plexin A3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POFUT1 protein O-fucosyltransferase 1
PPP5C protein phosphatase 5, catalytic subunit
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RB1CC1 RB1-inducible coiled-coil 1
RIOK3 RIO kinase 3
RIT1 Ras-like without CAAX 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SCG2 secretogranin II
SLC16A4 solute carrier family 16, member 4
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
STYK1 serine/threonine/tyrosine kinase 1
TES testin LIM domain protein
TRIM16 tripartite motif containing 16
TSPAN9 tetraspanin 9
TTC38 tetratricopeptide repeat domain 38
TTLL7 tubulin tyrosine ligase-like family member 7
TUBA4A tubulin, alpha 4a
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VLDLR very low density lipoprotein receptor
ZNF226 zinc finger protein 226
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ARRB1 arrestin, beta 1
ARSB arylsulfatase B
ATAD3A ATPase family, AAA domain containing 3A
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BACE1 beta-site APP-cleaving enzyme 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP4 bone morphogenetic protein 4
CCDC9 coiled-coil domain containing 9
CENPO centromere protein O
CHPF chondroitin polymerizing factor
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLCN6 chloride channel, voltage-sensitive 6
CLSPN claspin
CORO1A coronin, actin binding protein, 1A
CPTP ceramide-1-phosphate transfer protein
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
E2F8 E2F transcription factor 8
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
FAM110B family with sequence similarity 110, member B
FAM131A family with sequence similarity 131, member A
FBXO31 F-box protein 31
FCHO1 FCH domain only 1
FUZ fuzzy planar cell polarity protein
GPR19 G protein-coupled receptor 19
GSTTP1 glutathione S-transferase theta pseudogene 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HDAC5 histone deacetylase 5
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL4R interleukin 4 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INF2 inverted formin, FH2 and WH2 domain containing
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA0125 KIAA0125
KIF13B kinesin family member 13B
KIFC1 kinesin family member C1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIME1 Lck interacting transmembrane adaptor 1
LOC257152 uncharacterized LOC257152
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MVP major vault protein
MXD3 MAX dimerization protein 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NCAM2 neural cell adhesion molecule 2
NOL12 nucleolar protein 12
NPTX1 neuronal pentraxin I
OVGP1 oviductal glycoprotein 1, 120kDa
PLD2 phospholipase D2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRMT7 protein arginine methyltransferase 7
RAB3A RAB3A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS19 regulator of G-protein signaling 19
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN2 Ras and Rab interactor 2
RNF43 ring finger protein 43
RWDD2A RWD domain containing 2A
SEPP1 selenoprotein P, plasma, 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC41A3 solute carrier family 41, member 3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLIT2 slit homolog 2 (Drosophila)
SLMO1 slowmo homolog 1 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
SREBF1 sterol regulatory element binding transcription factor 1
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD5 StAR-related lipid transfer (START) domain containing 5
SUN2 Sad1 and UNC84 domain containing 2
TCHH trichohyalin
TMC5 transmembrane channel-like 5
TMEM121 transmembrane protein 121
TMEM132A transmembrane protein 132A
TMEM180 transmembrane protein 180
TMEM212 transmembrane protein 212
TRIM45 tripartite motif containing 45
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSSC4 tumor suppressing subtransferable candidate 4
TUBA3C tubulin, alpha 3c
ZBTB44 zinc finger and BTB domain containing 44
ZNF205 zinc finger protein 205
ZNF551 zinc finger protein 551
ZNF571 zinc finger protein 571
ZNF639 zinc finger protein 639
ZNF747 zinc finger protein 747