15-delta prostaglandin J2-446 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 15-delta prostaglandin J2-446 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ANGPTL4 angiopoietin-like 4
ANKRD40 ankyrin repeat domain 40
APC adenomatous polyposis coli
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
BLMH bleomycin hydrolase
BMP7 bone morphogenetic protein 7
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BTN2A1 butyrophilin, subfamily 2, member A1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CHRM4 cholinergic receptor, muscarinic 4
CLUAP1 clusterin associated protein 1
CNOT4 CCR4-NOT transcription complex, subunit 4
DGCR8 DGCR8 microprocessor complex subunit
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
E2F6 E2F transcription factor 6
FA2H fatty acid 2-hydroxylase
FABP4 fatty acid binding protein 4, adipocyte
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FTCD formimidoyltransferase cyclodeaminase
GAS7 growth arrest-specific 7
GCLM glutamate-cysteine ligase, modifier subunit
GDF11 growth differentiation factor 11
GPC1 glypican 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRIP2 glutamate receptor interacting protein 2
GSK3A glycogen synthase kinase 3 alpha
H2AFY2 H2A histone family, member Y2
HFE hemochromatosis
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPH1 heat shock 105kDa/110kDa protein 1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFFO1 intermediate filament family orphan 1
IGHMBP2 immunoglobulin mu binding protein 2
IRS2 insulin receptor substrate 2
ITGB5 integrin, beta 5
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KLF15 Kruppel-like factor 15
KRT6B keratin 6B, type II
LPIN1 lipin 1
LRRC1 leucine rich repeat containing 1
MBOAT7 membrane bound O-acyltransferase domain containing 7
MCM5 minichromosome maintenance complex component 5
MGA MGA, MAX dimerization protein
MKRN2 makorin ring finger protein 2
MOGAT2 monoacylglycerol O-acyltransferase 2
MST1 macrophage stimulating 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NIPAL2 NIPA-like domain containing 2
NIPAL3 NIPA-like domain containing 3
NMT1 N-myristoyltransferase 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PAIP2B poly(A) binding protein interacting protein 2B
PAX1 paired box 1
PBX2 pre-B-cell leukemia homeobox 2
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLIN2 perilipin 2
PRB1 proline-rich protein BstNI subfamily 1
PRKCD protein kinase C, delta
PRRC2B proline-rich coiled-coil 2B
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RARG retinoic acid receptor, gamma
RB1CC1 RB1-inducible coiled-coil 1
RBL2 retinoblastoma-like 2
RREB1 ras responsive element binding protein 1
SIDT2 SID1 transmembrane family, member 2
SIM2 single-minded family bHLH transcription factor 2
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SNPH syntaphilin
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
STXBP5L syntaxin binding protein 5-like
TCEA2 transcription elongation factor A (SII), 2
TET3 tet methylcytosine dioxygenase 3
TFCP2 transcription factor CP2
TNK1 tyrosine kinase, non-receptor, 1
TRIM16 tripartite motif containing 16
VAC14 Vac14 homolog (S. cerevisiae)
WDR46 WD repeat domain 46
WTAP Wilms tumor 1 associated protein
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF131 zinc finger protein 131
ZNF43 zinc finger protein 43
ZNF507 zinc finger protein 507

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABI3BP ABI family, member 3 (NESH) binding protein
ACBD4 acyl-CoA binding domain containing 4
ADGRG6 adhesion G protein-coupled receptor G6
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ATF7IP2 activating transcription factor 7 interacting protein 2
BEST2 bestrophin 2
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C19ORF57 chromosome 19 open reading frame 57
C2CD5 C2 calcium-dependent domain containing 5
C5 complement component 5
C9ORF3 chromosome 9 open reading frame 3
CD300C CD300c molecule
CD8A CD8a molecule
CDC45 cell division cycle 45
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CKAP2 cytoskeleton associated protein 2
CLDN11 claudin 11
CLDN14 claudin 14
COL5A2 collagen, type V, alpha 2
CORO2A coronin, actin binding protein, 2A
CSN2 casein beta
CTGF connective tissue growth factor
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ERMP1 endoplasmic reticulum metallopeptidase 1
ESM1 endothelial cell-specific molecule 1
FGF13 fibroblast growth factor 13
FKBPL FK506 binding protein like
FZD8 frizzled class receptor 8
GUSBP3 glucuronidase, beta pseudogene 3
H1FX H1 histone family, member X
HAS2 hyaluronan synthase 2
HINFP histone H4 transcription factor
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HPSE heparanase
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IKZF4 IKAROS family zinc finger 4 (Eos)
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KIF16B kinesin family member 16B
KIF3A kinesin family member 3A
KIFAP3 kinesin-associated protein 3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KRT15 keratin 15, type I
LDHC lactate dehydrogenase C
LIN7B lin-7 homolog B (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LMO3 LIM domain only 3 (rhombotin-like 2)
LYRM2 LYR motif containing 2
MYL1 myosin, light chain 1, alkali; skeletal, fast
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NPY1R neuropeptide Y receptor Y1
NVL nuclear VCP-like
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAQR6 progestin and adipoQ receptor family member VI
PC pyruvate carboxylase
PCSK7 proprotein convertase subtilisin/kexin type 7
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PFAS phosphoribosylformylglycinamidine synthase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAU plasminogen activator, urokinase
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLK2 polo-like kinase 2
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPAP2B phosphatidic acid phosphatase type 2B
PPARG peroxisome proliferator-activated receptor gamma
PTX3 pentraxin 3, long
RAB33B RAB33B, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RGS2 regulator of G-protein signaling 2
RIPPLY3 ripply transcriptional repressor 3
RNPEP arginyl aminopeptidase (aminopeptidase B)
SDC3 syndecan 3
SLC17A4 solute carrier family 17, member 4
SLC22A18 solute carrier family 22, member 18
SPDL1 spindle apparatus coiled-coil protein 1
STX5 syntaxin 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYT2 synaptotagmin II
TBPL1 TBP-like 1
TEX40 testis expressed 40
THBS2 thrombospondin 2
TMC7 transmembrane channel-like 7
TNS4 tensin 4
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VASP vasodilator-stimulated phosphoprotein
WNT7A wingless-type MMTV integration site family, member 7A
XAB2 XPA binding protein 2
ZBTB16 zinc finger and BTB domain containing 16
ZFR2 zinc finger RNA binding protein 2
ZMAT5 zinc finger, matrin-type 5
ZNF32 zinc finger protein 32