15-delta prostaglandin J2-2691 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 15-delta prostaglandin J2-2691 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
ANXA2P2 annexin A2 pseudogene 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAG3 BCL2-associated athanogene 3
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C18ORF25 chromosome 18 open reading frame 25
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLGN calmegin
CREM cAMP responsive element modulator
CSRP2 cysteine and glycine-rich protein 2
CXCL2 chemokine (C-X-C motif) ligand 2
DDIT3 DNA-damage-inducible transcript 3
DGKG diacylglycerol kinase, gamma 90kDa
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EFNB2 ephrin-B2
EIF5 eukaryotic translation initiation factor 5
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPS8 epidermal growth factor receptor pathway substrate 8
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
FZD3 frizzled class receptor 3
GABARAPL1 GABA(A) receptor-associated protein like 1
GCH1 GTP cyclohydrolase 1
GCLM glutamate-cysteine ligase, modifier subunit
H2BFS H2B histone family, member S (pseudogene)
HES1 hes family bHLH transcription factor 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2AE histone cluster 1, H2ae
HIST1H2AM histone cluster 1, H2am
HIST1H2BG histone cluster 1, H2bg
HIST1H3H histone cluster 1, H3h
HIST1H3J histone cluster 1, H3j
HIST1H4A histone cluster 1, H4a
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HOXA9 homeobox A9
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER5 immediate early response 5
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MARCKS myristoylated alanine-rich protein kinase C substrate
MBNL2 muscleblind-like splicing regulator 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIR22HG MIR22 host gene
N4BP2L2 NEDD4 binding protein 2-like 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NUPR1 nuclear protein, transcriptional regulator, 1
OSGIN1 oxidative stress induced growth inhibitor 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCDH9 protocadherin 9
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGA8 protocadherin gamma subfamily A, 8
PDE4DIP phosphodiesterase 4D interacting protein
PIR pirin (iron-binding nuclear protein)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POPDC3 popeye domain containing 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RFPL3S RFPL3 antisense
RHBDD3 rhomboid domain containing 3
RHOB ras homolog family member B
RIT1 Ras-like without CAAX 1
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPATS2L spermatogenesis associated, serine-rich 2-like
SQSTM1 sequestosome 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPST1 tyrosylprotein sulfotransferase 1
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
TXNRD1 thioredoxin reductase 1
ULBP2 UL16 binding protein 2
ZBTB38 zinc finger and BTB domain containing 38
ZNF222 zinc finger protein 222
ZNF235 zinc finger protein 235
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AEN apoptosis enhancing nuclease
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ATP8B4 ATPase, class I, type 8B, member 4
BAHCC1 BAH domain and coiled-coil containing 1
BTF3P12 basic transcription factor 3 pseudogene 12
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C14ORF159 chromosome 14 open reading frame 159
C7ORF69 chromosome 7 open reading frame 69
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCL2 chemokine (C-C motif) ligand 2
CCR2 chemokine (C-C motif) receptor 2
CD3EAP CD3e molecule, epsilon associated protein
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CHMP1A charged multivesicular body protein 1A
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CIDEB cell death-inducing DFFA-like effector b
CLEC2D C-type lectin domain family 2, member D
CLTCL1 clathrin, heavy chain-like 1
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CPTP ceramide-1-phosphate transfer protein
DDHD2 DDHD domain containing 2
DDN dendrin
DPY19L2P2 DPY19L2 pseudogene 2
EFCAB2 EF-hand calcium binding domain 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FJX1 four jointed box 1 (Drosophila)
FLT3 fms-related tyrosine kinase 3
FRS3 fibroblast growth factor receptor substrate 3
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GFI1 growth factor independent 1 transcription repressor
GRAMD4 GRAM domain containing 4
GRWD1 glutamate-rich WD repeat containing 1
HEATR3 HEAT repeat containing 3
HK2 hexokinase 2
HYAL3 hyaluronoglucosaminidase 3
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIAA0930 KIAA0930
KLF13 Kruppel-like factor 13
KRI1 KRI1 homolog (S. cerevisiae)
LTB lymphotoxin beta (TNF superfamily, member 3)
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
METTL1 methyltransferase like 1
MNT MAX network transcriptional repressor
MOGS mannosyl-oligosaccharide glucosidase
MRPS18C mitochondrial ribosomal protein S18C
MTSS1L metastasis suppressor 1-like
MXD3 MAX dimerization protein 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFE2 nuclear factor, erythroid 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PALB2 partner and localizer of BRCA2
PAQR4 progestin and adipoQ receptor family member IV
PARP16 poly (ADP-ribose) polymerase family, member 16
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PGP phosphoglycolate phosphatase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PMCH pro-melanin-concentrating hormone
PRKCZ protein kinase C, zeta
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGS19 regulator of G-protein signaling 19
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPUSD2 RNA pseudouridylate synthase domain containing 2
SIPA1 signal-induced proliferation-associated 1
SIX3 SIX homeobox 3
SLA Src-like-adaptor
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TGM5 transglutaminase 5
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TLR8 toll-like receptor 8
TMEM104 transmembrane protein 104
TMEM212 transmembrane protein 212
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRAC T cell receptor alpha constant
TRIM66 tripartite motif containing 66
TRIM8 tripartite motif containing 8
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UCN urocortin
UNG uracil-DNA glycosylase
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
WT1 Wilms tumor 1
WT1-AS WT1 antisense RNA
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YY2 YY2 transcription factor
ZBED8 zinc finger, BED-type containing 8
ZNF74 zinc finger protein 74
ZNF747 zinc finger protein 747