15-delta prostaglandin J2-1656 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 15-delta prostaglandin J2-1656 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD11 ankyrin repeat domain 11
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
ASF1A anti-silencing function 1A histone chaperone
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BAX BCL2-associated X protein
BIN1 bridging integrator 1
C2ORF27A chromosome 2 open reading frame 27A
CBR3 carbonyl reductase 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CREM cAMP responsive element modulator
CSRP2 cysteine and glycine-rich protein 2
CTH cystathionine gamma-lyase
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP1 dual specificity phosphatase 1
EML2 echinoderm microtubule associated protein like 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FOSL1 FOS-like antigen 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GPX3 glutathione peroxidase 3
GRB10 growth factor receptor-bound protein 10
HIRA histone cell cycle regulator
HLA-G major histocompatibility complex, class I, G
HMHA1 histocompatibility (minor) HA-1
HMOX1 heme oxygenase 1
HOMER3 homer scaffolding protein 3
HSPA1A heat shock 70kDa protein 1A
HSPA1L heat shock 70kDa protein 1-like
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IFRD1 interferon-related developmental regulator 1
INHBE inhibin, beta E
JUN jun proto-oncogene
LARP6 La ribonucleoprotein domain family, member 6
LDLR low density lipoprotein receptor
LGALS8 lectin, galactoside-binding, soluble, 8
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP1B microtubule-associated protein 1B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIR22HG MIR22 host gene
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NAP1L2 nucleosome assembly protein 1-like 2
NDRG1 N-myc downstream regulated 1
OSGIN1 oxidative stress induced growth inhibitor 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PELO pelota homolog (Drosophila)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
RGCC regulator of cell cycle
RIT1 Ras-like without CAAX 1
RPL7 ribosomal protein L7
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3BGR SH3 domain binding glutamate-rich protein
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
STYK1 serine/threonine/tyrosine kinase 1
TES testin LIM domain protein
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIB3 tribbles pseudokinase 3
TUBA4A tubulin, alpha 4a
TXNRD1 thioredoxin reductase 1
UBB ubiquitin B
ULBP2 UL16 binding protein 2
UNKL unkempt family zinc finger-like
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
ZNF227 zinc finger protein 227
ZNF329 zinc finger protein 329
ZNF350 zinc finger protein 350
ZNF365 zinc finger protein 365

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AKAP12 A kinase (PRKA) anchor protein 12
ANKRD36B ankyrin repeat domain 36B
ARMC6 armadillo repeat containing 6
AURKB aurora kinase B
BAMBI BMP and activin membrane-bound inhibitor
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2L2 BCL2-like 2
BCOR BCL6 corepressor
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF68 chromosome 11 open reading frame 68
C19ORF40 chromosome 19 open reading frame 40
C6ORF47 chromosome 6 open reading frame 47
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCNO cyclin O
CDC20 cell division cycle 20
CLDN9 claudin 9
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CXCL12 chemokine (C-X-C motif) ligand 12
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
DKK1 dickkopf WNT signaling pathway inhibitor 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
E2F1 E2F transcription factor 1
E2F8 E2F transcription factor 8
EFNA1 ephrin-A1
ELOVL4 ELOVL fatty acid elongase 4
EVL Enah/Vasp-like
FAM111A family with sequence similarity 111, member A
FBXO5 F-box protein 5
FKBP10 FK506 binding protein 10, 65 kDa
GALE UDP-galactose-4-epimerase
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
GTF2I general transcription factor IIi
H2AFJ H2A histone family, member J
HILPDA hypoxia inducible lipid droplet-associated
HIST1H2AJ histone cluster 1, H2aj
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
INF2 inverted formin, FH2 and WH2 domain containing
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0125 KIAA0125
KIF18A kinesin family member 18A
KIF23 kinesin family member 23
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC20 leucine rich repeat containing 20
MAGEF1 melanoma antigen family F1
MEIS1 Meis homeobox 1
METTL8 methyltransferase like 8
MOGS mannosyl-oligosaccharide glucosidase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NDE1 nudE neurodevelopment protein 1
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUP62CL nucleoporin 62kDa C-terminal like
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAQR4 progestin and adipoQ receptor family member IV
PAQR6 progestin and adipoQ receptor family member VI
PARD6A par-6 family cell polarity regulator alpha
PDZK1 PDZ domain containing 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRKCD protein kinase C, delta
PRR15L proline rich 15-like
PSRC1 proline/serine-rich coiled-coil 1
PTK6 protein tyrosine kinase 6
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPRU protein tyrosine phosphatase, receptor type, U
RAB5B RAB5B, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RECQL4 RecQ protein-like 4
RGS16 regulator of G-protein signaling 16
RHOBTB1 Rho-related BTB domain containing 1
RIPPLY3 ripply transcriptional repressor 3
SALL2 spalt-like transcription factor 2
SETD6 SET domain containing 6
SHPK sedoheptulokinase
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SPC25 SPC25, NDC80 kinetochore complex component
SYTL2 synaptotagmin-like 2
TCEAL1 transcription elongation factor A (SII)-like 1
TGFB3 transforming growth factor, beta 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TRIM45 tripartite motif containing 45
TRPS1 trichorhinophalangeal syndrome I
UNC119 unc-119 homolog (C. elegans)
USP18 ubiquitin specific peptidase 18
XYLT2 xylosyltransferase II
ZNF205 zinc finger protein 205
ZNF250 zinc finger protein 250
ZNF672 zinc finger protein 672
ZNF816 zinc finger protein 816
ZXDC ZXD family zinc finger C