15-delta prostaglandin J2-1231 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 15-delta prostaglandin J2-1231 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADM adrenomedullin
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANGPTL4 angiopoietin-like 4
AQP3 aquaporin 3 (Gill blood group)
BAG3 BCL2-associated athanogene 3
BAMBI BMP and activin membrane-bound inhibitor
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BTBD7 BTB (POZ) domain containing 7
C18ORF25 chromosome 18 open reading frame 25
CDH7 cadherin 7, type 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLK1 CDC-like kinase 1
CLU clusterin
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRY2 cryptochrome circadian clock 2
CRYAB crystallin, alpha B
CTGF connective tissue growth factor
DDIT4 DNA-damage-inducible transcript 4
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
FABP4 fatty acid binding protein 4, adipocyte
FKBP4 FK506 binding protein 4, 59kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
FYB FYN binding protein
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GAREM GRB2 associated, regulator of MAPK1
GCLM glutamate-cysteine ligase, modifier subunit
GLA galactosidase, alpha
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA1L heat shock 70kDa protein 1-like
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPB8 heat shock 22kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IL12A interleukin 12A
IL7R interleukin 7 receptor
JUN jun proto-oncogene
KDM2A lysine (K)-specific demethylase 2A
KLHL21 kelch-like family member 21
LDLR low density lipoprotein receptor
LPIN1 lipin 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MIR22HG MIR22 host gene
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MSX1 msh homeobox 1
NMT1 N-myristoyltransferase 1
OSGIN1 oxidative stress induced growth inhibitor 1
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PGF placental growth factor
PLIN2 perilipin 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RGS14 regulator of G-protein signaling 14
RHOB ras homolog family member B
RND1 Rho family GTPase 1
RNF19B ring finger protein 19B
RNF216 ring finger protein 216
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RSAD2 radical S-adenosyl methionine domain containing 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SIX1 SIX homeobox 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
STK17B serine/threonine kinase 17b
SWAP70 SWAP switching B-cell complex 70kDa subunit
TRIM16 tripartite motif containing 16
TRIM2 tripartite motif containing 2
TRIM26 tripartite motif containing 26
TSPYL2 TSPY-like 2
TXNRD1 thioredoxin reductase 1
UBB ubiquitin B
UGT8 UDP glycosyltransferase 8
USPL1 ubiquitin specific peptidase like 1
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
AFAP1 actin filament associated protein 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID5B AT rich interactive domain 5B (MRF1-like)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL2A1 BCL2-related protein A1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BMP2 bone morphogenetic protein 2
BOLA1 bolA family member 1
BORA bora, aurora kinase A activator
C11ORF68 chromosome 11 open reading frame 68
C19ORF24 chromosome 19 open reading frame 24
C6ORF47 chromosome 6 open reading frame 47
CBX7 chromobox homolog 7
CBY1 chibby homolog 1 (Drosophila)
CENPC centromere protein C
COL5A2 collagen, type V, alpha 2
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DEPDC1 DEP domain containing 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP4 dual specificity phosphatase 4
E2F8 E2F transcription factor 8
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPN3 epsin 3
FANCF Fanconi anemia, complementation group F
FZD8 frizzled class receptor 8
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GPRIN2 G protein regulated inducer of neurite outgrowth 2
H1F0 H1 histone family, member 0
HAS2 hyaluronan synthase 2
HIST1H1D histone cluster 1, H1d
HMGA2 high mobility group AT-hook 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL10RB interleukin 10 receptor, beta
IL33 interleukin 33
INHBB inhibin, beta B
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRS1 insulin receptor substrate 1
KIF15 kinesin family member 15
KIF20A kinesin family member 20A
KIFC1 kinesin family member C1
LIF leukemia inhibitory factor
LMNB1 lamin B1
LOC100127972 uncharacterized LOC100127972
LPAR6 lysophosphatidic acid receptor 6
LYPLA2P1 lysophospholipase II pseudogene 1
LZTR1 leucine-zipper-like transcription regulator 1
MAGEF1 melanoma antigen family F1
MALL mal, T-cell differentiation protein-like
MANEA mannosidase, endo-alpha
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
NAP1L3 nucleosome assembly protein 1-like 3
NEK2 NIMA-related kinase 2
NHLRC2 NHL repeat containing 2
NOL12 nucleolar protein 12
OLFML3 olfactomedin-like 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PALMD palmdelphin
PARD6A par-6 family cell polarity regulator alpha
PC pyruvate carboxylase
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEX11B peroxisomal biogenesis factor 11 beta
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLM polymerase (DNA directed), mu
PPAP2B phosphatidic acid phosphatase type 2B
PPARG peroxisome proliferator-activated receptor gamma
PQLC1 PQ loop repeat containing 1
PRR15L proline rich 15-like
PSRC1 proline/serine-rich coiled-coil 1
PTGFR prostaglandin F receptor (FP)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PYCRL pyrroline-5-carboxylate reductase-like
RCOR3 REST corepressor 3
RGS2 regulator of G-protein signaling 2
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SCG5 secretogranin V
SIGLEC15 sialic acid binding Ig-like lectin 15
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST5 suppression of tumorigenicity 5
SYTL2 synaptotagmin-like 2
THBS3 thrombospondin 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TOP2A topoisomerase (DNA) II alpha 170kDa
TRIM66 tripartite motif containing 66
TRIOBP TRIO and F-actin binding protein
TUBA3C tubulin, alpha 3c
WDR5B WD repeat domain 5B
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF248 zinc finger protein 248
ZNF629 zinc finger protein 629
ZNF696 zinc finger protein 696
ZNF84 zinc finger protein 84