15-delta prostaglandin J2-1172 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 15-delta prostaglandin J2-1172 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ANXA2 annexin A2
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APOC1 apolipoprotein C-I
APOL2 apolipoprotein L, 2
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATRX alpha thalassemia/mental retardation syndrome X-linked
BAG3 BCL2-associated athanogene 3
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C18ORF25 chromosome 18 open reading frame 25
C9ORF9 chromosome 9 open reading frame 9
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCPG1 cell cycle progression 1
CD84 CD84 molecule
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CREM cAMP responsive element modulator
CSNK1E casein kinase 1, epsilon
CTH cystathionine gamma-lyase
CXCL2 chemokine (C-X-C motif) ligand 2
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DOHH deoxyhypusine hydroxylase/monooxygenase
EIF5 eukaryotic translation initiation factor 5
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EWSR1 EWS RNA-binding protein 1
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GABARAPL1 GABA(A) receptor-associated protein like 1
GCLM glutamate-cysteine ligase, modifier subunit
GDAP1 ganglioside induced differentiation associated protein 1
GSR glutathione reductase
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IL27RA interleukin 27 receptor, alpha
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCTD20 potassium channel tetramerization domain containing 20
KIAA0753 KIAA0753
KLF6 Kruppel-like factor 6
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL2 muscleblind-like splicing regulator 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED20 mediator complex subunit 20
MIR22HG MIR22 host gene
MOB3B MOB kinase activator 3B
MYO10 myosin X
MYO1B myosin IB
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
NSFL1C NSFL1 (p97) cofactor (p47)
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OSER1 oxidative stress responsive serine-rich 1
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PGD phosphogluconate dehydrogenase
PGM3 phosphoglucomutase 3
PHTF1 putative homeodomain transcription factor 1
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIR pirin (iron-binding nuclear protein)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PPID peptidylprolyl isomerase D
PSAT1 phosphoserine aminotransferase 1
RIT1 Ras-like without CAAX 1
RNF6 ring finger protein (C3H2C3 type) 6
SEC24D SEC24 family member D
SENP5 SUMO1/sentrin specific peptidase 5
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC39A9 solute carrier family 39, member 9
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
STIP1 stress-induced phosphoprotein 1
STK17A serine/threonine kinase 17a
STX5 syntaxin 5
TFEC transcription factor EC
TRAFD1 TRAF-type zinc finger domain containing 1
TSPYL2 TSPY-like 2
TUBB2A tubulin, beta 2A class IIa
TWF1 twinfilin actin binding protein 1
TXNRD1 thioredoxin reductase 1
UBB ubiquitin B
UNKL unkempt family zinc finger-like
VAC14 Vac14 homolog (S. cerevisiae)
ZBTB39 zinc finger and BTB domain containing 39
ZNF211 zinc finger protein 211
ZNF222 zinc finger protein 222
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ANKRD36 ankyrin repeat domain 36
ANKRD55 ankyrin repeat domain 55
ANP32A-IT1 ANP32A intronic transcript 1
ARHGAP4 Rho GTPase activating protein 4
ARID5B AT rich interactive domain 5B (MRF1-like)
ASTE1 asteroid homolog 1 (Drosophila)
AURKB aurora kinase B
BBS10 Bardet-Biedl syndrome 10
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCOR BCL6 corepressor
C10ORF2 chromosome 10 open reading frame 2
C11ORF21 chromosome 11 open reading frame 21
C16ORF59 chromosome 16 open reading frame 59
C1ORF106 chromosome 1 open reading frame 106
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCDC86 coiled-coil domain containing 86
CCL2 chemokine (C-C motif) ligand 2
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD1D CD1d molecule
CD3EAP CD3e molecule, epsilon associated protein
CD69 CD69 molecule
CGREF1 cell growth regulator with EF-hand domain 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLDN15 claudin 15
CLSPN claspin
CLTCL1 clathrin, heavy chain-like 1
CORO7 coronin 7
CXORF56 chromosome X open reading frame 56
DIXDC1 DIX domain containing 1
EGR2 early growth response 2
ENDOG endonuclease G
EXOSC5 exosome component 5
FAM173A family with sequence similarity 173, member A
GFI1 growth factor independent 1 transcription repressor
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GRAMD1B GRAM domain containing 1B
GTPBP6 GTP binding protein 6 (putative)
HDAC5 histone deacetylase 5
HIRA histone cell cycle regulator
HLX H2.0-like homeobox
IFI6 interferon, alpha-inducible protein 6
IL4R interleukin 4 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IPO4 importin 4
IRF8 interferon regulatory factor 8
KIAA0930 KIAA0930
KLF13 Kruppel-like factor 13
LAMP5 lysosomal-associated membrane protein family, member 5
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LPCAT1 lysophosphatidylcholine acyltransferase 1
MAGEF1 melanoma antigen family F1
MBTD1 mbt domain containing 1
MCM3AP-AS1 MCM3AP antisense RNA 1
METTL8 methyltransferase like 8
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYC v-myc avian myelocytomatosis viral oncogene homolog
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NFE2 nuclear factor, erythroid 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
PFAS phosphoribosylformylglycinamidine synthase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRTN3 proteinase 3
PSRC1 proline/serine-rich coiled-coil 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PUS7 pseudouridylate synthase 7 (putative)
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RFWD3 ring finger and WD repeat domain 3
RGS19 regulator of G-protein signaling 19
RNF144A ring finger protein 144A
RNF44 ring finger protein 44
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RSAD1 radical S-adenosyl methionine domain containing 1
SDCCAG3 serologically defined colon cancer antigen 3
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STX10 syntaxin 10
SUN2 Sad1 and UNC84 domain containing 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TERT telomerase reverse transcriptase
THBS4 thrombospondin 4
TMC6 transmembrane channel-like 6
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UBQLN4 ubiquilin 4
UPB1 ureidopropionase, beta
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
WDR3 WD repeat domain 3
WT1-AS WT1 antisense RNA
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF248 zinc finger protein 248