15-delta prostaglandin J2-1069 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 15-delta prostaglandin J2-1069 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD11 ankyrin repeat domain 11
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BANP BTG3 associated nuclear protein
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
CARS cysteinyl-tRNA synthetase
CBR3 carbonyl reductase 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLK1 CDC-like kinase 1
CREM cAMP responsive element modulator
CSRP2 cysteine and glycine-rich protein 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM188A family with sequence similarity 188, member A
FAM49B family with sequence similarity 49, member B
FAS Fas cell surface death receptor
FOSL1 FOS-like antigen 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLM glutamate-cysteine ligase, modifier subunit
GEM GTP binding protein overexpressed in skeletal muscle
GPX3 glutathione peroxidase 3
GRB10 growth factor receptor-bound protein 10
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA1L heat shock 70kDa protein 1-like
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
IL15RA interleukin 15 receptor, alpha
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
LGALS8 lectin, galactoside-binding, soluble, 8
LPIN1 lipin 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP1B microtubule-associated protein 1B
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL5 methyltransferase like 5
MIR22HG MIR22 host gene
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MOCOS molybdenum cofactor sulfurase
MORC4 MORC family CW-type zinc finger 4
MRPL18 mitochondrial ribosomal protein L18
MSX1 msh homeobox 1
NAP1L2 nucleosome assembly protein 1-like 2
NDRG1 N-myc downstream regulated 1
NFIL3 nuclear factor, interleukin 3 regulated
OSBP oxysterol binding protein
OSGIN1 oxidative stress induced growth inhibitor 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3BGR SH3 domain binding glutamate-rich protein
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STK17A serine/threonine kinase 17a
TES testin LIM domain protein
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIB3 tribbles pseudokinase 3
TSPYL2 TSPY-like 2
TUBA4A tubulin, alpha 4a
TXNL4B thioredoxin-like 4B
TXNRD1 thioredoxin reductase 1
VEGFA vascular endothelial growth factor A
ZFAND5 zinc finger, AN1-type domain 5
ZNF227 zinc finger protein 227
ZNF473 zinc finger protein 473

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AMIGO2 adhesion molecule with Ig-like domain 2
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARID5B AT rich interactive domain 5B (MRF1-like)
ARRB2 arrestin, beta 2
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
B3GNT1
BAMBI BMP and activin membrane-bound inhibitor
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
CCDC15 coiled-coil domain containing 15
CCNE2 cyclin E2
CCNL2 cyclin L2
CSAD cysteine sulfinic acid decarboxylase
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CXCL12 chemokine (C-X-C motif) ligand 12
DDHD2 DDHD domain containing 2
DHRS1 dehydrogenase/reductase (SDR family) member 1
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNA2 DNA replication helicase/nuclease 2
DSN1 DSN1, MIS12 kinetochore complex component
E2F8 E2F transcription factor 8
EFNA1 ephrin-A1
EGR3 early growth response 3
EPHA4 EPH receptor A4
EPS8L2 EPS8-like 2
ERCC6L excision repair cross-complementation group 6-like
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FANCL Fanconi anemia, complementation group L
FBXO5 F-box protein 5
FCHSD2 FCH and double SH3 domains 2
FPGT fucose-1-phosphate guanylyltransferase
GCA grancalcin, EF-hand calcium binding protein
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
GTPBP3 GTP binding protein 3 (mitochondrial)
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB3 high mobility group box 3
HOXC11 homeobox C11
HOXC6 homeobox C6
HYAL2 hyaluronoglucosaminidase 2
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGFLR1 IGF-like family receptor 1
IPP intracisternal A particle-promoted polypeptide
LIMA1 LIM domain and actin binding 1
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP6D1 MAP6 domain containing 1
MNX1 motor neuron and pancreas homeobox 1
MOGS mannosyl-oligosaccharide glucosidase
MRPL34 mitochondrial ribosomal protein L34
MSL1 male-specific lethal 1 homolog (Drosophila)
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NPY1R neuropeptide Y receptor Y1
OPHN1 oligophrenin 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PBLD phenazine biosynthesis-like protein domain containing
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRR15L proline rich 15-like
PSRC1 proline/serine-rich coiled-coil 1
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RGS16 regulator of G-protein signaling 16
RIPPLY3 ripply transcriptional repressor 3
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RPUSD2 RNA pseudouridylate synthase domain containing 2
RWDD2A RWD domain containing 2A
SCO2 SCO2 cytochrome c oxidase assembly protein
SECISBP2 SECIS binding protein 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SETD6 SET domain containing 6
SHPK sedoheptulokinase
SLC35E3 solute carrier family 35, member E3
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SNRPF small nuclear ribonucleoprotein polypeptide F
SUOX sulfite oxidase
SUSD4 sushi domain containing 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYTL2 synaptotagmin-like 2
TBCC tubulin folding cofactor C
TCEAL1 transcription elongation factor A (SII)-like 1
TMEM168 transmembrane protein 168
TMEM223 transmembrane protein 223
TMEM30B transmembrane protein 30B
TPBG trophoblast glycoprotein
TRIM45 tripartite motif containing 45
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
VAV3 vav 3 guanine nucleotide exchange factor
WDR6 WD repeat domain 6
ZBED8 zinc finger, BED-type containing 8
ZFC3H1 zinc finger, C3H1-type containing
ZHX2 zinc fingers and homeoboxes 2
ZMYM3 zinc finger, MYM-type 3
ZNF248 zinc finger protein 248
ZNF512B zinc finger protein 512B
ZNF692 zinc finger protein 692