15-delta prostaglandin J2-1011 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the 15-delta prostaglandin J2-1011 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACVR1B activin A receptor, type IB
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ATF3 activating transcription factor 3
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
CBR3 carbonyl reductase 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2AIP CDKN2A interacting protein
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CREM cAMP responsive element modulator
CSRP2 cysteine and glycine-rich protein 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV5 ets variant 5
F3 coagulation factor III (thromboplastin, tissue factor)
FAM129A family with sequence similarity 129, member A
FAM49B family with sequence similarity 49, member B
FAS Fas cell surface death receptor
FOSL1 FOS-like antigen 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45G growth arrest and DNA-damage-inducible, gamma
GCLM glutamate-cysteine ligase, modifier subunit
GEM GTP binding protein overexpressed in skeletal muscle
GPX2 glutathione peroxidase 2
GPX3 glutathione peroxidase 3
GRB10 growth factor receptor-bound protein 10
HIST1H2BJ histone cluster 1, H2bj
HMOX1 heme oxygenase 1
HSPA12A heat shock 70kDa protein 12A
HSPA1A heat shock 70kDa protein 1A
HSPA1L heat shock 70kDa protein 1-like
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
IL15RA interleukin 15 receptor, alpha
INHBE inhibin, beta E
IQCG IQ motif containing G
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LARP6 La ribonucleoprotein domain family, member 6
LDLR low density lipoprotein receptor
LGALS8 lectin, galactoside-binding, soluble, 8
LPIN1 lipin 1
LRP5L low density lipoprotein receptor-related protein 5-like
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MIR22HG MIR22 host gene
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MSX1 msh homeobox 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDRG1 N-myc downstream regulated 1
NFIL3 nuclear factor, interleukin 3 regulated
OSGIN1 oxidative stress induced growth inhibitor 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARD peroxisome proliferator-activated receptor delta
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RGCC regulator of cell cycle
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3BGR SH3 domain binding glutamate-rich protein
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STYK1 serine/threonine/tyrosine kinase 1
TES testin LIM domain protein
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPP1 tripeptidyl peptidase I
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
TUBA4A tubulin, alpha 4a
UBB ubiquitin B
ULBP2 UL16 binding protein 2
UPP1 uridine phosphorylase 1
VEGFA vascular endothelial growth factor A
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF350 zinc finger protein 350
ZNF365 zinc finger protein 365
ZNF473 zinc finger protein 473

decreased expression

Symbol Name
ANP32A-IT1 ANP32A intronic transcript 1
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMCX1 armadillo repeat containing, X-linked 1
B3GNT1
BAMBI BMP and activin membrane-bound inhibitor
BATF basic leucine zipper transcription factor, ATF-like
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C11ORF68 chromosome 11 open reading frame 68
C9ORF40 chromosome 9 open reading frame 40
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCNE2 cyclin E2
CCNF cyclin F
CCNO cyclin O
CENPC centromere protein C
CLDN9 claudin 9
CRY2 cryptochrome circadian clock 2
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CXCL12 chemokine (C-X-C motif) ligand 12
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DHRS11 dehydrogenase/reductase (SDR family) member 11
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSN1 DSN1, MIS12 kinetochore complex component
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
E2F8 E2F transcription factor 8
EFNA1 ephrin-A1
EGR3 early growth response 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPHA4 EPH receptor A4
EPN3 epsin 3
ERCC6L excision repair cross-complementation group 6-like
FBXO5 F-box protein 5
FEN1 flap structure-specific endonuclease 1
GALK1 galactokinase 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GJA1 gap junction protein, alpha 1, 43kDa
GPR19 G protein-coupled receptor 19
H2AFJ H2A histone family, member J
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HYAL2 hyaluronoglucosaminidase 2
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LINC00339 long intergenic non-protein coding RNA 339
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP1S microtubule-associated protein 1S
MCM10 minichromosome maintenance complex component 10
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
METTL16 methyltransferase like 16
MOGS mannosyl-oligosaccharide glucosidase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
NR2F2 nuclear receptor subfamily 2, group F, member 2
OPN3 opsin 3
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAQR4 progestin and adipoQ receptor family member IV
PCNXL4 pecanex-like 4 (Drosophila)
PEX11A peroxisomal biogenesis factor 11 alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PODXL2 podocalyxin-like 2
PP14571 uncharacterized LOC100130449
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCD protein kinase C, delta
PRMT7 protein arginine methyltransferase 7
PRR15L proline rich 15-like
PSRC1 proline/serine-rich coiled-coil 1
PTTG3P pituitary tumor-transforming 3, pseudogene
PYCRL pyrroline-5-carboxylate reductase-like
RAB26 RAB26, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS16 regulator of G-protein signaling 16
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RLN2 relaxin 2
RWDD2A RWD domain containing 2A
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SNHG3 small nucleolar RNA host gene 3
SULF1 sulfatase 1
SYTL2 synaptotagmin-like 2
TCEAL1 transcription elongation factor A (SII)-like 1
TCTN2 tectonic family member 2
TEAD3 TEA domain family member 3
TGFB3 transforming growth factor, beta 3
TMEM164 transmembrane protein 164
TOE1 target of EGR1, member 1 (nuclear)
TRAPPC11 trafficking protein particle complex 11
UBTF upstream binding transcription factor, RNA polymerase I
ZMYM3 zinc finger, MYM-type 3
ZNF276 zinc finger protein 276
ZNF767P zinc finger family member 767, pseudogene