0316684-0000-7057 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the 0316684-0000-7057 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APP amyloid beta (A4) precursor protein
ATF7IP activating transcription factor 7 interacting protein
ATG3 autophagy related 3
ATXN7 ataxin 7
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BIRC3 baculoviral IAP repeat containing 3
BMP1 bone morphogenetic protein 1
CAPN5 calpain 5
CDK10 cyclin-dependent kinase 10
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CHMP6 charged multivesicular body protein 6
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CNTNAP1 contactin associated protein 1
CPT1A carnitine palmitoyltransferase 1A (liver)
CTSZ cathepsin Z
DBF4B DBF4 zinc finger B
DFNB31 deafness, autosomal recessive 31
DLX2 distal-less homeobox 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EN2 engrailed homeobox 2
ERP44 endoplasmic reticulum protein 44
FABP4 fatty acid binding protein 4, adipocyte
FAM188A family with sequence similarity 188, member A
FAM89B family with sequence similarity 89, member B
FBXL7 F-box and leucine-rich repeat protein 7
FGFR2 fibroblast growth factor receptor 2
GAMT guanidinoacetate N-methyltransferase
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GPER1 G protein-coupled estrogen receptor 1
GSDMB gasdermin B
GSK3A glycogen synthase kinase 3 alpha
HCRP1 hepatocellular carcinoma-related HCRP1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HLA-G major histocompatibility complex, class I, G
HNRNPM heterogeneous nuclear ribonucleoprotein M
IFI16 interferon, gamma-inducible protein 16
ITFG2 integrin alpha FG-GAP repeat containing 2
JAG2 jagged 2
KDM4A lysine (K)-specific demethylase 4A
KIAA1109 KIAA1109
KIF5C kinesin family member 5C
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LINC00115 long intergenic non-protein coding RNA 115
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCM3AP minichromosome maintenance complex component 3 associated protein
METTL3 methyltransferase like 3
MON2 MON2 homolog (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
MYLK myosin light chain kinase
MYO1D myosin ID
MYOZ3 myozenin 3
MZF1 myeloid zinc finger 1
NGDN neuroguidin, EIF4E binding protein
NTSR1 neurotensin receptor 1 (high affinity)
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PARP3 poly (ADP-ribose) polymerase family, member 3
PGAP1 post-GPI attachment to proteins 1
PGAP3 post-GPI attachment to proteins 3
PHF20L1 PHD finger protein 20-like 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PILRB paired immunoglobin-like type 2 receptor beta
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PVT1 Pvt1 oncogene (non-protein coding)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RALGDS ral guanine nucleotide dissociation stimulator
RARG retinoic acid receptor, gamma
RBM19 RNA binding motif protein 19
RFX7 regulatory factor X, 7
RPL14 ribosomal protein L14
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RTN2 reticulon 2
SAMD4A sterile alpha motif domain containing 4A
SCAPER S-phase cyclin A-associated protein in the ER
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGSM3 small G protein signaling modulator 3
SIN3B SIN3 transcription regulator family member B
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SOCS6 suppressor of cytokine signaling 6
SPATA2L spermatogenesis associated 2-like
SPATA5L1 spermatogenesis associated 5-like 1
SPN sialophorin
SPTAN1 spectrin, alpha, non-erythrocytic 1
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYK spleen tyrosine kinase
TLR2 toll-like receptor 2
TRA2A transformer 2 alpha homolog (Drosophila)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VEGFA vascular endothelial growth factor A
WDR61 WD repeat domain 61
ZC3H7B zinc finger CCCH-type containing 7B
ZNF174 zinc finger protein 174
ZNF267 zinc finger protein 267
ZNF492 zinc finger protein 492
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD11 abhydrolase domain containing 11
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGO4 argonaute RISC catalytic component 4
ALG3 ALG3, alpha-1,3- mannosyltransferase
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
ANG angiogenin, ribonuclease, RNase A family, 5
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
C11ORF63 chromosome 11 open reading frame 63
C16ORF45 chromosome 16 open reading frame 45
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1R complement component 1, r subcomponent
C21ORF91 chromosome 21 open reading frame 91
C4BPA complement component 4 binding protein, alpha
C9ORF114 chromosome 9 open reading frame 114
CCNT1 cyclin T1
CIDEB cell death-inducing DFFA-like effector b
CIDEC cell death-inducing DFFA-like effector c
CTGF connective tissue growth factor
CUZD1 CUB and zona pellucida-like domains 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DOLPP1 dolichyldiphosphatase 1
DUSP2 dual specificity phosphatase 2
EAF2 ELL associated factor 2
ECM1 extracellular matrix protein 1
ELOVL4 ELOVL fatty acid elongase 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPN3 epsin 3
ETAA1 Ewing tumor-associated antigen 1
ETNK2 ethanolamine kinase 2
EXD3 exonuclease 3'-5' domain containing 3
EXOSC5 exosome component 5
FBRS fibrosin
FBXL2 F-box and leucine-rich repeat protein 2
FOXC1 forkhead box C1
FUZ fuzzy planar cell polarity protein
GPATCH2L G patch domain containing 2-like
HDAC7 histone deacetylase 7
HIST1H3G histone cluster 1, H3g
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFT122 intraflagellar transport 122
IL6 interleukin 6
INF2 inverted formin, FH2 and WH2 domain containing
KIAA0930 KIAA0930
LMO7 LIM domain 7
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGEH1 melanoma antigen family H1
MAP2 microtubule-associated protein 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MORN1 MORN repeat containing 1
MTERF4 mitochondrial transcription termination factor 4
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MXD3 MAX dimerization protein 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
NSUN6 NOP2/Sun domain family, member 6
NXPE3 neurexophilin and PC-esterase domain family, member 3
NYNRIN NYN domain and retroviral integrase containing
OLFML2A olfactomedin-like 2A
ORAI3 ORAI calcium release-activated calcium modulator 3
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PAQR4 progestin and adipoQ receptor family member IV
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLH polymerase (DNA directed), eta
POLM polymerase (DNA directed), mu
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PSKH1 protein serine kinase H1
PTCD2 pentatricopeptide repeat domain 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RECQL4 RecQ protein-like 4
RHOBTB2 Rho-related BTB domain containing 2
S100A3 S100 calcium binding protein A3
SCEL sciellin
SCIN scinderin
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD1A SET domain containing 1A
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD5 StAR-related lipid transfer (START) domain containing 5
TEX40 testis expressed 40
TRIM25 tripartite motif containing 25
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3C tubulin, alpha 3c
TUBB2B tubulin, beta 2B class IIb
XAB2 XPA binding protein 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY2 YY2 transcription factor
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF232 zinc finger protein 232
ZNF408 zinc finger protein 408
ZNF41 zinc finger protein 41
ZNF415 zinc finger protein 415
ZNF571 zinc finger protein 571
ZNF573 zinc finger protein 573
ZNF675 zinc finger protein 675