(+/-)-catechin-3012 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the (+/-)-catechin-3012 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ACOX2 acyl-CoA oxidase 2, branched chain
ACTA2 actin, alpha 2, smooth muscle, aorta
ADCK2 aarF domain containing kinase 2
AKAP6 A kinase (PRKA) anchor protein 6
APLP2 amyloid beta (A4) precursor-like protein 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATP9A ATPase, class II, type 9A
AXIN1 axin 1
BCL2L1 BCL2-like 1
BIRC7 baculoviral IAP repeat containing 7
BMP7 bone morphogenetic protein 7
CALD1 caldesmon 1
CD58 CD58 molecule
CD7 CD7 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CHMP6 charged multivesicular body protein 6
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL5A1 collagen, type V, alpha 1
COMMD4 COMM domain containing 4
CPN2 carboxypeptidase N, polypeptide 2
CRAT carnitine O-acetyltransferase
CREB3L1 cAMP responsive element binding protein 3-like 1
CRYBB1 crystallin, beta B1
DCC DCC netrin 1 receptor
DLG4 discs, large homolog 4 (Drosophila)
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAM127B family with sequence similarity 127, member B
FBP1 fructose-1,6-bisphosphatase 1
FCMR Fc fragment of IgM receptor
FDPS farnesyl diphosphate synthase
GAS6 growth arrest-specific 6
GJA8 gap junction protein, alpha 8, 50kDa
GLI2 GLI family zinc finger 2
GRM4 glutamate receptor, metabotropic 4
GSPT1 G1 to S phase transition 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IBSP integrin-binding sialoprotein
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL4 interleukin 4
INPP5K inositol polyphosphate-5-phosphatase K
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KHK ketohexokinase (fructokinase)
KIF1A kinesin family member 1A
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LOC1720 dihydrofolate reductase pseudogene
LZTS1 leucine zipper, putative tumor suppressor 1
MAP2 microtubule-associated protein 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MINK1 misshapen-like kinase 1
MRPS12 mitochondrial ribosomal protein S12
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MX1 MX dynamin-like GTPase 1
MYLK myosin light chain kinase
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NIPAL3 NIPA-like domain containing 3
NPPA natriuretic peptide A
NPPC natriuretic peptide C
NPR1 natriuretic peptide receptor 1
NPVF neuropeptide VF precursor
ONECUT2 one cut homeobox 2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAX2 paired box 2
PDE4B phosphodiesterase 4B, cAMP-specific
PDX1 pancreatic and duodenal homeobox 1
POU5F1P4 POU class 5 homeobox 1 pseudogene 4
PVR poliovirus receptor
RAB11B RAB11B, member RAS oncogene family
SGPL1 sphingosine-1-phosphate lyase 1
SLC12A8 solute carrier family 12, member 8
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SPARCL1 SPARC-like 1 (hevin)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SSBP2 single-stranded DNA binding protein 2
SSH3 slingshot protein phosphatase 3
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SYN3 synapsin III
TAPT1 transmembrane anterior posterior transformation 1
TDRD12 tudor domain containing 12
TLX3 T-cell leukemia homeobox 3
TPM2 tropomyosin 2 (beta)
TRIM45 tripartite motif containing 45
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TRPS1 trichorhinophalangeal syndrome I
TSC2 tuberous sclerosis 2
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
WWTR1 WW domain containing transcription regulator 1
XCL1 chemokine (C motif) ligand 1
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BHMT2 betaine--homocysteine S-methyltransferase 2
C11ORF63 chromosome 11 open reading frame 63
C11ORF68 chromosome 11 open reading frame 68
C3ORF14 chromosome 3 open reading frame 14
C6ORF10 chromosome 6 open reading frame 10
C6ORF47 chromosome 6 open reading frame 47
CAPN5 calpain 5
CASS4 Cas scaffolding protein family member 4
CCDC71 coiled-coil domain containing 71
CCDC88C coiled-coil domain containing 88C
CLEC10A C-type lectin domain family 10, member A
CNTLN centlein, centrosomal protein
COL19A1 collagen, type XIX, alpha 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CST1 cystatin SN
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DAGLA diacylglycerol lipase, alpha
ENO3 enolase 3 (beta, muscle)
EPX eosinophil peroxidase
FAM46C family with sequence similarity 46, member C
FBXO40 F-box protein 40
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GBP2 guanylate binding protein 2, interferon-inducible
GEM GTP binding protein overexpressed in skeletal muscle
GUCA2A guanylate cyclase activator 2A (guanylin)
HAMP hepcidin antimicrobial peptide
HDAC7 histone deacetylase 7
HIST1H3I histone cluster 1, H3i
HOXA2 homeobox A2
HOXA6 homeobox A6
HOXC8 homeobox C8
HOXD10 homeobox D10
IFNA14 interferon, alpha 14
IFT140 intraflagellar transport 140
IFT81 intraflagellar transport 81
JAM3 junctional adhesion molecule 3
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLK11 kallikrein-related peptidase 11
LHX2 LIM homeobox 2
LTA lymphotoxin alpha
LZTR1 leucine-zipper-like transcription regulator 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYBPC1 myosin binding protein C, slow type
MYH4 myosin, heavy chain 4, skeletal muscle
MYO15A myosin XVA
OSBP2 oxysterol binding protein 2
OVGP1 oviductal glycoprotein 1, 120kDa
PADI2 peptidyl arginine deiminase, type II
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PBOV1 prostate and breast cancer overexpressed 1
PCDHGB6 protocadherin gamma subfamily B, 6
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PECR peroxisomal trans-2-enoyl-CoA reductase
PFN2 profilin 2
PHKG1 phosphorylase kinase, gamma 1 (muscle)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHS1 pleckstrin homology domain containing, family S member 1
POM121 POM121 transmembrane nucleoporin
PRO2964 uncharacterized protein PRO2964
PYGB phosphorylase, glycogen; brain
QSER1 glutamine and serine rich 1
RAB17 RAB17, member RAS oncogene family
RANBP17 RAN binding protein 17
RAP1GAP2 RAP1 GTPase activating protein 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM12B-AS1 RBM12B antisense RNA 1
RNF31 ring finger protein 31
RPL23AP32 ribosomal protein L23a pseudogene 32
SCN5A sodium channel, voltage gated, type V alpha subunit
SCRT1 scratch family zinc finger 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC35F6 solute carrier family 35, member F6
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMR3A submaxillary gland androgen regulated protein 3A
SPTBN5 spectrin, beta, non-erythrocytic 5
SYCP2 synaptonemal complex protein 2
TAGLN transgelin
TFDP3 transcription factor Dp family, member 3
THRAP3 thyroid hormone receptor associated protein 3
TRAF1 TNF receptor-associated factor 1
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
UNC13A unc-13 homolog A (C. elegans)
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
VEGFB vascular endothelial growth factor B
YPEL1 yippee-like 1 (Drosophila)
ZNF415 zinc finger protein 415
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747