RNR1 Gene

Name RNA, ribosomal cluster 1
Description The genes encoding the rRNA components of the ribosome are organized as tandem rDNA repeating units, designated RNR1 through RNR5, in the p12 region of chromosomes 13, 14, 15, 21 and 22. Each rDNA unit encodes a 45S rRNA which serves as the precursor for an 18S, 5.8S and 28S rRNA. The number of rDNA repeating units varies between individuals and from chromosome to chromosome, although usually 30 to 40 repeats are found on each chromosome. This ribosomal repeating unit located on chromosome 13 is not currently annotated on the reference genome. [provided by RefSeq, Mar 2009]
NCBI Gene ID 6052
API
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Predicted Functions View RNR1's ARCHS4 Predicted Functions.
Co-expressed Genes View RNR1's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View RNR1's ARCHS4 Predicted Functions.

Functional Associations

RNR1 has 369 functional associations with biological entities spanning 5 categories (chemical, disease, phenotype or trait, functional term, phrase or reference, cell line, cell type or tissue, gene, protein or microRNA) extracted from 8 datasets.

Click the + buttons to view associations for RNR1 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CTD Gene-Chemical Interactions chemicals interacting with RNR1 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
CTD Gene-Disease Associations diseases associated with RNR1 gene/protein from the curated CTD Gene-Disease Associations dataset.
GAD Gene-Disease Associations diseases associated with RNR1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
GeneRIF Biological Term Annotations biological terms co-occuring with RNR1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
HPO Gene-Disease Associations phenotypes associated with RNR1 gene by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.
Hub Proteins Protein-Protein Interactions interacting hub proteins for RNR1 from the curated Hub Proteins Protein-Protein Interactions dataset.
HuGE Navigator Gene-Phenotype Associations phenotypes associated with RNR1 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles cell lines with high or low expression of RNR1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.