MIR664B Gene

Name microRNA 664b
Description microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Synonyms MIR-664B, HSA-MIR-664B, MIR644B
NCBI Gene ID 100847052
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Predicted Functions View MIR664B's ARCHS4 Predicted Functions.
Co-expressed Genes View MIR664B's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View MIR664B's ARCHS4 Predicted Functions.

Functional Associations

MIR664B has 133 functional associations with biological entities spanning 1 categories (cell line, cell type or tissue) extracted from 2 datasets.

Click the + buttons to view associations for MIR664B from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of MIR664B gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of MIR664B gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.