|Name||opsin locus control region|
|Description||The genes encoding the red (OPN1LW; MIM 300822) and green (OPN1MW; MIM 300821) photopigments are arranged in a head-to-tail tandem array on chromosome Xq28, with a single red pigment gene followed by 1 or more green pigment genes. A master switch for the genes of this locus, called the locus control region (LCR), is located between 3.1 kb and 3.7 kb 5-prime of the gene array and has been shown to be essential for expression of both the red and green pigment genes as well as cone-specific expression of the genes and their segregated expression in separate cones (summary by Deeb, 2005 [PubMed 15811001]).[supplied by OMIM, Mar 2011]|
|NCBI Gene ID||100534624|
|Expression in Tissues and Cell Lines||
LCR-OPSIN has 1 functional associations with biological entities spanning 1 categories (disease, phenotype or trait) extracted from 1 datasets.
Click the + buttons to view associations for LCR-OPSIN from the datasets below.
If available, associations are ranked by standardized value
|CTD Gene-Disease Associations||diseases associated with LCR-OPSIN gene/protein from the curated CTD Gene-Disease Associations dataset.|