AK6 Gene

HGNC Family Adenylate kinases (AK)
Name adenylate kinase 6
Description This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5' exons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Synonyms HCINAP, CGI-137, AD-004, CIP
Proteins KAD6_HUMAN
NCBI Gene ID 102157402
API
Download Associations
Predicted Functions View AK6's ARCHS4 Predicted Functions.
Co-expressed Genes View AK6's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View AK6's ARCHS4 Predicted Functions.

Functional Associations

AK6 has 563 functional associations with biological entities spanning 5 categories (functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 14 datasets.

Click the + buttons to view associations for AK6 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing AK6 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores cellular components co-occuring with AK6 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
DISEASES Text-mining Gene-Disease Assocation Evidence Scores diseases co-occuring with AK6 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
GeneRIF Biological Term Annotations biological terms co-occuring with AK6 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of AK6 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of AK6 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GO Biological Process Annotations biological processes involving AK6 gene from the curated GO Biological Process Annotations dataset.
GO Cellular Component Annotations cellular components containing AK6 protein from the curated GO Cellular Component Annotations dataset.
GO Molecular Function Annotations molecular functions performed by AK6 gene from the curated GO Molecular Function Annotations dataset.
HPA Tissue Protein Expression Profiles tissues with high or low expression of AK6 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
Hub Proteins Protein-Protein Interactions interacting hub proteins for AK6 from the curated Hub Proteins Protein-Protein Interactions dataset.
InterPro Predicted Protein Domain Annotations protein domains predicted for AK6 protein from the InterPro Predicted Protein Domain Annotations dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores tissues with high expression of AK6 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores tissues co-occuring with AK6 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.