SYNGAP1 Q96PV0 NA GEF Cytosol RAP1A P62834 P62835 GTPase Cytosol _ GAP 15312654
GSK3A P49840 NA Kinase Cytosol JUN P05412 P05627 TF Nucleus _ Phosphorylation 16023596
GSK3A P49840 NA Kinase Cytosol JUN P05412 P05627 TF Nucleus _ Phosphorylation 1846781
RIPK1 Q13546 Q60855 Kinase Cytosol SQSTM1 Q13501 Q64337 Adapter Cytosol + Binding 10356400
CAMK2A Q9UQM7 P11798 Kinase Cytosol MAP2 P11137 P20357 Cytoskeleton Cytosol + Phosphorylation 7890745
CAMK2A Q9UQM7 P11798 Kinase Cytosol MAP2 P11137 P20357 Cytoskeleton Cytosol + Phosphorylation 9341200
CAMK2A Q9UQM7 P11798 Kinase Cytosol MAP2 P11137 P20357 Cytoskeleton Cytosol + Phosphorylation 2561875
ARRB1 P49407 Q8BWG8 Adapter Cytosol ADRB2 P07550 P18762 Receptor Membrane _ Binding 11171997
ATF2 P15336 P16951 TF Nucleus TRE NA NA DNA Nucleus + Binding 2320002
MAPK1 P28482 P63085 Kinase Cytosol FOS P01100 P01101 TF Nucleus + Phosphorylation 16123044
PRMT1 Q99873 Q9JIF0 Methylase Cytosol SF1 Q15637 Q64213 Adapter Cytosol + Methylation 12529443
PRKCA P17252 P20444 Kinase Cytosol PICK1 Q9NRD5 Q62083 Adapter Cytosol 0 Phosphorylation 10340301
PRKCA P17252 P20444 Kinase Cytosol PICK1 Q9NRD5 Q62083 Adapter Cytosol 0 Phosphorylation 11007882
PRKCA P17252 P20444 Kinase Cytosol PICK1 Q9NRD5 Q62083 Adapter Cytosol 0 Phosphorylation 9405395
PRKCA P17252 P20444 Kinase Cytosol PICK1 Q9NRD5 Q62083 Adapter Cytosol 0 Phosphorylation 7844141
SRC P12931 P05480 Kinase Cytosol SF1 Q15637 Q64213 Adapter Cytosol + Phosphorylation 7512694
SRC P12931 P05480 Kinase Cytosol SF1 Q15637 Q64213 Adapter Cytosol + Phosphorylation 2236073
SRC P12931 P05480 Kinase Cytosol SF1 Q15637 Q64213 Adapter Cytosol + Phosphorylation 14643926
SRC P12931 P05480 Kinase Cytosol SF1 Q15637 Q64213 Adapter Cytosol + Phosphorylation 7537265
SRC P12931 P05480 Kinase Cytosol SF1 Q15637 Q64213 Adapter Cytosol + Phosphorylation 7512695
MDM2 Q00987 P23804 Ubiquitinase Nucleus TP53BP1 Q12888 P70399 TF Nucleus _ Ubiquitination 14671306
PPP2R5C Q13362 Q60996 Phosphatase Cytosol AKT1 P31749 P31750 Kinase Cytosol _ Dephosphorylation 11897496
GRIN2A Q12879 P35436 Receptor Membrane SPTBN2 O15020 NA Cytoskeleton Cytosol 0 Binding 11677266
GRIN2A Q12879 P35436 Receptor Membrane SPTBN2 O15020 NA Cytoskeleton Cytosol 0 Binding 9670010
FRAP1 P42345 Q9JLN9 Kinase Cytosol PPP2R5C Q13362 Q60996 Phosphatase Cytosol _ Phosphorylaion 10200280
BAD Q92934 Q61337 Bcl2Family Mitochondria BCL2 P10415 P10417 Bcl2Family Mitochondria + Binding 7834748
BAD Q92934 Q61337 Bcl2Family Mitochondria BCL2 P10415 P10417 Bcl2Family Mitochondria + Binding 9388232
MAP2K1IP1 Q9UHA4 O88653 Adapter Cytosol MAP4K1 Q92918 P70218 Kinase Cytosol + Binding 9733512
RASGRF1 Q13972 P27671 GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 7828890
RASGRF1 Q13972 P27671 GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 9430727
RASGRF1 Q13972 P27671 GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 11560935
RASGRF1 Q13972 P27671 GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 9379834
RASGRF1 Q13972 P27671 GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 9032266
RASGRF1 Q13972 P27671 GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 1379346
RDX P35241 P26043 Adapter Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol 0 Binding 10816569
ITPR1 Q14643 P11881 Channel ER HOMER2 Q9NSB8 Q9QWW1 Adapter Cytosol 0 Binding 9808459
RALBP1 Q15311 Q62172 GAP Cytosol RAC1 P63000 P63001 GTPase Cytosol _ GAP 9395447
SRC P12931 P05480 Kinase Cytosol MUSK O15146 Q61006 Kinase Cytosol + Phosphorylation 11356869
KCNJ2 P63252 P35561 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 8893032
OPRK1 P41145 P33534 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 15082510
GRB2 P62993 Q60631 Adapter Cytosol SOS1 Q07889 Q62245 GEF Cytosol + Binding 8493579
GRB2 P62993 Q60631 Adapter Cytosol SOS1 Q07889 Q62245 GEF Cytosol + Binding 8479540
GRIA1 P42261 P23818 Channel Membrane AP2S1 P53680 P62743 Adapter Vesicles 0 Binding 12441055
SRC P12931 P05480 Kinase Cytosol GABRA1 P14867 P62812 Receptor Membrane + Phosphorylation 7566089
PDE1B Q01064 Q01065 PDE Cytosol cGMP NA NA Messenger Cytosol _ PDE 7678006
PDE1B Q01064 Q01065 PDE Cytosol cGMP NA NA Messenger Cytosol _ PDE 1326531
PDE1B Q01064 Q01065 PDE Cytosol cGMP NA NA Messenger Cytosol _ PDE 8537356
GRIK1 P39086 Q60934 Channel Membrane DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 12597860
STX3 Q13277 Q64704 Vesicle Vesicles STXBP1 P61764 O08599 Vesicle Vesicles 0 Binding 15175344
STX3 Q13277 Q64704 Vesicle Vesicles STXBP1 P61764 O08599 Vesicle Vesicles 0 Binding 8108429
STX3 Q13277 Q64704 Vesicle Vesicles STXBP1 P61764 O08599 Vesicle Vesicles 0 Binding 9478941
STX3 Q13277 Q64704 Vesicle Vesicles STXBP1 P61764 O08599 Vesicle Vesicles 0 Binding 9933594
CTTN Q14247 Q60598 Cytoskeleton Cytosol SHANK1 Q9Y566 NA Adapter Cytosol 0 Binding 10433268
SH3KBP1 Q96B97 Q8R550 Phosphatase Cytosol JAK2 O60674 Q62120 Kinase Cytosol + Dephosphorylation 8943354
PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol DAG NA NA Lipid Cytosol + Cleavage 6325926
PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol DAG NA NA Lipid Cytosol + Cleavage 7076678
PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol DAG NA NA Lipid Cytosol + Cleavage 7142213
CASP3 P42574 P70677 Protease Cytosol DFFA O00273 O54786 Inhibitor Cytosol _ Cleavage 9422513
CASP3 P42574 P70677 Protease Cytosol DFFA O00273 O54786 Inhibitor Cytosol _ Cleavage 12655299
RBP1 P09455 Q00915 Receptor Membrane IRS1 P35568 P35569 Adapter Cytosol 0 Binding 11313948
JUN P05412 P05627 TF Nucleus GDNF P39905 P48540 TF Nucleus + Binding 8290251
PIP2 NA NA Lipid Cytosol DOCK2 Q92608 Q8C3J5 Vesicle Vesicles + Binding 11027523
GSK3A P49840 NA Kinase Cytosol ANAPC1 Q9H1A4 P53995 Adapter Cytosol + Phosphorylation 9601641
GSK3A P49840 NA Kinase Cytosol ANAPC1 Q9H1A4 P53995 Adapter Cytosol + Phosphorylation 8638126
SH3KBP1 Q96B97 Q8R550 Phosphatase Cytosol SPRY1 O43609 Q9QXV9 Adapter Cytosol _ Dephosphorylation 15031289
CALM3 P62158 P62204 Activator Cytosol RASGRF1 Q13972 P27671 GEF Cytosol + Binding 7637786
CALM3 P62158 P62204 Activator Cytosol RASGRF1 Q13972 P27671 GEF Cytosol + Binding 8756648
PPP1R9B Q96SB3 Q6R891 Cytoskeleton Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol + Binding 9275233
PPP1R9B Q96SB3 Q6R891 Cytoskeleton Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol + Binding 12417592
PSEN1 P49768 P49769 Protease Membrane SRI P30626 Q6P069 Adapter Cytosol 0 Binding 10748169
PRKACA P17612 P05132 Kinase Cytosol CACNA1C Q13936 Q01815 Channel Membrane _ Phosphorylation 10984483
PRKACA P17612 P05132 Kinase Cytosol CACNA1C Q13936 Q01815 Channel Membrane _ Phosphorylation 2174428
PRKACA P17612 P05132 Kinase Cytosol CACNA1C Q13936 Q01815 Channel Membrane _ Phosphorylation 10514522
PRKACA P17612 P05132 Kinase Cytosol CACNA1C Q13936 Q01815 Channel Membrane _ Phosphorylation 7621818
PRKACA P17612 P05132 Kinase Cytosol CACNA1A O00555 P97445 Channel Membrane _ Phosphorylation 12410316
CALM3 P62158 P62204 Activator Cytosol SPTBN2 O15020 NA Cytoskeleton Cytosol _ Binding 2492524
FOS P01100 P01101 TF Nucleus GDNF P39905 P48540 TF Nucleus + Binding 8290251
WNT6 Q9Y6F9 P22727 Ligand Extracellular LRP16 Q9BQ69 Q922B1 Receptor Membrane + Binding 12857724
RAC1 P63000 P63001 GTPase Cytosol MAP3K10 Q02779 NA Kinase Cytosol + Binding 10799501
PIP3 NA NA Lipid Membrane PSCD2 Q99418 P63034 GEF Cytosol + Binding 10449335
EFNB2 P52799 P52800 Receptor Membrane HAPIP O60229 NA GEF Cytosol + Phosphorylation 12546821
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol PIK3CA P42336 P42337 Kinase Cytosol _ Ubiquitination 11087752
SYK P43405 P48025 Kinase Cytosol PLCG1 P19174 Q62077 Phospholipase Cytosol + Phosphorylation 7744830
SYK P43405 P48025 Kinase Cytosol PLCG1 P19174 Q62077 Phospholipase Cytosol + Phosphorylation 8657103
MAPK1 P28482 P63085 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Phosphorylation 8622996
MAPK1 P28482 P63085 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Phosphorylation 8702879
STON2 Q8WXE9 Q8BZ60 Adapter Vesicles EPS15 P42566 P42567 Adapter Cytosol 0 Binding 11381094
PAK1 Q13153 O88643 Kinase Cytosol ABL1 P00519 P00520 Kinase Cytosol + Phosphorylation 11121037
SUMO3 P55854 Q9Z172 Sumo Cytosol JUN P05412 P05627 TF Nucleus _ Sumolation 16055710
CALM3 P62158 P62204 Activator Cytosol ADD1 P35611 Q9QYC0 Adapter Cytosol + Binding 9679146
CALM3 P62158 P62204 Activator Cytosol ADD1 P35611 Q9QYC0 Adapter Cytosol + Binding 8810272
LYN P07948 P25911 Kinase Cytosol SYK P43405 P48025 Kinase Cytosol 0 Binding 7831290
ARHGAP1 Q07960 NA GTPase Cytosol PRKCA P17252 P20444 Kinase Cytosol 0 Binding 11284700
ACH NA NA Ligand Extracellular CHRNA7 P36544 P49582 Receptor Membrane + Binding 977572
ACH NA NA Ligand Extracellular CHRNA7 P36544 P49582 Receptor Membrane + Binding 3753746
EIF3S1 O75822 Q66JS6 Ribosome Ribosomes EIF4G2 P78344 Q62448 Ribosome Ribosomes + Binding 11022043
CPLX1 O14810 P63040 Vesicle Vesicles STX3 Q13277 Q64704 Vesicle Vesicles 0 Binding 7553862
SRPR P08240 Q9DBG7 Receptor ER SEC61A1 P61619 P61620 Channel ER + Binding 12913112
CALM3 P62158 P62204 Activator Cytosol ADRBK1 P25098 Q99MK8 Kinase Cytosol _ Binding 11042191
GNB2 P62879 P62880 Gprotein Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 8156600
MAPK14 Q16539 P47811 Kinase Cytosol JUN P05412 P05627 TF Nucleus + Phosphorylation 12475989
RAP2A P10114 Q80ZJ1 GTPase Cytosol NRAS P01111 P08556 GTPase Cytosol + Binding 10085114
PIP2 NA NA Lipid Cytosol ADRBK1 P25098 Q99MK8 Kinase Cytosol _ Binding 7673171
PRKCA P17252 P20444 Kinase Cytosol IRS1 P35568 P35569 Adapter Cytosol _ Phosphorylation 15069075
PTPN11 Q06124 P35235 Phosphatase Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 7522233
PA NA NA Messenger Cytosol SH3KBP1 Q96B97 Q8R550 Phosphatase Cytosol + Binding 10508402
GRIN2A Q12879 P35436 Receptor Membrane PTP1D NA NA Phosphatase Cytosol 0 Binding 10381539
SOS1 Q07889 Q62245 GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 8493579
SOS1 Q07889 Q62245 GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 9690470
SOS1 Q07889 Q62245 GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 7923364
PPP2R5C Q13362 Q60996 Phosphatase Cytosol GSK3A P49840 NA Kinase Cytosol + Dephosphorylation 8524413
PPP2R5C Q13362 Q60996 Phosphatase Cytosol GSK3A P49840 NA Kinase Cytosol + Dephosphorylation 11897496
NTRK1 P04629 NA Receptor Membrane SHC1 P29353 P98083 Adapter Cytosol + Binding 8552402
NTRK1 P04629 NA Receptor Membrane SHC1 P29353 P98083 Adapter Cytosol + Binding 8226808
NTRK1 P04629 NA Receptor Membrane SHC1 P29353 P98083 Adapter Cytosol + Binding 15056278
NTRK1 P04629 NA Receptor Membrane SHC1 P29353 P98083 Adapter Cytosol + Binding 9715270
RAP1A P62834 P62835 GTPase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol _ Binding 12873387
RAP1A P62834 P62835 GTPase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol _ Binding 12446733
RAP1A P62834 P62835 GTPase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol _ Binding 9867809
GRB2 P62993 Q60631 Adapter Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 11877424
GRB2 P62993 Q60631 Adapter Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 9452513
GRB2 P62993 Q60631 Adapter Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 8402898
GRB2 P62993 Q60631 Adapter Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 7505438
PDE4B Q07343 NA PDE Cytosol CAMP P49913 P51437 Messenger Cytosol _ PDE 2542941
PDE4B Q07343 NA PDE Cytosol CAMP P49913 P51437 Messenger Cytosol _ PDE 7998974
IKBKB O14920 O88351 Kinase Cytosol NFKBIA P25963 Q9Z1E3 Inhibitor Cytosol _ Phosphorylation 9252186
PPP2R5C Q13362 Q60996 Phosphatase Cytosol CACNA1C Q13936 Q01815 Channel Membrane + Dephosphorylation 10984483
AKT1 P31749 P31750 Kinase Cytosol TSC1 Q92574 NA GAP Cytosol _ Phosphorylaion 15809346
CASP3 P42574 P70677 Protease Cytosol EIF4G2 P78344 Q62448 Ribosome Ribosomes _ Cleavage 10371215
PRKACA P17612 P05132 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Phosphorylation 3118371
PRKACA P17612 P05132 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Phosphorylation 14557263
PRKACA P17612 P05132 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Phosphorylation 7849051
SRC P12931 P05480 Kinase Cytosol CTTN Q14247 Q60598 Cytoskeleton Cytosol _ Phosphorylation 7680654
GABBR1 Q9UBS5 Q9WV18 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 12917685
PRKCE Q02156 P16054 Kinase Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol 0 Binding 9756923
BAD Q92934 Q61337 Bcl2Family Mitochondria BCL2L1 Q07817 Q64373 Bcl2Family Mitochondria + Binding 9305851
BAD Q92934 Q61337 Bcl2Family Mitochondria BCL2L1 Q07817 Q64373 Bcl2Family Mitochondria + Binding 9388232
BAD Q92934 Q61337 Bcl2Family Mitochondria BCL2L1 Q07817 Q64373 Bcl2Family Mitochondria + Binding 8929531
KCNIP3 Q9Y2W7 P0C092 Adapter Cytosol KCND2 Q9NZV8 Q9Z0V2 Channel Membrane 0 Binding 15356203
KCNIP3 Q9Y2W7 P0C092 Adapter Cytosol KCND2 Q9NZV8 Q9Z0V2 Channel Membrane 0 Binding 12829703
KCNIP3 Q9Y2W7 P0C092 Adapter Cytosol KCND2 Q9NZV8 Q9Z0V2 Channel Membrane 0 Binding 12451113
KCNIP3 Q9Y2W7 P0C092 TF Nucleus KCND1 Q9NSA2 Q03719 Channel Membrane _ Binding 12829703
PLCG1 P19174 Q62077 Phospholipase Cytosol DAG NA NA Lipid Cytosol + Synthesis 2831461
CALM3 P62158 P62204 Activator Cytosol ITPR1 Q14643 P11881 Channel ER _ Binding 10456332
CALM3 P62158 P62204 Activator Cytosol ITPR1 Q14643 P11881 Channel ER _ Binding 7755592
PRKACA P17612 P05132 Kinase Cytosol ADD1 P35611 Q9QYC0 Adapter Cytosol _ Phosphorylation 8810272
RPS6KB1 P23443 Q8BSK8 Kinase Cytosol EEF2K O00418 O08796 GTPase Ribosomes _ Phosphorylation 11500364
SRI P30626 Q6P069 Adapter Cytosol RYR1 P21817 NA Channel ER _ Binding 9312152
SRI P30626 Q6P069 Adapter Cytosol RYR1 P21817 NA Channel ER _ Binding 7592856
BDKRB1 P46663 Q61125 Receptor Membrane GNA11 P29992 P21278 Gprotein Cytosol + Binding 11379050
BCAP31 P51572 Q61335 Adapter ER CASP8 Q14790 O89110 Protease Cytosol _ Binding 9334338
BIRC6 Q9NR09 NA Ubiquitinase Cytosol DIABLO Q9NR28 Q9JIQ3 Inhibitor Mitochondria _ Ubiquitination 15300255
PRKACA P17612 P05132 Kinase Cytosol PTPN5 P54829 P54830 Phosphatase Cytosol _ Phosphorylation 10908600
RIN1 Q13671 Q921Q7 Activator Cytosol NRAS P01111 P08556 GTPase Cytosol _ Binding 12574403
RIN1 Q13671 Q921Q7 Activator Cytosol NRAS P01111 P08556 GTPase Cytosol _ Binding 11784866
DNAJA1 P31689 P63037 Chaperone ER NASCENTCHAIN NA NA Peptide Ribosomes 0 Binding 2005967
DNAJA1 P31689 P63037 Chaperone ER NASCENTCHAIN NA NA Peptide Ribosomes 0 Binding 9585179
CDK5 Q00535 P49615 Kinase Cytosol STX3 Q13277 Q64704 Vesicle Vesicles 0 Binding 9478941
PAK1 Q13153 O88643 Kinase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Phosphorylation 9823899
CALM3 P62158 P62204 Activator Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol + Binding 1722402
CALM3 P62158 P62204 Activator Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol + Binding 7493936
CALM3 P62158 P62204 Activator Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol + Binding 7685187
CAMK2A Q9UQM7 P11798 Kinase Cytosol KCND2 Q9NZV8 Q9Z0V2 Channel Membrane + Phosphorylation 15071113
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol SHC1 P29353 P98083 Adapter Cytosol _ Ubiquitination 11375397
GNAS P63092 P63094 Gprotein Cytosol ADCY5 O95622 P84309 Cyclase Membrane + Binding 9748257
PTPN11 Q06124 P35235 Phosphatase Cytosol GAB1 Q13480 Q9QYY0 Adapter Cytosol _ Dephosphorylation 14701753
GNB2 P62879 P62880 Gprotein Cytosol ADCY2 Q08462 Q80TL1 Cyclase Cytosol + Binding 1962211
GNB2 P62879 P62880 Gprotein Cytosol ADCY2 Q08462 Q80TL1 Cyclase Cytosol + Binding 1312225
GNAS P63092 P63094 Gprotein Cytosol ADCY2 Q08462 Q80TL1 Cyclase Cytosol + Binding 1719547
GNAS P63092 P63094 Gprotein Cytosol ADCY2 Q08462 Q80TL1 Cyclase Cytosol + Binding 9395396
GNAS P63092 P63094 Gprotein Cytosol ADCY1 Q08828 O88444 Cyclase Cytosol + Binding 210183
GNAS P63092 P63094 Gprotein Cytosol ADCY1 Q08828 O88444 Cyclase Cytosol + Binding 6935665
GNAS P63092 P63094 Gprotein Cytosol ADCY1 Q08828 O88444 Cyclase Cytosol + Binding 2022671
GNB2 P62879 P62880 Gprotein Cytosol ADCY1 Q08828 O88444 Cyclase Cytosol _ Binding 2022671
RPH3A Q9Y2J0 P47708 Vesicle Vesicles RAB3A P20336 P63011 GTPase Vesicles + Binding 8262955
RPH3A Q9Y2J0 P47708 Vesicle Vesicles RAB3A P20336 P63011 GTPase Vesicles + Binding 8266731
RAPGEF2 Q9Y4G8 Q8CHG7 GEF Cytosol RAP2A P10114 Q80ZJ1 GTPase Cytosol + GEF 10608883
ATF2 P15336 P16951 TF Nucleus JUN P05412 P05627 TF Nucleus + Binding 2320002
ADORA1 P30542 Q60612 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 6162091
ADORA1 P30542 Q60612 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 3805010
ADORA1 P30542 Q60612 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 6305455
MAP1A P78559 Q9QYR6 Cytoskeleton Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol 0 Binding 11278895
MAP4K1 Q92918 P70218 Kinase Cytosol MAPK1 P28482 P63085 Kinase Cytosol + Phosphorylation 1381507
MAP4K1 Q92918 P70218 Kinase Cytosol MAPK1 P28482 P63085 Kinase Cytosol + Phosphorylation 8226933
PRKCA P17252 P20444 Kinase Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Phosphorylation 8316301
PRKCA P17252 P20444 Kinase Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Phosphorylation 9115280
MAP3K1 Q13233 P53349 Kinase Cytosol MAPK8 P45983 Q91Y86 Kinase Nucleus + Binding 9405400
RAPGEF2 Q9Y4G8 Q8CHG7 GEF Cytosol RAP1A P62834 P62835 GTPase Cytosol + GEF 10608883
ADRB2 P07550 P18762 Receptor Membrane SLC9A3R1 O14745 P70441 Adapter Cytosol 0 Binding 11882663
GNA11 P29992 P21278 Gprotein Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 12578375
SUMO2 P61956 P61957 Sumo Cytosol FOS P01100 P01101 TF Nucleus _ Sumolation 16055710
PRKCA P17252 P20444 Kinase Cytosol CACNA1C Q13936 Q01815 Channel Membrane _ Phosphorylation 11035786
PRKCA P17252 P20444 Kinase Cytosol CACNA1B Q00975 O55017 Channel Membrane + Phosphorylation 8380626
PRKCA P17252 P20444 Kinase Cytosol CACNA1B Q00975 O55017 Channel Membrane + Phosphorylation 9278528
GNB2 P62879 P62880 Gprotein Cytosol IRS1 P35568 P35569 Adapter Cytosol + Binding 7619809
CREBBP Q92793 P45481 TF Nucleus EIF4G2 P78344 Q62448 Ribosome Ribosomes 0 Binding 15059963
CAMKK2 Q96RR4 Q8C078 Kinase Cytosol CAMK4 Q16566 P08414 Kinase Cytosol + Phosphorylation 8631893
CAMKK2 Q96RR4 Q8C078 Kinase Cytosol CAMK4 Q16566 P08414 Kinase Cytosol + Phosphorylation 7642608
CAMKK2 Q96RR4 Q8C078 Kinase Cytosol CAMK1 Q14012 Q91YS8 Kinase Cytosol + Phosphorylation 10187789
CAMKK2 Q96RR4 Q8C078 Kinase Cytosol CAMK1 Q14012 Q91YS8 Kinase Cytosol + Phosphorylation 8631893
CAMKK2 Q96RR4 Q8C078 Kinase Cytosol CAMK1 Q14012 Q91YS8 Kinase Cytosol + Phosphorylation 7642608
CAMKK2 Q96RR4 Q8C078 Kinase Cytosol CAMK1 Q14012 Q91YS8 Kinase Cytosol + Phosphorylation 10400638
CREBBP Q92793 P45481 TF Nucleus CTNNB1 P35222 Q02248 TF Cytosol + Binding 10769018
EIF1AP1 O75642 NA Ribosome Ribosomes S40 NA NA Ribosome Ribosomes 0 Binding 12860115
NTRK1 P04629 NA Receptor Membrane GRB2 P62993 Q60631 Adapter Cytosol + Binding 10748052
CAMK2A Q9UQM7 P11798 Kinase Cytosol GRIA1 P42261 P23818 Channel Membrane + Phosphorylation 9197267
CAMK2A Q9UQM7 P11798 Kinase Cytosol GRIA1 P42261 P23818 Channel Membrane + Phosphorylation 10077673
CAMK2A Q9UQM7 P11798 Kinase Cytosol GRIA1 P42261 P23818 Channel Membrane + Phosphorylation 7509863
SRC P12931 P05480 Kinase Cytosol RASGRF1 Q13972 P27671 GEF Cytosol + Phosphorylation 10681520
KCND2 Q9NZV8 Q9Z0V2 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 10551270
KCND2 Q9NZV8 Q9Z0V2 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 15269337
BIRC6 Q9NR09 NA Ubiquitinase Cytosol CASP9 P55211 NA Protease Cytosol _ Ubiquitination 15300255
CHRM1 P11229 P12657 Receptor Membrane GNA11 P29992 P21278 Gprotein Cytosol + Binding 12200418
CHRM1 P11229 P12657 Receptor Membrane GNA11 P29992 P21278 Gprotein Cytosol + Binding 14976183
LEF1 Q9UJU2 P27782 TF Nucleus MITF O75030 Q08874 TF Nucleus + Binding 12032083
STXBP1 P61764 O08599 Vesicle Vesicles APBA1 Q02410 NA Vesicle Vesicles 0 Binding 9395480
CHN1 P15882 Q91V57 GAP Cytosol RAC1 P63000 P63001 GTPase Cytosol _ GAP 12446789
PRKACA P17612 P05132 Kinase Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol _ Phosphorylation 7532810
STX3 Q13277 Q64704 Vesicle Vesicles VAMP1 P23763 Q62442 Vesicle Vesicles 0 Binding 8108733
PPP1R12A O14974 Q9DBR7 Phosphatase Cytosol MYO18A Q92614 Q9JMH9 Cytoskeleton Cytosol _ Dephosphorylation 186030
BAK1 Q16611 O08734 Bcl2Family Mitochondria BAD Q92934 Q61337 Bcl2Family Mitochondria _ Binding 9388232
S40 NA NA Ribosome Ribosomes S60 NA NA Ribosome Ribosomes 0 Binding 4909872
S40 NA NA Ribosome Ribosomes S60 NA NA Ribosome Ribosomes 0 Binding 4856634
S40 NA NA Ribosome Ribosomes S60 NA NA Ribosome Ribosomes 0 Binding 14270536
NRAS P01111 P08556 GTPase Cytosol BRAF P15056 P28028 Kinase Cytosol + Binding 7935411
SHC1 P29353 P98083 Adapter Cytosol SOS1 Q07889 Q62245 GEF Cytosol + Binding 8114695
NGFB P01138 P01139 Ligand Extracellular NGFR P08138 Q9Z0W1 Receptor Membrane + Binding 15883381
RCS NA NA Inhibitor Cytosol CALM3 P62158 P62204 Activator Cytosol _ Binding 15499021
CABIN1 Q9Y6J0 NA Inhibitor Cytosol PPP3R1 P63098 Q63810 Phosphatase Cytosol _ Binding 9660798
SRP54 P61011 P14576 Adapter Ribosomes SRPR P08240 Q9DBG7 Receptor ER + Binding 12913112
DLG1 Q12959 Q811D0 Adapter Cytosol EPB41 P11171 P48193 Adapter Cytosol 0 Binding 7937897
RAP2A P10114 Q80ZJ1 GTPase Cytosol RALGDS Q12967 Q03385 GEF Cytosol + Binding 10085114
SF1 Q15637 Q64213 Adapter Cytosol RASGRP3 Q8IV61 NA GAP Cytosol 0 Binding 9571195
SF1 Q15637 Q64213 Adapter Cytosol RASGRP3 Q8IV61 NA GAP Cytosol 0 Binding 9743338
PICK1 Q9NRD5 Q62083 Adapter Cytosol GRIA1 P42261 P23818 Channel Membrane 0 Binding 10340301
ITGB1 P05556 P09055 CellAdhesion Membrane ILK Q13418 O55222 Kinase Cytosol + Binding 8538749
AKAP5 P24588 NA Adapter Cytosol PRKACA P17612 P05132 Kinase Cytosol 0 Binding 9620705
PPP1CC P36873 P63087 Phosphatase Cytosol CREB1 P16220 Q01147 TF Nucleus _ Dephosphorylation 8195196
RAP1A P62834 P62835 GTPase Cytosol RALGDS Q12967 Q03385 GEF Cytosol + Binding 7809086
RAP1A P62834 P62835 GTPase Cytosol RALGDS Q12967 Q03385 GEF Cytosol + Binding 8636102
TUBA3 Q71U36 NA Cytoskeleton Cytosol SYNTABULIN NA NA Adapter Cytosol 0 Binding 15459722
PTK2 Q05397 P34152 Kinase Cytosol SRC P12931 P05480 Kinase Cytosol + Binding 7505391
CAPN1 P07384 O35350 Protease Cytosol MAPT P10636 P10637 Activator Cytosol _ Cleavage 1730702
ADRA1A P35348 P97718 Receptor Membrane GNA11 P29992 P21278 Gprotein Cytosol + Binding 1334487
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol GRB2 P62993 Q60631 Adapter Cytosol _ Ubiquitination 11375397
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol GRB2 P62993 Q60631 Adapter Cytosol _ Ubiquitination 8626404
MAP3K5 Q99683 O35099 Kinase Cytosol MAP2K4 P45985 P47809 Kinase Cytosol + Phosphorylation 8974401
CASP3 P42574 P70677 Protease Cytosol PPP3R1 P63098 Q63810 Phosphatase Cytosol + Cleavage 11478781
CASP3 P42574 P70677 Protease Cytosol PPP3R1 P63098 Q63810 Phosphatase Cytosol + Cleavage 10898953
REPS1 Q96D71 O54916 Adapter Cytosol CRK P46108 Q64010 Adapter Cytosol 0 Binding 9395447
SQSTM1 Q13501 Q64337 Adapter Cytosol PRKCZ Q05513 Q02956 Kinase Cytosol + Binding 11158308
PPM1F P49593 Q8CGA0 Phosphatase Cytosol CAMK4 Q16566 P08414 Kinase Cytosol _ Dephosphorylation 10814834
CAPN1 P07384 O35350 Protease Cytosol MAP2 P11137 P20357 Cytoskeleton Cytosol _ Cleavage 8391085
PPM1F P49593 Q8CGA0 Phosphatase Cytosol CAMK1 Q14012 Q91YS8 Kinase Cytosol _ Dephosphorylation 9442023
PPM1F P49593 Q8CGA0 Phosphatase Cytosol CAMK1 Q14012 Q91YS8 Kinase Cytosol _ Dephosphorylation 10814834
ROCK2 O75116 P70336 Kinase Cytosol PPP1R14A Q96A00 Q91VC7 Inhibitor Cytosol + Phosphorylation 10869555
PRKCA P17252 P20444 Kinase Cytosol NRGN Q92686 P60761 Inhibitor Cytosol _ Phosphorylation 1824695
TUBA3 Q71U36 NA Cytoskeleton Cytosol GRB2 P62993 Q60631 Adapter Cytosol 0 Binding 8910394
RHEB Q15382 Q921J2 Adapter Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Binding 9001246
CALCIUM NA NA Messenger Cytosol SYT1 P21579 P46096 Vesicle Vesicles + Binding 1589771
CALCIUM NA NA Messenger Cytosol SYT1 P21579 P46096 Vesicle Vesicles + Binding 8253763
CALCIUM NA NA Messenger Cytosol SYT1 P21579 P46096 Vesicle Vesicles + Binding 7559535
SSTR1 P30872 P30873 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 8145728
PDGFRB P09619 P05622 Receptor Membrane PLCG1 P19174 Q62077 Phospholipase Cytosol + Phosphorylation 2472219
ROCK2 O75116 P70336 Kinase Cytosol PPP1R12A O14974 Q9DBR7 Phosphatase Cytosol _ Phosphorylation 11287000
STX3 Q13277 Q64704 Vesicle Vesicles SLC1A3 P43003 P56564 Transporter Membrane 0 Binding 9698305
LHX6 Q9UPM6 O88706 Antagonist Cytosol FZD1 Q9UP38 O70421 Receptor Membrane _ Binding 12354775
PLCG1 P19174 Q62077 Phospholipase Cytosol PIP2 NA NA Lipid Cytosol _ Cleavage 2472219
SEROTONIN NA NA Ligand Extracellular HTR2C P28335 P34968 Receptor Membrane + Binding 3473504
SEROTONIN NA NA Ligand Extracellular HTR2C P28335 P34968 Receptor Membrane + Binding 3399891
SEROTONIN NA NA Ligand Extracellular HTR2A P28223 P35363 Receptor Membrane + Binding 6483122
SEROTONIN NA NA Ligand Extracellular HTR2A P28223 P35363 Receptor Membrane + Binding 2300586
SEROTONIN NA NA Ligand Extracellular HTR2A P28223 P35363 Receptor Membrane + Binding 1722404
DUSP10 Q9Y6W6 Q9ESS0 Phosphatase Cytosol MAPK14 Q16539 P47811 Kinase Cytosol _ Dephosphorylation 11790549
PPP3R1 P63098 Q63810 Phosphatase Cytosol PPP1R1B Q9UD71 Q60829 Inhibitor Cytosol _ Dephosphorylation 6330098
PPP3R1 P63098 Q63810 Phosphatase Cytosol PPP1R1B Q9UD71 Q60829 Inhibitor Cytosol _ Dephosphorylation 2153935
PPP3R1 P63098 Q63810 Phosphatase Cytosol PPP1R1A Q13522 Q9ERT9 Inhibitor Cytosol _ Dephosphorylation 7515479
RPS6KA1 Q15418 P18653 Kinase Cytosol EEF2K O00418 O08796 GTPase Ribosomes _ Phosphorylation 11500364
SEROTONIN NA NA Ligand Extracellular HTR1A P08908 Q64264 Receptor Membrane + Binding 3041227
SEROTONIN NA NA Ligand Extracellular HTR1A P08908 Q64264 Receptor Membrane + Binding 3138543
SEROTONIN NA NA Ligand Extracellular HTR1A P08908 Q64264 Receptor Membrane + Binding 2156831
JUND P17535 P15066 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 1827203
JUND P17535 P15066 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 12192032
GNA13 Q14344 P27601 Gprotein Cytosol ARHGEF1 Q92888 Q61210 GEF Cytosol + Binding 9641916
PRKG2 Q13237 Q61410 Kinase Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol + Phosphorylation 7532810
EFNB2 P52799 P52800 Receptor Membrane RASGRP3 Q8IV61 NA GAP Cytosol + Phosphorylation 9233798
GIT1 Q9Y2X7 Q68FF6 Adapter Cytosol ARHGEF7 Q14155 Q9ES28 GEF Cytosol 0 Binding 12695502
GNA12 Q03113 P27600 Gprotein Cytosol ARHGEF1 Q92888 Q61210 GEF Cytosol + Binding 9641916
AP1B1 Q10567 O35643 Adapter Cytosol GABRA1 P14867 P62812 Receptor Membrane _ Binding 11050117
ZAP70 P43403 P43404 Kinase Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol + Phosphorylation 8617742
GRM1 Q13255 P97772 Receptor Membrane HOMER2 Q9NSB8 Q9QWW1 Adapter Cytosol 0 Binding 9808458
CALM3 P62158 P62204 Activator Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 12821674
PTK2B Q14289 Q9QVP9 Kinase Cytosol GRB2 P62993 Q60631 Adapter Cytosol + Binding 10329689
PTK2B Q14289 Q9QVP9 Kinase Cytosol GRB2 P62993 Q60631 Adapter Cytosol + Binding 9560226
VAV1 P15498 P27870 GEF Cytosol RAC1 P63000 P63001 GTPase Cytosol + GEF 8990121
VAV1 P15498 P27870 GEF Cytosol RAC1 P63000 P63001 GTPase Cytosol + GEF 11790798
KCNIP1 Q9NZI2 Q9JJ57 Adapter Cytosol KCND3 Q9UK17 Q9Z0V1 Channel Membrane 0 Binding 15356203
CALCIUM NA NA Messenger Cytosol SYN1 P17600 O88935 Vesicle Vesicles + Binding 9463376
ROCK2 O75116 P70336 Kinase Cytosol DPYSL2 Q16555 O08553 Activator Cytosol + Phosphorylation 10818093
DLG4 P78352 Q62108 Adapter Cytosol MAP1A P78559 Q9QYR6 Activator Cytosol + Binding 9786987
PRKACA P17612 P05132 Kinase Cytosol PPP1R9B Q96SB3 Q6R891 Cytoskeleton Cytosol + Phosphorylation 12417592
CNR2 P34972 P47936 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 15082510
SRC P12931 P05480 Kinase Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 7505438
SRC P12931 P05480 Kinase Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 9539797
SOD1 P00441 P08228 Dismutase Cytosol H2O2 NA NA Messenger Cytosol + Generating 3459147
APS O14492 Q9JID9 Adapter Cytosol VAV1 P15498 P27870 GEF Cytosol + Binding 12400014
GRB2 P62993 Q60631 Adapter Cytosol WASF1 Q92558 Q8R5H6 Activator Cytosol + Binding 9307968
INADL Q8NI35 Q63ZW7 Adapter Cytosol CNTNAP1 P78357 O54991 CellAdhesion Membrane 0 Binding 9647694
MAPK8 P45983 Q91Y86 Kinase Nucleus NUP214 P35658 NA Cytoskeleton Nucleus 0 Phosphorylation 16061693
GRIN2A Q12879 P35436 Receptor Membrane PLCG1 P19174 Q62077 Phospholipase Cytosol + Binding 9231720
ANK1 P16157 Q02357 Cytoskeleton Cytosol SPTBN2 O15020 NA Cytoskeleton Cytosol 0 Binding 2933395
ANK1 P16157 Q02357 Cytoskeleton Cytosol SPTBN2 O15020 NA Cytoskeleton Cytosol 0 Binding 11086001
ANK1 P16157 Q02357 Cytoskeleton Cytosol SPTBN2 O15020 NA Cytoskeleton Cytosol 0 Binding 7621818
CRK P46108 Q64010 Adapter Cytosol PXN P49023 Q8VI36 Adapter Cytosol 0 Binding 8662907
CRK P46108 Q64010 Adapter Cytosol PXN P49023 Q8VI36 Adapter Cytosol 0 Binding 10329689
SH3KBP1 Q96B97 Q8R550 Phosphatase Cytosol RBP1 P09455 Q00915 Receptor Membrane _ Dephosphorylation 11564708
MAPK8 P45983 Q91Y86 Kinase Nucleus ATF2 P15336 P16951 TF Nucleus + Phosphorylation 9407028
MAPK8 P45983 Q91Y86 Kinase Nucleus ATF2 P15336 P16951 TF Nucleus + Phosphorylation 7824938
CAMKK2 Q96RR4 Q8C078 Kinase Cytosol AKT1 P31749 P31750 Kinase Cytosol + Phosphorylation 9859994
PRKACA P17612 P05132 Kinase Cytosol NFKB1 P19838 P25799 TF Nucleus + Phosphorylation 15197457
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol TP53BP1 Q12888 P70399 TF Nucleus + Phosphorylation 9050839
PRKACA P17612 P05132 Kinase Cytosol TP53BP1 Q12888 P70399 TF Nucleus + Phosphorylation 9050839
MAP2 P11137 P20357 Cytoskeleton Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol 0 Binding 11278895
PRKCA P17252 P20444 Kinase Cytosol NFASC O94856 Q810U3 CellAdhesion Membrane _ Phosphorylation 8999969
CDH2 P19022 P15116 CellAdhesion Membrane CTNND2 Q9UQB3 O35927 Adapter Cytosol + Binding 12835311
LYN P07948 P25911 Kinase Cytosol PLCG1 P19174 Q62077 Phospholipase Cytosol + Phosphorylation 7682059
ERBB2 P04626 P70424 Receptor Membrane DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 10839362
ERBB2 P04626 P70424 Receptor Membrane DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 11279080
ERBB2 P04626 P70424 Receptor Membrane DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 10725395
ERBB2 P04626 P70424 Receptor Membrane DLG3 Q92796 P70175 Adapter Cytosol 0 Binding 10725395
ERBB2 P04626 P70424 Receptor Membrane DLG2 Q15700 Q91XM9 Adapter Cytosol 0 Binding 10725395
PTPRA P18433 P18052 Phosphatase Cytosol SRC P12931 P05480 Kinase Cytosol + Dephosphorylation 9535845
MAPK14 Q16539 P47811 Kinase Cytosol CARD14 Q9BXL6 Q99KF0 Kinase Cytosol + Phosphorylation 9155018
MAPK14 Q16539 P47811 Kinase Cytosol CARD14 Q9BXL6 Q99KF0 Kinase Cytosol + Phosphorylation 9155017
PTK2 Q05397 P34152 Kinase Cytosol IRS1 P35568 P35569 Adapter Cytosol 0 Binding 9822703
SRP54 P61011 P14576 Adapter Ribosomes NASCENTCHAIN NA NA Peptide Ribosomes + Binding 12913112
SRP54 P61011 P14576 Adapter Ribosomes NASCENTCHAIN NA NA Peptide Ribosomes + Binding 2502718
BCAP31 P51572 Q61335 Adapter ER BCL2L1 Q07817 Q64373 Bcl2Family Mitochondria + Binding 9334338
KNS2 Q07866 O88447 Cytoskeleton Cytosol MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol 0 Binding 11238452
OPRK1 P41145 P33534 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 15082510
FYN P06241 P39688 Kinase Cytosol PLCG1 P19174 Q62077 Phospholipase Cytosol + Phosphorylation 7682059
ACTB P60709 P60710 Cytoskeleton Cytosol IQGAP1 P46940 Q9JKF1 GAP Cytosol 0 Binding 11809768
ACTB P60709 P60710 Cytoskeleton Cytosol IQGAP1 P46940 Q9JKF1 GAP Cytosol 0 Binding 9199170
CALM3 P62158 P62204 Activator Cytosol UNC13B O14795 Q9Z1N9 Vesicle Vesicles + Binding 15294163
CALM3 P62158 P62204 Activator Cytosol UNC13B O14795 Q9Z1N9 Vesicle Vesicles + Binding 12917685
NTRK1 P04629 NA Receptor Membrane PIK3CA P42336 P42337 Kinase Cytosol + Binding 8226808
PRKACA P17612 P05132 Kinase Cytosol PPP1R1B Q9UD71 Q60829 Inhibitor Cytosol + Phosphorylation 3339428
PRKACA P17612 P05132 Kinase Cytosol PPP1R1B Q9UD71 Q60829 Inhibitor Cytosol + Phosphorylation 6296685
PRKACA P17612 P05132 Kinase Cytosol PPP1R1B Q9UD71 Q60829 Inhibitor Cytosol + Phosphorylation 6319628
FBXW7 Q969H0 Q8VBV4 Ubiquitinase Cytosol MYC P01106 P01108 TF Nucleus _ Ubiquitination 16023596
PRKACA P17612 P05132 Kinase Cytosol PPP1R1A Q13522 Q9ERT9 Inhibitor Cytosol _ Phosphorylation 8611507
MAPK8 P45983 Q91Y86 Kinase Nucleus NFATC1 O95644 O88942 TF Nucleus + Phosphorylation 15743762
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol SRC P12931 P05480 Kinase Cytosol _ Ubiquitination 11448952
CARM1 Q86X55 Q9WVG6 TF Nucleus CTNNB1 P35222 Q02248 TF Cytosol + Binding 11983685
YWHAH Q04917 P68510 Adapter Cytosol RAF1 P04049 Q99N57 Kinase Cytosol _ Binding 12801936
CAMK2A Q9UQM7 P11798 Kinase Cytosol DLG1 Q12959 Q811D0 Adapter Cytosol + Phosphorylation 12933808
CAMK2A Q9UQM7 P11798 Kinase Cytosol DLG1 Q12959 Q811D0 Adapter Cytosol + Phosphorylation 15044483
BIRC4 P98170 Q60989 Inhibitor Cytosol CASP9 P55211 NA Protease Cytosol _ Binding 12620238
BIRC4 P98170 Q60989 Inhibitor Cytosol CASP9 P55211 NA Protease Cytosol _ Binding 10508158
BIRC4 P98170 Q60989 Inhibitor Cytosol CASP7 P55210 P97864 Protease Cytosol _ Binding 9230442
BIRC4 P98170 Q60989 Inhibitor Cytosol CASP7 P55210 P97864 Protease Cytosol _ Binding 10508158
BIRC4 P98170 Q60989 Inhibitor Cytosol CASP3 P42574 P70677 Protease Cytosol _ Binding 9230442
BIRC4 P98170 Q60989 Inhibitor Cytosol CASP3 P42574 P70677 Protease Cytosol _ Binding 10508158
PIP2 NA NA Lipid Cytosol CASP9 P55211 NA Protease Cytosol _ Binding 11042212
PIP2 NA NA Lipid Cytosol CASP8 Q14790 O89110 Protease Cytosol _ Binding 11042212
AKT1 P31749 P31750 Kinase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria _ Phosphorylation 9346240
AKT1 P31749 P31750 Kinase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria _ Phosphorylation 9381178
AKT1 P31749 P31750 Kinase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria _ Phosphorylation 10383455
PIP2 NA NA Lipid Cytosol CASP3 P42574 P70677 Protease Cytosol _ Binding 11042212
PPP2R5C Q13362 Q60996 Phosphatase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria + Dephosphorylation 11222372
NCK1 P16333 NA Adapter Cytosol ABL1 P00519 P00520 Kinase Cytosol + Phosphorylation 10488144
VAV1 P15498 P27870 GEF Cytosol CDC42 P60953 P60766 GTPase Cytosol + GEF 8994827
VAV1 P15498 P27870 GEF Cytosol CDC42 P60953 P60766 GTPase Cytosol + GEF 9032261
S60 NA NA Ribosome Ribosomes SEC61A1 P61619 P61620 Channel ER 0 Binding 11036067
CAMK2A Q9UQM7 P11798 Kinase Cytosol CHN1 P15882 Q91V57 Adapter Cytosol _ Phosphorylation 12531901
SRF P11831 NA TF Nucleus SRE NA NA DNA Nucleus 0 Binding 3203386
SRF P11831 NA TF Nucleus SRE NA NA DNA Nucleus 0 Binding 2108863
WASF1 Q92558 Q8R5H6 Activator Cytosol ITSN1 Q15811 Q9Z0R4 Adapter Vesicles + Binding 11584276
NRCAM Q92823 Q810U4 CellAdhesion Membrane ANK1 P16157 Q02357 Cytoskeleton Cytosol 0 Binding 7961622
C20ORF11 Q9NWU2 NA Adapter Cytosol RANBP9 Q96S59 P69566 Adapter Cytosol 0 Binding 12559565
SRC P12931 P05480 Kinase Cytosol GLRA1 P23415 Q64018 Receptor Membrane + Phosphorylation 11882681
EIF4A1 P60842 P60843 Ribosome Ribosomes mRNA NA NA RNA Ribosomes 0 Binding 3707129
EIF4A1 P60842 P60843 Ribosome Ribosomes mRNA NA NA RNA Ribosomes 0 Binding 6579543
TRADD Q15628 NA Adapter Cytosol RIPK1 Q13546 Q60855 Kinase Cytosol + Binding 8612133
CTTN Q14247 Q60598 Cytoskeleton Cytosol ARPC1B O15143 Q9WV32 Cytoskeleton Cytosol + Binding 11018051
EIF2S1 P05198 Q6ZWX6 Ribosome Ribosomes tRNA NA NA RNA Ribosomes 0 Binding 863906
EIF2S1 P05198 Q6ZWX6 Ribosome Ribosomes tRNA NA NA RNA Ribosomes 0 Binding 833127
PDE3A Q14432 Q9Z0X4 PDE Cytosol CAMP P49913 P51437 Messenger Cytosol _ PDE 8395509
VRK1 Q99986 Q80X41 Kinase Cytosol ATF2 P15336 P16951 TF Nucleus + Phosphorylation 15105425
OPRK1 P41145 P33534 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 15082510
L1CAM P32004 P11627 CellAdhesion Membrane ANK1 P16157 Q02357 Cytoskeleton Cytosol 0 Binding 7961622
L1CAM P32004 P11627 CellAdhesion Membrane ANK1 P16157 Q02357 Cytoskeleton Cytosol 0 Binding 12070130
DGUOK Q16854 Q9QX60 Kinase Cytosol DAG NA NA Lipid Cytosol _ Phosphorylation 11287665
PRKACA P17612 P05132 Kinase Cytosol FLNA P21333 Q8BTM8 Cytoskeleton Cytosol + Phosphorylation 15228085
PRKACA P17612 P05132 Kinase Cytosol FLNA P21333 Q8BTM8 Cytoskeleton Cytosol + Phosphorylation 207708
COX5B P10606 P19536 DualRole Mitochondria ITPR1 Q14643 P11881 Channel ER + Binding 14608362
GDI1 P31150 P50396 Inhibitor Cytosol RAB3A P20336 P63011 GTPase Vesicles _ Binding 9252412
NF1 P21359 Q04690 GAP Cytosol NRAS P01111 P08556 GTPase Cytosol _ Binding 2116237
NF1 P21359 Q04690 GAP Cytosol NRAS P01111 P08556 GTPase Cytosol _ Binding 2121370
INADL Q8NI35 Q63ZW7 Adapter Cytosol NLGN1 Q8N2Q7 Q99K10 CellAdhesion Membrane 0 Binding 9647694
PRKACA P17612 P05132 Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 2875459
PRKACA P17612 P05132 Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 2885756
GCC1 Q96CN9 Q9D4H2 Adapter Cytosol GRM7 Q14831 Q68ED2 Receptor Membrane 0 Binding 11891216
AKT1 P31749 P31750 Kinase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol _ Phosphorylation 10576742
CDK5 Q00535 P49615 Kinase Cytosol STXBP1 P61764 O08599 Vesicle Vesicles _ Phosphorylation 9478941
CDK5 Q00535 P49615 Kinase Cytosol STXBP1 P61764 O08599 Vesicle Vesicles _ Phosphorylation 9933594
NE NA NA Ligand Extracellular ADRB2 P07550 P18762 Receptor Membrane + Binding 15102960
NE NA NA Ligand Extracellular ADRB2 P07550 P18762 Receptor Membrane + Binding 3016604
NE NA NA Ligand Extracellular ADRB2 P07550 P18762 Receptor Membrane + Binding 6324206
CERK Q8TCT0 Q8K4Q7 Kinase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Phosphorylation 7477354
STON2 Q8WXE9 Q8BZ60 Adapter Vesicles ITSN1 Q15811 Q9Z0R4 Adapter Vesicles 0 Binding 11381094
FHL2 Q14192 O70433 TF Nucleus FOS P01100 P01101 TF Nucleus + Binding 12644711
SYP P08247 Q62277 Vesicle Vesicles VAMP1 P23763 Q62442 Vesicle Vesicles 0 Binding 12485399
CABP1 Q9NZU7 Q9JLK7 Inhibitor Cytosol CAMK2A Q9UQM7 P11798 Kinase Cytosol _ Binding 9920909
CSK P41240 P41241 Kinase Cytosol PTK2 Q05397 P34152 Kinase Cytosol + Phosphorylation 9890993
TRAF2 Q12933 P39429 Adapter Cytosol MAP3K14 Q99558 Q9WUL6 Kinase Cytosol 0 Binding 9020361
CLTA P09496 O08585 Vesicle Vesicles CALM3 P62158 P62204 Activator Cytosol 0 Binding 7836475
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol ANK1 P16157 Q02357 Cytoskeleton Cytosol _ Phosphorylation 2933395
LCK P06239 P06240 Kinase Cytosol PLCG1 P19174 Q62077 Phospholipase Cytosol + Phosphorylation 7682059
MAPK1 P28482 P63085 Kinase Cytosol MAPT P10636 P10637 Activator Cytosol + Phosphorylation 7488031
MAPK1 P28482 P63085 Kinase Cytosol MAPT P10636 P10637 Activator Cytosol + Phosphorylation 8166686
PRKACA P17612 P05132 Kinase Cytosol ITPR1 Q14643 P11881 Channel ER _ Phosphorylation 2847175
PRKACA P17612 P05132 Kinase Cytosol ITPR1 Q14643 P11881 Channel ER _ Phosphorylation 1847804
CDC42 P60953 P60766 GTPase Cytosol MAP3K10 Q02779 NA Kinase Cytosol + Binding 10799501
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol TBR1 Q16650 Q64336 TF Nucleus + Binding 10749215
BCL2L11 O43521 O54918 Bcl2Family Mitochondria BAX Q07812 Q07813 Bcl2Family Mitochondria + Binding 11301022
MAPK1 P28482 P63085 Kinase Cytosol NEFH P12036 P19246 Cytoskeleton Cytosol _ Phosphorylation 9592082
DRD3 P35462 P30728 Receptor Membrane GRB2 P62993 Q60631 Adapter Cytosol + Binding 11384839
CASP8 Q14790 O89110 Protease Cytosol CASP3 P42574 P70677 Protease Cytosol + Cleavage 8962078
HCK P08631 P08103 Kinase Cytosol PLCG1 P19174 Q62077 Phospholipase Cytosol + Phosphorylation 7682059
PPP3R1 P63098 Q63810 Phosphatase Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Dephosphorylation 7514273
MAPK1 P28482 P63085 Kinase Cytosol NEF3 P07197 P08553 Cytoskeleton Cytosol _ Phosphorylation 9592082
PSD3 Q9NYI0 NA GEF Cytosol ARF1 P84077 P84078 GTPase Vesicles + GEF 11342560
SODIUM NA NA Ion Cytosol KCNJ3 P48549 P63250 Channel Membrane + Binding 8804710
PIP5K2A P48426 O70172 Kinase Cytosol PIP2 NA NA Lipid Cytosol + Phosphorylation 7852364
ACTB P60709 P60710 Cytoskeleton Cytosol VCL P18206 Q64727 Cytoskeleton Cytosol 0 Binding 6789327
MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol RASGRF1 Q13972 P27671 GEF Cytosol + Binding 12024021
ARHGAP1 Q07960 NA GTPase Cytosol PIP5K2A P48426 O70172 Kinase Cytosol + Binding 8868471
WNT6 Q9Y6F9 P22727 Ligand Extracellular FZD1 Q9UP38 O70421 Receptor Membrane + Binding 8717036
WNT6 Q9Y6F9 P22727 Ligand Extracellular FZD1 Q9UP38 O70421 Receptor Membrane + Binding 12857724
DUSP10 Q9Y6W6 Q9ESS0 Phosphatase Cytosol MAPK8 P45983 Q91Y86 Kinase Nucleus _ Dephosphorylation 11790549
TUBA3 Q71U36 NA Cytoskeleton Cytosol GABARAPL3 Q9BY60 NA Adapter Cytosol 0 Binding 9892355
TUBA3 Q71U36 NA Cytoskeleton Cytosol GABARAPL3 Q9BY60 NA Adapter Cytosol 0 Binding 11779480
PTK2B Q14289 Q9QVP9 Kinase Cytosol SRC P12931 P05480 Kinase Cytosol + Binding 10329689
PTK2B Q14289 Q9QVP9 Kinase Cytosol SRC P12931 P05480 Kinase Cytosol + Binding 9560226
PTK2B Q14289 Q9QVP9 Kinase Cytosol SRC P12931 P05480 Kinase Cytosol + Binding 8849729
PTK2B Q14289 Q9QVP9 Kinase Cytosol SRC P12931 P05480 Kinase Cytosol + Binding 11274221
CREB1 P16220 Q01147 TF Nucleus CREBBP Q92793 P45481 TF Nucleus + Binding 8004670
CREB1 P16220 Q01147 TF Nucleus CREBBP Q92793 P45481 TF Nucleus + Binding 7870178
CREB1 P16220 Q01147 TF Nucleus CREBBP Q92793 P45481 TF Nucleus + Binding 7870179
CREB1 P16220 Q01147 TF Nucleus CREBBP Q92793 P45481 TF Nucleus + Binding 8413673
RPS6KB1 P23443 Q8BSK8 Kinase Cytosol S6 NA NA Adapter Ribosomes + Phosphorylation 6325456
PPP1R14A Q96A00 Q91VC7 Inhibitor Cytosol PPP1R12B O60237 Q8BG95 Phosphatase Cytosol _ Binding 12495628
PDPK1 O15530 Q9Z2A0 Kinase Cytosol AKT1 P31749 P31750 Kinase Cytosol + Phosphorylation 9094314
ADRA2A P08913 Q01338 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 1849000
VDAC2 P45880 Q60930 Channel Mitochondria BAK1 Q16611 O08734 Bcl2Family Mitochondria _ Binding 12881569
MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol MAP3K10 Q02779 NA Kinase Cytosol + Binding 9733513
FOS P01100 P01101 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 1827203
FOS P01100 P01101 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 12192032
PRKACA P17612 P05132 Kinase Cytosol RPH3A Q9Y2J0 P47708 Vesicle Vesicles + Phosphorylation 7891174
PRKACA P17612 P05132 Kinase Cytosol RPH3A Q9Y2J0 P47708 Vesicle Vesicles + Phosphorylation 9425005
dATP NA NA Messenger Cytosol APAF1 O14727 O88879 Adapter Cytosol + Binding 10364241
dATP NA NA Messenger Cytosol APAF1 O14727 O88879 Adapter Cytosol + Binding 9390557
CTNNB1 P35222 Q02248 TF Cytosol PSEN1 P49768 P49769 Protease Membrane 0 Binding 9223106
PPP1CC P36873 P63087 Phosphatase Cytosol BCL2 P10415 P10417 Bcl2Family Mitochondria + Dephosphorylation 12051739
PAF Q15004 Q9CQX4 Ligand Extracellular PTAFR P25105 Q62035 Receptor Membrane + Binding 1323312
PAF Q15004 Q9CQX4 Ligand Extracellular PTAFR P25105 Q62035 Receptor Membrane + Binding 12106349
PAF Q15004 Q9CQX4 Ligand Extracellular PTAFR P25105 Q62035 Receptor Membrane + Binding 2831903
PAF Q15004 Q9CQX4 Ligand Extracellular PTAFR P25105 Q62035 Receptor Membrane + Binding 1846231
PRKACA P17612 P05132 Kinase Cytosol MAPT P10636 P10637 Activator Cytosol + Phosphorylation 6412713
PRKACA P17612 P05132 Kinase Cytosol MAPT P10636 P10637 Activator Cytosol + Phosphorylation 1730702
SH3KBP1 Q96B97 Q8R550 Phosphatase Cytosol ACTN3 Q08043 O88990 Cytoskeletal Cytosol _ Dephosphorylation 15070900
SUMO1 P63165 P63166 Sumo Cytosol JUN P05412 P05627 TF Nucleus _ Sumolation 16055710
SUMO1 P63165 P63166 Sumo Cytosol JUN P05412 P05627 TF Nucleus _ Sumolation 10788439
PTPN11 Q06124 P35235 Phosphatase Cytosol GRB2 P62993 Q60631 Adapter Cytosol + Binding 7523381
PTPN11 Q06124 P35235 Phosphatase Cytosol GRB2 P62993 Q60631 Adapter Cytosol + Binding 7522233
PRKACA P17612 P05132 Kinase Cytosol MAP2 P11137 P20357 Cytoskeleton Cytosol + Phosphorylation 2561875
PRKACA P17612 P05132 Kinase Cytosol MAP2 P11137 P20357 Cytoskeleton Cytosol + Phosphorylation 12369833
PRKACA P17612 P05132 Kinase Cytosol MAP2 P11137 P20357 Cytoskeleton Cytosol + Phosphorylation 8391085
AXIN1 O15169 O35625 Adapter Cytosol MAP3K4 Q9Y6R4 O08648 Kinase Cytosol + Binding 12878610
AXIN1 O15169 O35625 Adapter Cytosol MAP3K1 Q13233 P53349 Kinase Cytosol + Binding 11408485
AXIN1 O15169 O35625 Adapter Cytosol MAP3K1 Q13233 P53349 Kinase Cytosol + Binding 12878610
TNF P01375 P06804 Ligand Extracellular TNFRSF1A P19438 P25118 Receptor Membrane + Binding 8397073
CAMK1 Q14012 Q91YS8 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Phosphorylation 3118371
FKBP1A P62942 P26883 Adapter Cytosol RYR1 P21817 NA Channel ER 0 Binding 8521476
RBP1 P09455 Q00915 Receptor Membrane SHC1 P29353 P98083 Adapter Cytosol 0 Binding 11313948
RBP1 P09455 Q00915 Receptor Membrane SHC1 P29353 P98083 Adapter Cytosol 0 Binding 10995764
RBP1 P09455 Q00915 Receptor Membrane SHC1 P29353 P98083 Adapter Cytosol 0 Binding 12242309
GRIN2A Q12879 P35436 Receptor Membrane SSCAM NA NA Adapter Cytosol 0 Binding 9694864
APAF1 O14727 O88879 Adapter Cytosol CASP9 P55211 NA Protease Cytosol + Cleavage 10617566
APAF1 O14727 O88879 Adapter Cytosol CASP9 P55211 NA Protease Cytosol + Cleavage 9651578
APAF1 O14727 O88879 Adapter Cytosol CASP9 P55211 NA Protease Cytosol + Cleavage 9390557
APAF1 O14727 O88879 Adapter Cytosol CASP9 P55211 NA Protease Cytosol + Cleavage 9837928
KCND1 Q9NSA2 Q03719 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 11723117
KCND1 Q9NSA2 Q03719 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 9437018
ADRA2A P08913 Q01338 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 1849000
DRD2 P14416 P61168 Receptor Membrane GNAZ P19086 O70443 Gprotein Cytosol + Binding 10384262
GRIK1 P39086 Q60934 Channel Membrane GCC1 Q96CN9 Q9D4H2 Adapter Cytosol 0 Binding 12597860
GRIK1 P39086 Q60934 Channel Membrane GCC1 Q96CN9 Q9D4H2 Adapter Cytosol 0 Binding 11891216
DRD2 P14416 P61168 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 12869650
IQGAP1 P46940 Q9JKF1 GAP Cytosol CDC42 P60953 P60766 GTPase Cytosol 0 Binding 8798539
IQGAP1 P46940 Q9JKF1 GAP Cytosol CDC42 P60953 P60766 GTPase Cytosol 0 Binding 9199170
RAP1GA1 P47736 NA GAP Cytosol RAP1A P62834 P62835 GTPase Cytosol _ GAP 15141215
CALM3 P62158 P62204 Activator Cytosol MARCKS P29966 P26645 Adapter Cytosol _ Binding 1560845
CALM3 P62158 P62204 Activator Cytosol MARCKS P29966 P26645 Adapter Cytosol _ Binding 2557349
SNAP25 P60880 P60879 Vesicle Vesicles CAV1 Q03135 P49817 Adapter Cytosol 0 Binding 11883949
RSN P30622 Q922J3 Adapter Cytosol IQGAP1 P46940 Q9JKF1 GAP Cytosol 0 Binding 12361581
ADRA2A P08913 Q01338 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 1849000
PTPN5 P54829 P54830 Phosphatase Cytosol MAPK1 P28482 P63085 Kinase Cytosol _ Dephosphorylation 9857190
PRKACA P17612 P05132 Kinase Cytosol NFATC1 O95644 O88942 TF Nucleus _ Phosphorylation 10611249
DRD2 P14416 P61168 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 1445393
CHRM1 P11229 P12657 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 8196770
CHRM1 P11229 P12657 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 14976183
CHRM1 P11229 P12657 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 1341877
CHRM1 P11229 P12657 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 3110621
CHRM1 P11229 P12657 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 8576109
BAG1 Q99933 Q60739 Adapter Cytosol BCL2 P10415 P10417 Bcl2Family Mitochondria + Binding 8692945
BAG1 Q99933 Q60739 Adapter Cytosol BCL2 P10415 P10417 Bcl2Family Mitochondria + Binding 7834747
MAP3K10 Q02779 NA Kinase Cytosol MAP2K4 P45985 P47809 Kinase Cytosol + Phosphorylation 8702571
GRB2 P62993 Q60631 Adapter Cytosol SH3KBP1 Q96B97 Q8R550 Phosphatase Cytosol 0 Binding 14551136
FOSL2 P15408 P47930 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 1827203
FOSL2 P15408 P47930 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 12192032
CALM3 P62158 P62204 Activator Cytosol CAMK4 Q16566 P08414 Kinase Cytosol + Binding 8340352
RGS19 P49795 Q9CX84 GAP Cytosol GNAQ P50148 P21279 Gprotein Cytosol _ GAP 9012799
PRKCA P17252 P20444 Kinase Cytosol PPP1R14A Q96A00 Q91VC7 Inhibitor Cytosol + Phosphorylation 15003508
PRKCA P17252 P20444 Kinase Cytosol PPP1R14A Q96A00 Q91VC7 Inhibitor Cytosol + Phosphorylation 12495628
EFNB2 P52799 P52800 Receptor Membrane SDC1 P18827 P18828 Receptor Membrane + Phosphorylation 11580899
RIMS1 Q86UR5 Q99NE5 Adapter Vesicles SNAP25 P60880 P60879 Vesicle Vesicles + Binding 11438518
EPN2 O95208 Q8CHU3 Adapter Vesicles ITSN1 Q15811 Q9Z0R4 Adapter Vesicles 0 Binding 10336464
CALCIUM NA NA Messenger Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 8063723
ACTB P60709 P60710 Cytoskeleton Cytosol EPB41 P11171 P48193 Adapter Cytosol 0 Binding 12399578
CSK P41240 P41241 Kinase Cytosol SRC P12931 P05480 Kinase Cytosol _ Binding 14665621
CSK P41240 P41241 Kinase Cytosol SRC P12931 P05480 Kinase Cytosol _ Binding 1383688
CALCIUM NA NA Messenger Cytosol CANX P27824 P35564 Chaperone ER + Binding 1918067
PDGF NA NA Ligand Extracellular PDGFRB P09619 P05622 Receptor Membrane + Binding 2550144
PRKCA P17252 P20444 Kinase Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol _ Phosphorylation 9015864
PRKCA P17252 P20444 Kinase Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol _ Phosphorylation 2211670
PRKCA P17252 P20444 Kinase Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol _ Phosphorylation 9307019
BIRC2 Q13490 Q62210 Inhibitor Cytosol CASP7 P55210 P97864 Protease Cytosol _ Binding 9384571
BIRC2 Q13490 Q62210 Inhibitor Cytosol CASP3 P42574 P70677 Protease Cytosol _ Binding 9384571
ABL1 P00519 P00520 Kinase Cytosol CTNND2 Q9UQB3 O35927 Adapter Cytosol + Phosphorylation 11891774
NTRK2 Q16620 P15209 Receptor Membrane IRS2 Q9Y4H2 P81122 Adapter Cytosol + Phosphorylation 9374521
NTRK2 Q16620 P15209 Receptor Membrane IRS1 P35568 P35569 Adapter Cytosol + Binding 9374521
APBA1 Q02410 NA Vesicle Vesicles CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol 0 Binding 12040031
CNR2 P34972 P47936 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 15082510
MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol MAPK14 Q16539 P47811 Kinase Cytosol + Binding 12024021
CALCIUM NA NA Messenger Cytosol CALR P27797 P14211 Chaperone ER + Binding 3968084
PRKCA P17252 P20444 Kinase Cytosol GRM7 Q14831 Q68ED2 Receptor Membrane + Phosphorylation 10488094
PRKCA P17252 P20444 Kinase Cytosol GRM7 Q14831 Q68ED2 Receptor Membrane + Phosphorylation 12021391
PRKCA P17252 P20444 Kinase Cytosol GRM7 Q14831 Q68ED2 Receptor Membrane + Phosphorylation 11007882
PRKCA P17252 P20444 Kinase Cytosol GRM1 Q13255 P97772 Receptor Membrane + Phosphorylation 15305863
GLUTAMATE NA NA Ligand Extracellular GRIN2A Q12879 P35436 Receptor Membrane + Binding 8768735
SYN1 P17600 O88935 Vesicle Vesicles ACTB P60709 P60710 Cytoskeleton Cytosol + Binding 7849051
PRKACA P17612 P05132 Kinase Cytosol PLCG1 P19174 Q62077 Phospholipase Cytosol _ Phosphorylation 2479646
GNB2L1 P63244 P68040 Adapter Cytosol GRIN2A Q12879 P35436 Receptor Membrane 0 Binding 11943848
CHRM4 P08173 P32211 Receptor Membrane EEF1A2 Q05639 P62631 Elongation Ribosomes + Binding 12048193
L1CAM P32004 P11627 CellAdhesion Membrane VIL2 P15311 P26040 Cytoskeleton Cytosol + Binding 12070130
PRKACA P17612 P05132 Kinase Cytosol RAP1A P62834 P62835 GTPase Cytosol _ Phosphorylation 9867809
PRKACA P17612 P05132 Kinase Cytosol RAP1A P62834 P62835 GTPase Cytosol _ Phosphorylation 8463283
DRD2 P14416 P61168 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 2898118
DRD2 P14416 P61168 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 1445393
DRD2 P14416 P61168 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 10384262
PPP3R1 P63098 Q63810 Phosphatase Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol _ Dephosphorylation 2987415
PRKCA P17252 P20444 Kinase Cytosol EIF4E P06730 P63073 Adapter Ribosomes + Phosphorylation 2355012
PRKCA P17252 P20444 Kinase Cytosol EIF4E P06730 P63073 Adapter Ribosomes + Phosphorylation 1911648
APS O14492 Q9JID9 Adapter Cytosol GRB2 P62993 Q60631 Adapter Cytosol 0 Binding 9856458
TNIK Q9UKE5 P83510 Kinase Cytosol GSN P06396 P13020 Cytoskeleton Cytosol _ Phosphorylation 10521462
FKBP1A P62942 P26883 Adapter Cytosol PPP3R1 P63098 Q63810 Phosphatase Cytosol + Binding 8521476
FKBP1A P62942 P26883 Adapter Cytosol PPP3R1 P63098 Q63810 Phosphatase Cytosol + Binding 1715244
FKBP1A P62942 P26883 Adapter Cytosol PPP3R1 P63098 Q63810 Phosphatase Cytosol + Binding 9356420
FKBP1A P62942 P26883 Adapter Cytosol PPP3R1 P63098 Q63810 Phosphatase Cytosol + Binding 12514224
PROKR1 Q8TCW9 Q9JKL1 Kinase Cytosol EIF2S1 P05198 Q6ZWX6 Ribosome Ribosomes _ Phosphorylation 3479429
PROKR1 Q8TCW9 Q9JKL1 Kinase Cytosol EIF2S1 P05198 Q6ZWX6 Ribosome Ribosomes _ Phosphorylation 10866685
PROKR1 Q8TCW9 Q9JKL1 Kinase Cytosol EIF2S1 P05198 Q6ZWX6 Ribosome Ribosomes _ Phosphorylation 7890757
PROKR1 Q8TCW9 Q9JKL1 Kinase Cytosol EIF2S1 P05198 Q6ZWX6 Ribosome Ribosomes _ Phosphorylation 11555640
BCL2L11 O43521 O54918 Bcl2Family Mitochondria BCL2 P10415 P10417 Bcl2Family Mitochondria _ Binding 11301022
KCNA2 P16389 P63141 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 2555158
GRASP Q7Z6J2 Q9JJA9 Adapter Cytosol DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 12586822
RBP1 P09455 Q00915 Receptor Membrane GRB2 P62993 Q60631 Adapter Cytosol + Binding 10995764
ACTB P60709 P60710 Cytoskeleton Cytosol PPP1R9A Q9ULJ8 NA Adapter Cytosol 0 Binding 9362513
PAK1 Q13153 O88643 Kinase Cytosol ARHGEF7 Q14155 Q9ES28 GEF Cytosol + Binding 9659915
PAK1 Q13153 O88643 Kinase Cytosol ARHGEF7 Q14155 Q9ES28 GEF Cytosol + Binding 11096073
PAK1 Q13153 O88643 Kinase Cytosol ARHGEF7 Q14155 Q9ES28 GEF Cytosol + Binding 9726964
PRKACA P17612 P05132 Kinase Cytosol ADRB2 P07550 P18762 Receptor Membrane _ Phosphorylation 2987243
EIF3S1 O75822 Q66JS6 Ribosome Ribosomes mRNA NA NA RNA Ribosomes 0 Binding 6906354
MAPK1 P28482 P63085 Kinase Cytosol PLAA Q9Y263 P27612 Phospholipase Cytosol + Phosphorylation 8381049
CTNND2 Q9UQB3 O35927 Adapter Cytosol CTTN Q14247 Q60598 Cytoskeleton Cytosol + Binding 12835311
F2RL1 P55085 P55086 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 7937743
F2RL1 P55085 P55086 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 8615752
F2RL1 P55085 P55086 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 9349532
F2RL1 P55085 P55086 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 9349532
YWHAH Q04917 P68510 Adapter Cytosol RIN1 Q13671 Q921Q7 Activator Cytosol _ Binding 11784866
GRB2 P62993 Q60631 Adapter Cytosol SF1 Q15637 Q64213 Adapter Cytosol + Binding 12112020
CNR2 P34972 P47936 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 15082510
CALM3 P62158 P62204 Activator Cytosol RAC1 P63000 P63001 Adapter Cytosol + Binding 9813038
CALM3 P62158 P62204 Activator Cytosol RAC1 P63000 P63001 Adapter Cytosol + Binding 8918462
DLG4 P78352 Q62108 Adapter Cytosol KCNJ4 P48050 P52189 Channel Membrane 0 Binding 8893032
PRKACA P17612 P05132 Kinase Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol _ Phosphorylation 8657310
PRKACA P17612 P05132 Kinase Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol _ Phosphorylation 9660757
PPM1F P49593 Q8CGA0 Phosphatase Cytosol CAMK2A Q9UQM7 P11798 Kinase Cytosol _ Dephosphorylation 10814834
DLG4 P78352 Q62108 Adapter Cytosol KCNJ2 P63252 P35561 Channel Membrane 0 Binding 8893032
GNB2 P62879 P62880 Gprotein Cytosol ADRBK1 P25098 Q99MK8 Kinase Cytosol + Binding 1325672
GNB2 P62879 P62880 Gprotein Cytosol ADRBK1 P25098 Q99MK8 Kinase Cytosol + Binding 1962211
GNB2 P62879 P62880 Gprotein Cytosol ADRBK1 P25098 Q99MK8 Kinase Cytosol + Binding 8416978
PPP2R5C Q13362 Q60996 Phosphatase Cytosol EIF4EBP3 O60516 Q80VV3 TF Nucleus + Dephosphorylation 10200280
RIMS1 Q86UR5 Q99NE5 Adapter Vesicles RAPGEF4 Q8WZA2 Q9EQZ6 GEF Cytosol 0 Binding 11056535
SRC P12931 P05480 Kinase Cytosol GRIN2A Q12879 P35436 Receptor Membrane + Phosphorylation 11677266
SRC P12931 P05480 Kinase Cytosol GRIN2A Q12879 P35436 Receptor Membrane + Phosphorylation 10846184
SRC P12931 P05480 Kinase Cytosol BCAR1 P56945 Q61140 Adapter Cytosol + Phosphorylation 8070403
EIF4G2 P78344 Q62448 Ribosome Ribosomes EIF4E P06730 P63073 Adapter Ribosomes 0 Binding 10944120
UNC13B O14795 Q9Z1N9 Vesicle Vesicles STX3 Q13277 Q64704 Vesicle Vesicles + Binding 8999968
CTNNB1 P35222 Q02248 TF Cytosol LEF1 Q9UJU2 P27782 TF Nucleus + Binding 8892228
CTNNB1 P35222 Q02248 TF Cytosol LEF1 Q9UJU2 P27782 TF Nucleus + Binding 8757136
EIF4A1 P60842 P60843 Ribosome Ribosomes EIF4G2 P78344 Q62448 Ribosome Ribosomes 0 Binding 9372926
EIF4A1 P60842 P60843 Ribosome Ribosomes EIF4G2 P78344 Q62448 Ribosome Ribosomes 0 Binding 10480875
ANK1 P16157 Q02357 Cytoskeleton Cytosol ITPR1 Q14643 P11881 Channel ER 0 Binding 8384211
PXN P49023 Q8VI36 Adapter Cytosol PTK2 Q05397 P34152 Kinase Cytosol 0 Binding 10764815
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol NFATC1 O95644 O88942 TF Nucleus _ Phosphorylation 15121840
OPRD1 P41143 P32300 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 15082510
PIN1 Q13526 Q9QUR7 TF Nucleus FOS P01100 P01101 TF Nucleus + Binding 16123044
RIMS1 Q86UR5 Q99NE5 Adapter Vesicles RAB3A P20336 P63011 GTPase Vesicles + Binding 9252191
RIMS1 Q86UR5 Q99NE5 Adapter Vesicles RAB3A P20336 P63011 GTPase Vesicles + Binding 11431472
ACTB P60709 P60710 Cytoskeleton Cytosol ACTN3 Q08043 O88990 Cytoskeleton Cytosol 0 Binding 1107334
CNKSR1 Q969H4 NA Kinase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Binding 9115393
CRK P46108 Q64010 Adapter Cytosol SHC1 P29353 P98083 Adapter Cytosol 0 Binding 8662907
PRKACA P17612 P05132 Kinase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol _ Phosphorylation 10862777
PRKACA P17612 P05132 Kinase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol _ Phosphorylation 7935389
PRKACA P17612 P05132 Kinase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol _ Phosphorylation 9001246
EGFR P00533 Q01279 Receptor Membrane PLCG1 P19174 Q62077 Phospholipase Cytosol + Phosphorylation 2472219
MAP2 P11137 P20357 Cytoskeleton Cytosol CACNA1C Q13936 Q01815 Channel Membrane 0 Binding 10514522
CASP3 P42574 P70677 Protease Cytosol PRKDC P78527 P97313 Kinase Nucleus _ Cleavage 8798786
IRS1 P35568 P35569 Adapter Cytosol GRB2 P62993 Q60631 Adapter Cytosol + Binding 8491186
IRS1 P35568 P35569 Adapter Cytosol GRB2 P62993 Q60631 Adapter Cytosol + Binding 8114695
IRS1 P35568 P35569 Adapter Cytosol GRB2 P62993 Q60631 Adapter Cytosol + Binding 8196603
IRS1 P35568 P35569 Adapter Cytosol GRB2 P62993 Q60631 Adapter Cytosol + Binding 8265614
ACTN3 Q08043 O88990 Cytoskeletal Cytosol PLD2 O14939 P97813 Phospholipase Cytosol 0 Binding 10801846
GRB2 P62993 Q60631 Adapter Cytosol PTPRA P18433 P18052 Phosphatase Cytosol _ Binding 8670803
NGFR P08138 Q9Z0W1 Receptor Membrane TRAF6 Q9Y4K3 P70196 Adapter Cytosol + Binding 10514511
NGFR P08138 Q9Z0W1 Receptor Membrane TRAF4 Q9BUZ4 Q61382 Adapter Cytosol + Binding 10514511
NGFR P08138 Q9Z0W1 Receptor Membrane TRAF2 Q12933 P39429 Adapter Cytosol + Binding 10514511
GPHN Q9NQX3 NA Adapter Membrane GABARAPL3 Q9BY60 NA Adapter Cytosol 0 Binding 10900017
SUMO1 P63165 P63166 Sumo Cytosol TP53BP1 Q12888 P70399 TF Nucleus _ Sumolation 10788439
NFKBIB Q15653 Q60778 Adapter Cytosol NFKB1 P19838 P25799 TF Nucleus _ Binding 8816457
PRKACA P17612 P05132 Kinase Cytosol SNAP25 P60880 P60879 Vesicle Vesicles + Phosphorylation 15269257
RELN P78509 Q60841 Ligand Extracellular ITGB1 P05556 P09055 CellAdhesion Membrane _ Binding 10725376
RELN P78509 Q60841 Ligand Extracellular ITGB1 P05556 P09055 CellAdhesion Membrane _ Binding 10939329
TUBA3 Q71U36 NA Cytoskeleton Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 7505438
GNAZ P19086 O70443 Gprotein Cytosol ADCY5 O95622 P84309 Cyclase Membrane _ Binding 7829508
GNAZ P19086 O70443 Gprotein Cytosol ADCY1 Q08828 O88444 Cyclase Cytosol _ Binding 7829508
FYN P06241 P39688 Kinase Cytosol GRIA1 P42261 P23818 Channel Membrane + Phosphorylation 11677266
PPP1CC P36873 P63087 Phosphatase Cytosol CFL1 P23528 P18760 Cytoskeleton Cytosol + Dephosphorylation 11093160
PPP1R12B O60237 Q8BG95 Phosphatase Cytosol MYO18A Q92614 Q9JMH9 Cytoskeleton Cytosol _ Dephosphorylation 9570949
PPP1R12B O60237 Q8BG95 Phosphatase Cytosol MYO18A Q92614 Q9JMH9 Cytoskeleton Cytosol _ Dephosphorylation 186030
OPRM1 P35372 P42866 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 15082510
SNAP25 P60880 P60879 Vesicle Vesicles SNAP25 P60880 P60879 Vesicle Vesicles _ Binding 10195194
ARRB1 P49407 Q8BWG8 Adapter Cytosol AP2S1 P53680 P62743 Adapter Vesicles 0 Binding 10770944
MAP3K1 Q13233 P53349 Kinase Cytosol NFKBIA P25963 Q9Z1E3 Inhibitor Cytosol _ Phosphorylation 9689078
DLG4 P78352 Q62108 Adapter Cytosol KCNA2 P16389 P63141 Channel Membrane 0 Binding 7477295
OPRD1 P41143 P32300 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 15082510
TRADD Q15628 NA Adapter Cytosol TRAF2 Q12933 P39429 Adapter Cytosol + Binding 8565075
TRADD Q15628 NA Adapter Cytosol TRAF2 Q12933 P39429 Adapter Cytosol + Binding 10911999
DLG4 P78352 Q62108 Adapter Cytosol CACNA1C Q13936 Q01815 Channel Membrane 0 Binding 12850569
SEROTONIN NA NA Ligand Extracellular HTR4 Q13639 P97288 Receptor Membrane + Binding 2314390
SEROTONIN NA NA Ligand Extracellular HTR4 Q13639 P97288 Receptor Membrane + Binding 7796807
PPP2R5C Q13362 Q60996 Phosphatase Cytosol BCL2 P10415 P10417 Bcl2Family Mitochondria _ Dephosphorylation 9852076
CAMK2A Q9UQM7 P11798 Kinase Cytosol ACTN3 Q08043 O88990 Cytoskeleton Cytosol 0 Binding 11160423
EGFR P00533 Q01279 Receptor Membrane SHC1 P29353 P98083 Adapter Cytosol + Binding 8808684
EGFR P00533 Q01279 Receptor Membrane SHC1 P29353 P98083 Adapter Cytosol + Binding 7681824
PTK2 Q05397 P34152 Kinase Cytosol BCAR1 P56945 Q61140 Adapter Cytosol 0 Binding 8662921
PPP1R9B Q96SB3 Q6R891 Cytoskeleton Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol 0 Binding 15228588
PPP1R9B Q96SB3 Q6R891 Cytoskeleton Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol 0 Binding 12417592
PPP1R9B Q96SB3 Q6R891 Cytoskeleton Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol 0 Binding 9452470
PRKCA P17252 P20444 Kinase Cytosol MBP P02686 P04370 Cytoskeleton Cytosol + Phosphorylation 10460230
AKT1 P31749 P31750 Kinase Cytosol FOXO1A Q12778 Q9R1E0 TF Nucleus _ Phosphorylation 10102273
AKT1 P31749 P31750 Kinase Cytosol FOXO1A Q12778 Q9R1E0 TF Nucleus _ Phosphorylation 10358075
AP1B1 Q10567 O35643 Adapter Cytosol SYP P08247 Q62277 Vesicle Vesicles 0 Binding 12498786
TP53BP1 Q12888 P70399 TF Nucleus CREBBP Q92793 P45481 TF Nucleus 0 Binding 9215639
LCK P06239 P06240 Kinase Cytosol VAV1 P15498 P27870 GEF Cytosol + Phosphorylation 12400014
DUSP4 Q13115 Q8BFV3 Phosphatase Cytosol MAPK8 P45983 Q91Y86 Kinase Nucleus _ Dephosphorylation 8626452
DUSP4 Q13115 Q8BFV3 Phosphatase Cytosol MAPK1 P28482 P63085 Kinase Cytosol _ Dephosphorylation 8626452
GABBR1 Q9UBS5 Q9WV18 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 11416164
THC NA NA Ligand Extracellular CNR1 P21554 P47746 Receptor Membrane + Binding 2165569
THC NA NA Ligand Extracellular CNR1 P21554 P47746 Receptor Membrane + Binding 2308954
ITGB1 P05556 P09055 CellAdhesion Membrane PTK2B Q14289 Q9QVP9 Kinase Cytosol + Binding 9022036
ITGB1 P05556 P09055 CellAdhesion Membrane PTK2B Q14289 Q9QVP9 Kinase Cytosol + Binding 9366396
JUNB P17275 P09450 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 1827203
JUNB P17275 P09450 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 12192032
PRKCA P17252 P20444 Kinase Cytosol DGUOK Q16854 Q9QX60 Kinase Cytosol _ Phosphorylation 12890670
PRKCA P17252 P20444 Kinase Cytosol DGUOK Q16854 Q9QX60 Kinase Cytosol _ Phosphorylation 9716136
GSK3A P49840 NA Kinase Cytosol NFATC1 O95644 O88942 TF Nucleus _ Phosphorylation 11063740
PDGFRB P09619 P05622 Receptor Membrane SLC9A3R1 O14745 P70441 Adapter Cytosol 0 Binding 11882663
OPRM1 P35372 P42866 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 15082510
EPB41 P11171 P48193 Adapter Cytosol GRIA1 P42261 P23818 Channel Membrane + Binding 11050113
GNB2 P62879 P62880 Gprotein Cytosol RASGRP3 Q8IV61 NA GAP Cytosol + Binding 8714559
GNB2L1 P63244 P68040 Adapter Cytosol PRKCA P17252 P20444 Kinase Cytosol 0 Binding 11956211
GNB2L1 P63244 P68040 Adapter Cytosol PRKCA P17252 P20444 Kinase Cytosol 0 Binding 1831196
GNB2L1 P63244 P68040 Adapter Cytosol PRKCA P17252 P20444 Kinase Cytosol 0 Binding 7831317
FOSB P53539 P13346 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 1827203
FOSB P53539 P13346 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 12192032
GNA13 Q14344 P27601 Gprotein Cytosol RDX P35241 P26043 Adapter Cytosol + Binding 10816569
ADCY1 Q08828 O88444 Cyclase Cytosol CAMP P49913 P51437 Messenger Cytosol + Synthesis 2022671
CALM3 P62158 P62204 Activator Cytosol DAPK1 P53355 Q80YE7 Kinase Cytosol + Binding 9367156
SEC61A1 P61619 P61620 Channel ER NASCENTCHAIN NA NA Peptide Ribosomes 0 Binding 12887911
CALCIUM NA NA Messenger Cytosol RPH3A Q9Y2J0 P47708 Vesicle Vesicles + Binding 8262955
PRKCA P17252 P20444 Kinase Cytosol GRIK1 P39086 Q60934 Channel Membrane + Phosphorylation 12597860
PLAA Q9Y263 P27612 Phospholipase Cytosol AA NA NA Lipid Cytosol + Synthesis 2119631
PLAA Q9Y263 P27612 Phospholipase Cytosol AA NA NA Lipid Cytosol + Synthesis 874074
DUSP2 Q05923 Q05922 Phosphatase Cytosol MAPK14 Q16539 P47811 Kinase Cytosol _ Dephosphorylation 8626452
CTNNA1 P35221 P26231 Cytoskeleton Cytosol CTNNB1 P35222 Q02248 TF Cytosol 0 Binding 12640114
FYN P06241 P39688 Kinase Cytosol SF1 Q15637 Q64213 Adapter Cytosol 0 Phosphorylation 14647465
CAMK2A Q9UQM7 P11798 Kinase Cytosol SYNGAP1 Q96PV0 NA GEF Cytosol _ Phosphorylation 9620694
CAMK2A Q9UQM7 P11798 Kinase Cytosol STX3 Q13277 Q64704 Vesicle Vesicles _ Binding 11978810
GRASP Q7Z6J2 Q9JJA9 Adapter Cytosol SYK P43405 P48025 Kinase Cytosol + Binding 15173175
HOMER2 Q9NSB8 Q9QWW1 Adapter Cytosol RYR1 P21817 NA Channel ER + Binding 12223488
PICK1 Q9NRD5 Q62083 Adapter Cytosol GRM7 Q14831 Q68ED2 Receptor Membrane _ Binding 10488094
EGFR P00533 Q01279 Receptor Membrane GRB2 P62993 Q60631 Adapter Cytosol + Binding 1322798
CALM3 P62158 P62204 Activator Cytosol RIT2 Q99578 P70425 GTPase Cytosol + Binding 8824319
CALM3 P62158 P62204 Activator Cytosol RIT2 Q99578 P70425 GTPase Cytosol + Binding 9813038
CALM3 P62158 P62204 Activator Cytosol RIT2 Q99578 P70425 GTPase Cytosol + Binding 14662747
STXBP6 Q8NFX7 Q8R3T5 Vesicle Vesicles STX3 Q13277 Q64704 Vesicle Vesicles _ Binding 12145319
COL1A1 P02452 P11087 Matrix Extracellular ITGB1 P05556 P09055 CellAdhesion Membrane + Binding 7716514
NLGN1 Q8N2Q7 Q99K10 CellAdhesion Membrane CNTNAP1 P78357 O54991 CellAdhesion Membrane 0 Binding 7736595
NLGN1 Q8N2Q7 Q99K10 CellAdhesion Membrane CNTNAP1 P78357 O54991 CellAdhesion Membrane 0 Binding 9325340
ADRB2 P07550 P18762 Receptor Membrane GNAS P63092 P63094 Gprotein Cytosol + Binding 6149763
ADRB2 P07550 P18762 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 6149763
RIMS1 Q86UR5 Q99NE5 Adapter Vesicles UNC13B O14795 Q9Z1N9 Vesicle Vesicles + Binding 11343654
MAPK1 P28482 P63085 Kinase Cytosol MEF2B Q02080 O55087 TF Nucleus + Phosphorylation 9069290
MAPK1 P28482 P63085 Kinase Cytosol MEF2B Q02080 O55087 TF Nucleus + Phosphorylation 9384584
RAC1 P63000 P63001 GTPase Cytosol DMPK Q09013 P54265 Kinase Cytosol + Binding 10869570
PXN P49023 Q8VI36 Adapter Cytosol PAK1 Q13153 O88643 Kinase Cytosol 0 Binding 11096073
HTR1A P08908 Q64264 Receptor Membrane GNAZ P19086 O70443 Gprotein Cytosol + Binding 9407078
S6 NA NA Adapter Ribosomes S40 NA NA Ribosome Ribosomes + Binding 947902
PRKACA P17612 P05132 Kinase Cytosol KCNJ4 P48050 P52189 Channel Membrane _ Phosphorylation 8893032
HTR1A P08908 Q64264 Receptor Membrane GNAS P63092 P63094 Gprotein Cytosol + Binding 2941565
HTR1A P08908 Q64264 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 2941565
EIF4G2 P78344 Q62448 Ribosome Ribosomes mRNA NA NA RNA Ribosomes 0 Binding 3804998
AA NA NA Lipid Cytosol PRKCA P17252 P20444 Kinase Cytosol + Binding 2119631
AA NA NA Lipid Cytosol PRKCA P17252 P20444 Kinase Cytosol + Binding 3934001
BID P55957 P70444 Bcl2Family Cytosol COX5B P10606 P19536 Activator Mitochondria + Binding 9727492
PRKACA P17612 P05132 Kinase Cytosol GRIK1 P39086 Q60934 Channel Membrane + Phosphorylation 8094892
VASP P50552 P70460 Adapter Cytosol CAPZB P47756 P47757 Cytoskeleton Cytosol 0 Binding 9034331
MYLK Q15746 Q6PDN3 Kinase Cytosol MYO18A Q92614 Q9JMH9 Cytoskeleton Cytosol + Phosphorylation 6893940
MYLK Q15746 Q6PDN3 Kinase Cytosol MYO18A Q92614 Q9JMH9 Cytoskeleton Cytosol + Phosphorylation 4522294
MYLK Q15746 Q6PDN3 Kinase Cytosol MYO18A Q92614 Q9JMH9 Cytoskeleton Cytosol + Phosphorylation 6934518
FN1 P02751 P11276 Matrix Extracellular ITGB1 P05556 P09055 CellAdhesion Membrane + Binding 6284125
SRC P12931 P05480 Kinase Cytosol CACNA1C Q13936 Q01815 Channel Membrane + Phosphorylation 12850569
CHRNA7 P36544 P49582 Receptor Membrane SODIUM NA NA Ion Cytosol + Opening 977572
CHRNA7 P36544 P49582 Receptor Membrane SODIUM NA NA Ion Cytosol + Opening 3753746
STX3 Q13277 Q64704 Vesicle Vesicles KCNA1 Q09470 P16388 Channel Membrane + Binding 12114518
DIABLO Q9NR28 Q9JIQ3 Inhibitor Mitochondria BIRC4 P98170 Q60989 Inhibitor Cytosol _ Binding 10929712
BRRN1 Q15003 Q8C156 Adapter Cytosol CTNND2 Q9UQB3 O35927 Adapter Cytosol 0 Binding 11729199
PIP2 NA NA Lipid Cytosol WASF1 Q92558 Q8R5H6 Activator Cytosol + Binding 10444357
PIP2 NA NA Lipid Cytosol WASF1 Q92558 Q8R5H6 Activator Cytosol + Binding 8895577
PIP2 NA NA Lipid Cytosol WASF1 Q92558 Q8R5H6 Activator Cytosol + Binding 11052943
CALM3 P62158 P62204 Activator Cytosol RIN1 Q13671 Q921Q7 Activator Cytosol + Binding 8824319
PIK3CA P42336 P42337 Kinase Cytosol PIP3 NA NA Lipid Membrane + Phosphorylation 2833705
PIK3CA P42336 P42337 Kinase Cytosol PIP2 NA NA Lipid Membrane _ Phosphorylation 2833705
PRKCA P17252 P20444 Kinase Cytosol GRIA1 P42261 P23818 Channel Membrane _ Phosphorylation 12805550
ARFGAP1 Q8N6T3 Q9EPJ9 GAP Vesicles ARF1 P84077 P84078 GTPase Vesicles _ GAP 1010276
PSCD2 Q99418 P63034 GEF Cytosol ARF1 P84077 P84078 GTPase Vesicles + GEF 8945478
OPRL1 P41146 P35377 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 15082510
BRADYKININ NA NA Ligand Extracellular BDKRB1 P46663 Q61125 Receptor Membrane + Binding 6113593
BRADYKININ NA NA Ligand Extracellular BDKRB1 P46663 Q61125 Receptor Membrane + Binding 2907120
BRADYKININ NA NA Ligand Extracellular BDKRB1 P46663 Q61125 Receptor Membrane + Binding 1652448
PTK2 Q05397 P34152 Kinase Cytosol SHC1 P29353 P98083 Adapter Cytosol + Phosphorylation 10725339
RANBP9 Q96S59 P69566 Adapter Cytosol CALB1 P05937 P12658 Adapter Cytosol 0 Binding 12684061
CAPN1 P07384 O35350 Protease Cytosol SPTBN2 O15020 NA Cytoskeleton Cytosol _ Cleavage 11880203
CAPN1 P07384 O35350 Protease Cytosol SPTBN2 O15020 NA Cytoskeleton Cytosol _ Cleavage 12446661
PRKCA P17252 P20444 Kinase Cytosol ADD1 P35611 Q9QYC0 Adapter Cytosol _ Phosphorylation 9679146
PRKCA P17252 P20444 Kinase Cytosol ADD1 P35611 Q9QYC0 Adapter Cytosol _ Phosphorylation 8810272
CAMK2A Q9UQM7 P11798 Kinase Cytosol PPP2R5C Q13362 Q60996 Phosphatase Cytosol _ Dephosphorylation 10646534
DLG4 P78352 Q62108 Adapter Cytosol FYN P06241 P39688 Kinase Cytosol 0 Binding 9892651
PRKACA P17612 P05132 Kinase Cytosol KCND2 Q9NZV8 Q9Z0V2 Channel Membrane _ Phosphorylation 12451113
RAF1 P04049 Q99N57 Kinase Cytosol MAP4K1 Q92918 P70218 Kinase Cytosol + Phosphorylation 7624324
CASP3 P42574 P70677 Protease Cytosol PTEN P60484 O08586 Phosphatase Cytosol _ Cleavage 12788938
CAMK4 Q16566 P08414 Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 8195196
CAMK4 Q16566 P08414 Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 11970865
CAMK4 Q16566 P08414 Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 7958915
L1CAM P32004 P11627 CellAdhesion Membrane AP2S1 P53680 P62743 Adapter Vesicles 0 Binding 12070130
SHC1 P29353 P98083 Adapter Cytosol CHN1 P15882 Q91V57 GAP Cytosol 0 Binding 12446789
KCNIP3 Q9Y2W7 P0C092 TF Nucleus DRE NA NA DNA Nucleus _ Binding 10078534
KCNIP3 Q9Y2W7 P0C092 TF Nucleus DRE NA NA DNA Nucleus _ Binding 11108959
HSPA5 P11021 P20029 Chaperone ER NASCENTCHAIN NA NA Peptide Ribosomes 0 Binding 3084497
ADENOSINE NA NA Ligand Extracellular ADORA1 P30542 Q60612 Receptor Membrane + Binding 6162091
ADENOSINE NA NA Ligand Extracellular ADORA1 P30542 Q60612 Receptor Membrane + Binding 1646713
ADENOSINE NA NA Ligand Extracellular ADORA1 P30542 Q60612 Receptor Membrane + Binding 1857334
RIMS1 Q86UR5 Q99NE5 Adapter Vesicles YWHAH Q04917 P68510 Adapter Cytosol + Binding 12871946
SPTBN2 O15020 NA Cytoskeleton Cytosol PTPRN Q16849 Q60673 Receptor Membrane 0 Binding 11086001
NCK1 P16333 NA Adapter Cytosol PAK1 Q13153 O88643 Kinase Cytosol + Binding 9024622
NCK1 P16333 NA Adapter Cytosol PAK1 Q13153 O88643 Kinase Cytosol + Binding 11096073
NCK1 P16333 NA Adapter Cytosol PAK1 Q13153 O88643 Kinase Cytosol + Binding 8824201
NCK1 P16333 NA Adapter Cytosol PAK1 Q13153 O88643 Kinase Cytosol + Binding 9755165
FOSL1 P15407 P48755 TF Nucleus JUND P17535 P15066 TF Nucleus 0 Binding 1827203
FOSL1 P15407 P48755 TF Nucleus JUND P17535 P15066 TF Nucleus 0 Binding 12192032
FOSL1 P15407 P48755 TF Nucleus JUNB P17275 P09450 TF Nucleus 0 Binding 1827203
FOSL1 P15407 P48755 TF Nucleus JUNB P17275 P09450 TF Nucleus 0 Binding 12192032
CASP8 Q14790 O89110 Protease Cytosol PROKR1 Q8TCW9 Q9JKL1 Kinase Cytosol _ Cleavage 11555640
L1CAM P32004 P11627 CellAdhesion Membrane RANBP9 Q96S59 P69566 RAN P62826 + Binding 16000162
TNIK Q9UKE5 P83510 Kinase Cytosol TRAF2 Q12933 P39429 Adapter Cytosol 0 Binding 10521462
PIP2 NA NA Lipid Cytosol GSN P06396 P13020 Cytoskeleton Cytosol + Binding 10660524
PIP2 NA NA Lipid Cytosol GSN P06396 P13020 Cytoskeleton Cytosol + Binding 11042212
PPP2R5C Q13362 Q60996 Phosphatase Cytosol CFL1 P23528 P18760 Cytoskeleton Cytosol + Dephosphorylation 11093160
OPRL1 P41146 P35377 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 15082510
MAPK8 P45983 Q91Y86 Kinase Nucleus JUN P05412 P05627 TF Nucleus + Phosphorylation 9407028
MAPK8 P45983 Q91Y86 Kinase Nucleus JUN P05412 P05627 TF Nucleus + Phosphorylation 12853483
MAPK8 P45983 Q91Y86 Kinase Nucleus JUN P05412 P05627 TF Nucleus + Phosphorylation 7935387
MAPK8 P45983 Q91Y86 Kinase Nucleus JUN P05412 P05627 TF Nucleus + Phosphorylation 8137421
MAPK8 P45983 Q91Y86 Kinase Nucleus JUN P05412 P05627 TF Nucleus + Phosphorylation 1608942
AKAP5 P24588 NA Adapter Cytosol CACNA1C Q13936 Q01815 Channel Membrane 0 Binding 9620705
CASP3 P42574 P70677 Protease Cytosol MEF2B Q02080 O55087 TF Nucleus _ Cleavage 11904443
SYT1 P21579 P46096 Vesicle Vesicles CACNA1E Q15878 Q61290 Channel Membrane + Binding 12645522
SYT1 P21579 P46096 Vesicle Vesicles CACNA1C Q13936 Q01815 Channel Membrane + Binding 12645522
SYT1 P21579 P46096 Vesicle Vesicles CACNA1A O00555 P97445 Channel Membrane 0 Binding 9593683
PRKACA P17612 P05132 Kinase Cytosol GRIA1 P42261 P23818 Channel Membrane + Phosphorylation 12843287
PSEN1 P49768 P49769 Protease Membrane MAPT P10636 P10637 Activator Cytosol 0 Binding 9689133
DUSP2 Q05923 Q05922 Phosphatase Cytosol MAPK1 P28482 P63085 Kinase Cytosol _ Dephosphorylation 8626452
CHRM4 P08173 P32211 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 7916637
CHRM4 P08173 P32211 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 10347206
CHOLESTEROL NA NA Lipid Membrane SYP P08247 Q62277 Vesicle Vesicles + Binding 12485399
DPYSL2 Q16555 O08553 Activator Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol + Binding 12134159
CAMK2A Q9UQM7 P11798 Kinase Cytosol MPDZ O75970 Q8VBX6 Adapter Cytosol 0 Binding 15312654
FOS P01100 P01101 TF Nucleus JUND P17535 P15066 TF Nucleus 0 Binding 1827203
FOS P01100 P01101 TF Nucleus JUND P17535 P15066 TF Nucleus 0 Binding 12192032
FOS P01100 P01101 TF Nucleus JUNB P17275 P09450 TF Nucleus 0 Binding 1827203
FOS P01100 P01101 TF Nucleus JUNB P17275 P09450 TF Nucleus 0 Binding 12192032
DLGAP1 O14490 Q9D415 Adapter Cytosol SHANK1 Q9Y566 NA Adapter Cytosol 0 Binding 10433268
PENK P01210 P22005 Ligand Extracellular OPRM1 P35372 P42866 Receptor Membrane + Binding 15082510
GRM1 Q13255 P97772 Receptor Membrane GRASP Q7Z6J2 Q9JJA9 Adapter Cytosol + Binding 11850456
GRM1 Q13255 P97772 Receptor Membrane GRASP Q7Z6J2 Q9JJA9 Adapter Cytosol + Binding 15173175
KCNA1 Q09470 P16388 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 2451788
PENK P01210 P22005 Ligand Extracellular OPRL1 P41146 P35377 Receptor Membrane + Binding 15082510
DUSP1 P28562 P28563 Phosphatase Cytosol MAPK14 Q16539 P47811 Kinase Cytosol _ Dephosphorylation 8626452
SHANK1 Q9Y566 NA Adapter Cytosol ARHGEF7 Q14155 Q9ES28 GEF Cytosol + Binding 12626503
PAK1 Q13153 O88643 Kinase Cytosol MYLK Q15746 Q6PDN3 Kinase Cytosol _ Phosphorylation 10092231
EGFR P00533 Q01279 Receptor Membrane CRK P46108 Q64010 Adapter Cytosol 0 Binding 8662907
ITSN2 Q9NZM3 Q9Z0R6 Adapter Vesicles EPS15 P42566 P42567 Adapter Cytosol 0 Binding 10922467
PENK P01210 P22005 Ligand Extracellular OPRK1 P41145 P33534 Receptor Membrane + Binding 15082510
PRKCA P17252 P20444 Kinase Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol _ Phosphorylation 7694293
CAMK2A Q9UQM7 P11798 Kinase Cytosol RYR1 P21817 NA Channel ER + Phosphorylation 1645727
WASF1 Q92558 Q8R5H6 Activator Cytosol ARPC1B O15143 Q9WV32 Cytoskeleton Cytosol + Binding 10781580
GCC1 Q96CN9 Q9D4H2 Adapter Cytosol DNM1 Q05193 P39053 GTPase Vesicles 0 Binding 11309416
PPP3R1 P63098 Q63810 Phosphatase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria + Dephosphorylation 10195903
CAPZB P47756 P47757 Cytoskeleton Cytosol SYN1 P17600 O88935 Vesicle Vesicles 0 Binding 9463375
SERPINB2 P05120 P12388 Inhibitor Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol _ Binding 6327437
SERPINB2 P05120 P12388 Inhibitor Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol _ Binding 11812771
SERPINB2 P05120 P12388 Inhibitor Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol _ Binding 11320080
ZAP70 P43403 P43404 Kinase Cytosol VAV1 P15498 P27870 GEF Cytosol + Binding 7798261
GRM7 Q14831 Q68ED2 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 10488094
GRM7 Q14831 Q68ED2 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 11395497
GABRA1 P14867 P62812 Receptor Membrane CHLORIDE NA NA Ion Cytosol + Opening 2848320
CREM Q03060 P27699 TF Nucleus KCNIP3 Q9Y2W7 P0C092 TF Nucleus _ Binding 11094064
CREM Q03060 P27699 TF Nucleus KCNIP3 Q9Y2W7 P0C092 TF Nucleus _ Binding 12198160
CHRM1 P11229 P12657 Receptor Membrane RGS2 P41220 O08849 Gprotein Cytosol 0 Binding 14976183
BRRN1 Q15003 Q8C156 Adapter Cytosol GRIN2A Q12879 P35436 Receptor Membrane 0 Binding 10827168
SDC1 P18827 P18828 Receptor Membrane SDCBP O00560 O08992 Adapter Cytosol 0 Binding 9391086
SDC1 P18827 P18828 Receptor Membrane SDCBP O00560 O08992 Adapter Cytosol 0 Binding 11179419
SDC1 P18827 P18828 Receptor Membrane SDCBP O00560 O08992 Adapter Cytosol 0 Binding 10770943
GSN P06396 P13020 Cytoskeleton Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol _ Cleavage 9334393
MAPK14 Q16539 P47811 Kinase Cytosol ELK1 P19419 P41969 TF Nucleus + Phosphorylation 8622669
NGFB P01138 P01139 Ligand Extracellular NTRK1 P04629 NA Receptor Membrane + Binding 9547236
NGFB P01138 P01139 Ligand Extracellular NTRK1 P04629 NA Receptor Membrane + Binding 9290260
NGFB P01138 P01139 Ligand Extracellular NTRK1 P04629 NA Receptor Membrane + Binding 1706478
IGF1 P01343 P05017 Ligand Extracellular IGF1R P08069 Q60751 Receptor Cytosol + Binding 8408032
PDGFRB P09619 P05622 Receptor Membrane PTPN11 Q06124 P35235 Phosphatase Cytosol + Binding 8226787
PDGFRB P09619 P05622 Receptor Membrane PTPN11 Q06124 P35235 Phosphatase Cytosol + Binding 7688466
PPP2R5C Q13362 Q60996 Phosphatase Cytosol RCS NA NA Inhibitor Cytosol _ Dephosphorylation 15499021
SDCBP O00560 O08992 Adapter Cytosol NF2 P35240 P46662 Adapter Cytosol 0 Binding 11891216
CREB1 P16220 Q01147 TF Nucleus CRE NA NA DNA Nucleus + Binding 2885756
PDE1C Q14123 Q64338 PDE Cytosol cGMP NA NA Messenger Cytosol _ PDE 15082510
MKLN1 Q9UL63 O89050 Adapter Cytosol RANBP9 Q96S59 P69566 Adapter Cytosol 0 Binding 12559565
ARHGEF12 Q9NZN5 Q8R4H2 GEF Cytosol IGF1R P08069 Q60751 Receptor Cytosol 0 Binding 11724822
PENK P01210 P22005 Ligand Extracellular OPRD1 P41143 P32300 Receptor Membrane + Binding 15082510
PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol IP3 NA NA Lipid Cytosol + Cleavage 6325926
PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol IP3 NA NA Lipid Cytosol + Cleavage 6095092
PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol IP3 NA NA Lipid Cytosol + Cleavage 7076678
PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol IP3 NA NA Lipid Cytosol + Cleavage 7142213
SYNGAP1 Q96PV0 NA GEF Cytosol NRAS P01111 P08556 GTPase Cytosol _ GAP 9581761
SYNGAP1 Q96PV0 NA GEF Cytosol NRAS P01111 P08556 GTPase Cytosol _ GAP 15312654
RASGRP3 Q8IV61 NA GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 10934204
RASGRP3 Q8IV61 NA GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 9582122
RASGRP3 Q8IV61 NA GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 2833817
DLG4 P78352 Q62108 Adapter Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol 0 Binding 11031113
DLG4 P78352 Q62108 Adapter Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol 0 Binding 8922396
GNA13 Q14344 P27601 Gprotein Cytosol PTK2B Q14289 Q9QVP9 Kinase Cytosol + Binding 10821841
CERAMIDE NA NA Lipid Cytosol PRKCA P17252 P20444 Kinase Cytosol + Binding 9772184
CERAMIDE NA NA Lipid Cytosol PRKCA P17252 P20444 Kinase Cytosol + Binding 15189345
CACNA1C Q13936 Q01815 Channel Membrane SRI P30626 Q6P069 Adapter Cytosol 0 Binding 9668070
MAPK14 Q16539 P47811 Kinase Cytosol MAPKAPK2 P49137 P49138 Kinase Cytosol + Phosphorylation 7923353
MAPK14 Q16539 P47811 Kinase Cytosol MAPKAPK2 P49137 P49138 Kinase Cytosol + Phosphorylation 7592979
TNFRSF1A P19438 P25118 Receptor Membrane TRADD Q15628 NA Adapter Cytosol + Binding 7758105
NRAS P01111 P08556 GTPase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Binding 7811320
NRAS P01111 P08556 GTPase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Binding 8636091
NRAS P01111 P08556 GTPase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Binding 9867809
NRAS P01111 P08556 GTPase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Binding 9001246
NRAS P01111 P08556 GTPase Cytosol RALGDS Q12967 Q03385 GEF Cytosol + Binding 7809086
CHN1 P15882 Q91V57 GAP Cytosol CDC42 P60953 P60766 GTPase Cytosol _ GAP 12446789
AXIN1 O15169 O35625 Adapter Cytosol GSK3A P49840 NA Kinase Cytosol + Binding 10196136
AXIN1 O15169 O35625 Adapter Cytosol GSK3A P49840 NA Kinase Cytosol + Binding 9482734
AXIN1 O15169 O35625 Adapter Cytosol GSK3A P49840 NA Kinase Cytosol + Binding 9501208
AXIN1 O15169 O35625 Adapter Cytosol GSK3A P49840 NA Kinase Cytosol + Binding 9601641
AXIN1 O15169 O35625 Adapter Cytosol GSK3A P49840 NA Kinase Cytosol + Binding 11707456
DAG NA NA Lipid Cytosol RASGRP3 Q8IV61 NA GAP Cytosol + Binding 9582122
GRB10 Q13322 Q60760 Adapter Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 12783867
ERBB2 P04626 P70424 Receptor Membrane ERBB2IP Q96RT1 Q80TH2 Adapter Cytosol 0 Binding 11279080
CALCIUM NA NA Messenger Cytosol VSNL1 P62760 P62761 Adapter Cytosol + Binding 1359372
CALCIUM NA NA Messenger Cytosol VSNL1 P62760 P62761 Adapter Cytosol + Binding 7806504
TNIK Q9UKE5 P83510 Kinase Cytosol NCK1 P16333 NA Adapter Cytosol 0 Binding 10521462
CAMK4 Q16566 P08414 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles + Phosphorylation 10400638
NTRK1 P04629 NA Receptor Membrane PLCG1 P19174 Q62077 Phospholipase Cytosol + Binding 8552402
SYK P43405 P48025 Kinase Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol + Phosphorylation 8617742
FYN P06241 P39688 Kinase Cytosol CTNNB1 P35222 Q02248 TF Cytosol + Phosphorylation 12640114
ADORA1 P30542 Q60612 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 6162091
CASP7 P55210 P97864 Protease Cytosol PROKR1 Q8TCW9 Q9JKL1 Kinase Cytosol _ Cleavage 11555640
PIP3 NA NA Lipid Membrane SH3KBP1 Q96B97 Q8R550 Phosphatase Cytosol + Binding 10508402
ERBB2 P04626 P70424 Receptor Membrane PIK3CA P42336 P42337 Kinase Cytosol + Binding 8026468
EEF2K O00418 O08796 GTPase Ribosomes EEF2 P13639 P58252 GTPase Ribosomes _ Phosphorylation 3693353
EEF2K O00418 O08796 GTPase Ribosomes EEF2 P13639 P58252 GTPase Ribosomes _ Phosphorylation 9133370
EEF2K O00418 O08796 GTPase Ribosomes EEF2 P13639 P58252 GTPase Ribosomes _ Phosphorylation 3906654
EEF2K O00418 O08796 GTPase Ribosomes EEF2 P13639 P58252 GTPase Ribosomes _ Phosphorylation 2704236
EEF2K O00418 O08796 GTPase Ribosomes EEF2 P13639 P58252 GTPase Ribosomes _ Phosphorylation 2458772
SYNTABULIN NA NA Adapter Cytosol KNS2 Q07866 O88447 Cytoskeleton Cytosol 0 Binding 15459722
PDE5A O76074 Q8CG03 PDE Cytosol cGMP NA NA Messenger Cytosol _ PDE 15082510
CREBBP Q92793 P45481 TF Nucleus ELK1 P19419 P41969 TF Nucleus + Binding 8941362
RHEB Q15382 Q921J2 GTPase Cytosol FRAP1 P42345 Q9JLN9 Kinase Cytosol + Binding 12820960
RHEB Q15382 Q921J2 GTPase Cytosol FRAP1 P42345 Q9JLN9 Kinase Cytosol + Binding 12842888
PRKG2 Q13237 Q61410 Kinase Cytosol PDE5A O76074 Q8CG03 PDE Cytosol + Phosphorylation 15082510
FKBP1A P62942 P26883 Adapter Cytosol ITPR1 Q14643 P11881 Channel ER 0 Binding 8521476
CAMP P49913 P51437 Messenger Cytosol PRKACA P17612 P05132 Kinase Cytosol + Binding 2423884
CHRM2 P08172 Q9ERZ4 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 2850835
CHRM2 P08172 Q9ERZ4 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 2823384
DMPK Q09013 P54265 Kinase Cytosol SRF P11831 NA TF Nucleus + Phosphorylation 12809504
NTRK2 Q16620 P15209 Receptor Membrane SHC1 P29353 P98083 Adapter Cytosol + Binding 8808684
EIF4G2 P78344 Q62448 Ribosome Ribosomes ACE P22966 P22967 Ribosome Ribosomes 0 Binding 10944120
PDE4C Q08493 Q3UEI1 PDE Cytosol CAMP P49913 P51437 Messenger Cytosol _ PDE 9429761
SV2A Q7L0J3 Q9JIS5 Vesicle Vesicles SYT1 P21579 P46096 Vesicle Vesicles + Binding 8910372
SHC1 P29353 P98083 Adapter Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 7537361
CFLAR O15519 O35732 Inhibitor Cytosol CASP8 Q14790 O89110 Protease Cytosol _ Binding 9217161
PRKACA P17612 P05132 Kinase Cytosol GDNF P39905 P48540 TF Nucleus + Phosphorylation 1655749
SEC63 Q9UGP8 Q8VHE0 Adapter ER SEC61A1 P61619 P61620 Channel ER + Binding 10799540
CHRM4 P08173 P32211 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 7916637
SRC P12931 P05480 Kinase Cytosol PLCG1 P19174 Q62077 Phospholipase Cytosol + Phosphorylation 8388373
SRC P12931 P05480 Kinase Cytosol PLCG1 P19174 Q62077 Phospholipase Cytosol + Phosphorylation 7682059
CASP8 Q14790 O89110 Protease Cytosol BID P55957 P70444 Bcl2Family Cytosol + Cleavage 9727492
CASP8 Q14790 O89110 Protease Cytosol BID P55957 P70444 Bcl2Family Cytosol + Cleavage 9873064
ARRB1 P49407 Q8BWG8 Adapter Cytosol FZD1 Q9UP38 O70421 Receptor Membrane + Binding 11742073
PIP2 NA NA Messenger Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 9452513
PIP2 NA NA Messenger Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 9325335
PIP2 NA NA Messenger Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 8947047
PLCG1 P19174 Q62077 Phospholipase Cytosol IP3 NA NA Lipid Cytosol + Synthesis 2831461
PLCG1 P19174 Q62077 Phospholipase Cytosol IP3 NA NA Lipid Cytosol + Synthesis 3541924
PLCG1 P19174 Q62077 Phospholipase Cytosol IP3 NA NA Lipid Cytosol + Synthesis 3040753
PLCG1 P19174 Q62077 Phospholipase Cytosol IP3 NA NA Lipid Cytosol + Synthesis 2840660
CAPZB P47756 P47757 Cytoskeleton Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol + Binding 9463375
CAPZB P47756 P47757 Cytoskeleton Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol + Binding 6893804
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol MAPT P10636 P10637 Activator Cytosol + Phosphorylation 6412713
SYT1 P21579 P46096 Vesicle Vesicles STX3 Q13277 Q64704 Vesicle Vesicles + Binding 1321498
SYT1 P21579 P46096 Vesicle Vesicles STX3 Q13277 Q64704 Vesicle Vesicles + Binding 7559535
INADL Q8NI35 Q63ZW7 Adapter Cytosol GRIN2A Q12879 P35436 Receptor Membrane 0 Binding 9647694
CRK P46108 Q64010 Adapter Cytosol RAPGEF1 Q13905 NA GEF Cytosol + Binding 9560161
CRK P46108 Q64010 Adapter Cytosol RAPGEF1 Q13905 NA GEF Cytosol + Binding 9591773
PRKCA P17252 P20444 Kinase Cytosol DNM1 Q05193 P39053 GTPase Vesicles _ Phosphorylation 8063723
NTRK1 P04629 NA Receptor Membrane CRK P46108 Q64010 Adapter Cytosol + Binding 12446789
NTRK1 P04629 NA Receptor Membrane CRK P46108 Q64010 Adapter Cytosol + Binding 8552402
PTEN P60484 O08586 Phosphatase Cytosol PTK2 Q05397 P34152 Kinase Cytosol _ Dephosphorylation 9616126
GRIN2A Q12879 P35436 Receptor Membrane MALS NA NA Adapter Cytosol 0 Binding 10341223
CHRM2 P08172 Q9ERZ4 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 8786435
CHRM2 P08172 Q9ERZ4 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 3919024
CHRM2 P08172 Q9ERZ4 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 3929139
DYRK1A Q13627 Q61214 Kinase Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Phosphorylation 11877424
OPRL1 P41146 P35377 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 15082510
WASF1 Q92558 Q8R5H6 Activator Cytosol MAP3K14 Q99558 Q9WUL6 Kinase Cytosol 0 Binding 7565724
ANP32A P39687 O35381 Activator Cytosol APAF1 O14727 O88879 Adapter Cytosol + Binding 12522243
ARHGAP1 Q07960 NA GTPase Cytosol ROCK2 O75116 P70336 Kinase Cytosol + Binding 8772201
GRIK1 P39086 Q60934 Channel Membrane CDH2 P19022 P15116 CellAdhesion Membrane 0 Binding 12151522
RASGRF1 Q13972 P27671 GEF Cytosol RAC1 P63000 P63001 GTPase Cytosol + GEF 10220378
RASGRF1 Q13972 P27671 GEF Cytosol RAC1 P63000 P63001 GTPase Cytosol + GEF 10544264
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol EGFR P00533 Q01279 Receptor Membrane _ Ubiquitination 11375397
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol PPP1R14A Q96A00 Q91VC7 Inhibitor Cytosol 0 Binding 15003508
MAP2K1IP1 Q9UHA4 O88653 Adapter Cytosol MAPK1 P28482 P63085 Kinase Cytosol + Binding 9733512
GCC1 Q96CN9 Q9D4H2 Adapter Cytosol PCLO Q9Y6V0 Q9QYX7 Adapter Cytosol 0 Binding 12654920
BAX Q07812 Q07813 Bcl2Family Mitochondria COX5B P10606 P19536 Activator Mitochondria + Binding 11139284
CNKSR1 Q969H4 NA Kinase Cytosol MAPK1 P28482 P63085 Kinase Cytosol 0 Binding 10891492
IRS2 Q9Y4H2 P81122 Adapter Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 9374521
PRKCA P17252 P20444 Kinase Cytosol ADRBK1 P25098 Q99MK8 Kinase Cytosol _ Phosphorylation 9013639
SSTR1 P30872 P30873 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 8145728
CDC42 P60953 P60766 GTPase Cytosol PAK1 Q13153 O88643 Kinase Cytosol + Binding 7499279
CDC42 P60953 P60766 GTPase Cytosol PAK1 Q13153 O88643 Kinase Cytosol + Binding 810774
NT4 NA NA Ligand Extracellular NTRK2 Q16620 P15209 Receptor Membrane + Binding 9354329
NT4 NA NA Ligand Extracellular NTRK2 Q16620 P15209 Receptor Membrane + Binding 8264643
NT4 NA NA Ligand Extracellular NTRK2 Q16620 P15209 Receptor Membrane + Binding 9728914
AP2S1 P53680 P62743 Adapter Vesicles CLTA P09496 O08585 Vesicle Vesicles 0 Binding 2912448
AP2S1 P53680 P62743 Adapter Vesicles CLTA P09496 O08585 Vesicle Vesicles 0 Binding 1902233
AP2S1 P53680 P62743 Adapter Vesicles CLTA P09496 O08585 Vesicle Vesicles 0 Binding 7559550
SF1 Q15637 Q64213 Adapter Cytosol mRNA NA NA RNA Ribosomes 0 Binding 7512694
IGF1R P08069 Q60751 Receptor Cytosol IRS1 P35568 P35569 Adapter Cytosol + Binding 8776723
CAMK4 Q16566 P08414 Kinase Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol _ Phosphorylation 10400690
SUMO3 P55854 Q9Z172 Sumo Cytosol FOS P01100 P01101 TF Nucleus _ Sumolation 16055710
DSCR1 P53805 Q9JHG6 Inhibitor Cytosol PPP3R1 P63098 Q63810 Phosphatase Cytosol _ Binding 12039863
DSCR1 P53805 Q9JHG6 Inhibitor Cytosol PPP3R1 P63098 Q63810 Phosphatase Cytosol _ Binding 10899116
PRKACA P17612 P05132 Kinase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria _ Phosphorylation 10851172
PRKACA P17612 P05132 Kinase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria _ Phosphorylation 10880354
PRKACA P17612 P05132 Kinase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria _ Phosphorylation 10230394
ROCK2 O75116 P70336 Kinase Cytosol MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol + Phosphorylation 16195223
GPHN Q9NQX3 NA Adapter Membrane TUBA3 Q71U36 NA Cytoskeleton Cytosol 0 Binding 1319186
GRIN2A Q12879 P35436 Receptor Membrane ACTN3 Q08043 O88990 Cytoskeleton Cytosol 0 Binding 12379661
GRIN2A Q12879 P35436 Receptor Membrane ACTN3 Q08043 O88990 Cytoskeleton Cytosol 0 Binding 9009191
GRIN2A Q12879 P35436 Receptor Membrane ACTN3 Q08043 O88990 Cytoskeleton Cytosol 0 Binding 11246149
GRIN2A Q12879 P35436 Receptor Membrane ACTN3 Q08043 O88990 Cytoskeleton Cytosol 0 Binding 9952395
GRIN2A Q12879 P35436 Receptor Membrane ACTN3 Q08043 O88990 Cytoskeleton Cytosol 0 Binding 9728925
LRP16 Q9BQ69 Q922B1 Receptor Membrane FZD1 Q9UP38 O70421 Receptor Membrane + Binding 12857724
RPS6KB1 P23443 Q8BSK8 Kinase Cytosol CREM Q03060 P27699 TF Nucleus + Phosphorylation 7923380
CHUK O15111 Q60680 Kinase Cytosol NFKBIA P25963 Q9Z1E3 Inhibitor Cytosol 0 Binding 9346241
CHUK O15111 Q60680 Kinase Cytosol NFKBIA P25963 Q9Z1E3 Inhibitor Cytosol 0 Binding 9252186
FYN P06241 P39688 Kinase Cytosol GRIN2A Q12879 P35436 Receptor Membrane + Phosphorylation 11677266
FYN P06241 P39688 Kinase Cytosol GRIN2A Q12879 P35436 Receptor Membrane + Phosphorylation 9670010
FYN P06241 P39688 Kinase Cytosol GRIN2A Q12879 P35436 Receptor Membrane + Phosphorylation 9892651
EIF4G2 P78344 Q62448 Ribosome Ribosomes CARD14 Q9BXL6 Q99KF0 Kinase Cytosol 0 Binding 9878069
RPS6KA5 O75582 Q8C050 Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 9687510
PPP2R5C Q13362 Q60996 Phosphatase Cytosol BCAR1 P56945 Q61140 Adapter Cytosol _ Dephosphorylation 11593413
PIP3 NA NA Lipid Membrane PDPK1 O15530 Q9Z2A0 Kinase Cytosol + Binding 9094314
DLGAP1 O14490 Q9D415 Adapter Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol + Binding 11122378
MAPK14 Q16539 P47811 Kinase Cytosol FOS P01100 P01101 TF Nucleus + Phosphorylation 15708845
AXL P30530 Q00993 Receptor Membrane RANBP9 Q96S59 P69566 Adapter Cytosol + Binding 15964779
ILK Q13418 O55222 Kinase Cytosol PPP1R14A Q96A00 Q91VC7 Inhibitor Cytosol + Phosphorylation 12144526
EPB41 P11171 P48193 Adapter Cytosol SPTBN2 O15020 NA Cytoskeleton Cytosol 0 Binding 1647028
EPB41 P11171 P48193 Adapter Cytosol SPTBN2 O15020 NA Cytoskeleton Cytosol 0 Binding 3121803
CALR P27797 P14211 Chaperone ER NASCENTCHAIN NA NA Peptide Ribosomes 0 Binding 7657600
PTK2 Q05397 P34152 Kinase Cytosol FYN P06241 P39688 Kinase Cytosol + Binding 7505391
PTK2 Q05397 P34152 Kinase Cytosol FYN P06241 P39688 Kinase Cytosol + Binding 10085136
EIF4B P23588 Q8BGD9 Ribosome Ribosomes mRNA NA NA RNA Ribosomes 0 Binding 6712925
IQGAP1 P46940 Q9JKF1 GAP Cytosol NRAS P01111 P08556 GTPase Cytosol _ GAP 8670801
PTK2B Q14289 Q9QVP9 Kinase Cytosol EGFR P00533 Q01279 Receptor Membrane + Phosphorylation 11274221
CTNND2 Q9UQB3 O35927 Adapter Cytosol SPHK1 Q9NYA1 NA Kinase Cytosol + Binding 15193146
ARHGEF7 Q14155 Q9ES28 GEF Cytosol CDC42 P60953 P60766 GTPase Cytosol + GEF 9659915
ILK Q13418 O55222 Kinase Cytosol AKT1 P31749 P31750 Kinase Cytosol + Phosphorylation 9736715
SSTR1 P30872 P30873 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 8145728
FBXW7 Q969H0 Q8VBV4 Ubiquitinase Cytosol JUN P05412 P05627 TF Nucleus _ Ubiquitination 16023596
PPP3R1 P63098 Q63810 Phosphatase Cytosol AKAP5 P24588 NA Adapter Cytosol 0 Binding 8599116
PRKCA P17252 P20444 Kinase Cytosol SNAP25 P60880 P60879 Vesicle Vesicles _ Phosphorylation 15277518
PRKCA P17252 P20444 Kinase Cytosol SNAP25 P60880 P60879 Vesicle Vesicles _ Phosphorylation 12417653
PRKCA P17252 P20444 Kinase Cytosol RASGRP3 Q8IV61 NA GEF Cytosol + Phosphorylation 12730099
PRKCA P17252 P20444 Kinase Cytosol RASGRP3 Q8IV61 NA GEF Cytosol + Phosphorylation 15213298
DOCK2 Q92608 Q8C3J5 Vesicle Vesicles UNC13B O14795 Q9Z1N9 Vesicle Vesicles + Binding 11027523
DOCK2 Q92608 Q8C3J5 Vesicle Vesicles UNC13B O14795 Q9Z1N9 Vesicle Vesicles + Binding 10594652
DOCK2 Q92608 Q8C3J5 Vesicle Vesicles UNC13B O14795 Q9Z1N9 Vesicle Vesicles + Binding 9736751
CALCIUM NA NA Messenger Cytosol KCNIP4 Q6PIL6 Q6PHZ8 Adapter Cytosol 0 Binding 15356203
YWHAH Q04917 P68510 Adapter Cytosol CFL1 P23528 P18760 Cytoskeleton Cytosol _ Binding 12361576
CALCIUM NA NA Messenger Cytosol KCNIP3 Q9Y2W7 P0C092 Adapter Cytosol 0 Binding 15356203
CALCIUM NA NA Messenger Cytosol KCNIP3 Q9Y2W7 P0C092 Adapter Cytosol 0 Binding 10078534
CALCIUM NA NA Messenger Cytosol KCNIP3 Q9Y2W7 P0C092 Adapter Cytosol 0 Binding 11535596
CALCIUM NA NA Messenger Cytosol KCNIP2 Q9NS61 Q9JJ69 Adapter Cytosol 0 Binding 15356203
CALCIUM NA NA Messenger Cytosol KCNIP1 Q9NZI2 Q9JJ57 Adapter Cytosol 0 Binding 15356203
GNB2L1 P63244 P68040 Adapter Cytosol FYN P06241 P39688 Kinase Cytosol _ Binding 11943848
NTRK1 P04629 NA Receptor Membrane CHN1 P15882 Q91V57 GAP Cytosol + Binding 12446789
FASLG P48023 P41047 Ligand Extracellular FAS P25445 P25446 Receptor Membrane + Binding 1375228
FASLG P48023 P41047 Ligand Extracellular FAS P25445 P25446 Receptor Membrane + Binding 1713127
FASLG P48023 P41047 Ligand Extracellular FAS P25445 P25446 Receptor Membrane + Binding 7505205
MAPK8 P45983 Q91Y86 Kinase Nucleus YWHAH Q04917 P68510 Adapter Cytosol + Phosphorylation 16009721
CAPZB P47756 P47757 Cytoskeleton Cytosol DNM1 Q05193 P39053 GTPase Vesicles 0 Binding 9463375
MAPK1 P28482 P63085 Kinase Cytosol MARCKS P29966 P26645 Adapter Cytosol + Phosphorylation 9867858
SNAP25 P60880 P60879 Vesicle Vesicles CACNA1B Q00975 O55017 Channel Membrane _ Binding 8559250
SNAP25 P60880 P60879 Vesicle Vesicles CACNA1B Q00975 O55017 Channel Membrane _ Binding 9278528
SNAP25 P60880 P60879 Vesicle Vesicles CACNA1B Q00975 O55017 Channel Membrane _ Binding 11312277
SNAP25 P60880 P60879 Vesicle Vesicles CACNA1A O00555 P97445 Channel Membrane 0 Binding 9593683
PLN P26678 P61014 Pump ER CALCIUM NA NA Messenger Cytosol _ Pumping 15598648
GNB2 P62879 P62880 Gprotein Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 1465133
GNB2 P62879 P62880 Gprotein Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 8387502
GNB2 P62879 P62880 Gprotein Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 8306983
GNB2 P62879 P62880 Gprotein Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 1465134
GNB2 P62879 P62880 Gprotein Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 9307019
KCNIP4 Q6PIL6 Q6PHZ8 Adapter Cytosol KCND2 Q9NZV8 Q9Z0V2 Channel Membrane + Binding 15356203
UBLE1B Q9UBT2 Q9Z1F9 Adapter Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol 0 Binding 10570482
GRIN2A Q12879 P35436 Receptor Membrane CALCIUM NA NA Messenger Cytosol + Opening 3012362
ANP NA NA Ligand Extracellular GUCY1B3 Q02153 O54865 Cyclase Membrane + Binding 2571188
HOMER2 Q9NSB8 Q9QWW1 Adapter Cytosol GRIA1 P42261 P23818 Channel Membrane 0 Binding 9808459
CALM3 P62158 P62204 Activator Cytosol ATP2B1 P20020 NA Pump Membrane + Binding 6455424
CAPN1 P07384 O35350 Protease Cytosol GRIA1 P42261 P23818 Channel Membrane _ Cleavage 11677266
MAPK8 P45983 Q91Y86 Kinase Nucleus BCL2L11 O43521 O54918 Bcl2Family Mitochondria + Phosphorylation 12818176
CALM3 P62158 P62204 Activator Cytosol EEF2K O00418 O08796 GTPase Ribosomes + Binding 3693353
CALM3 P62158 P62204 Activator Cytosol EEF2K O00418 O08796 GTPase Ribosomes + Binding 3906654
DLG4 P78352 Q62108 Adapter Cytosol ACTN3 Q08043 O88990 Cytoskeletal Cytosol 0 Binding 9009191
NTRK2 Q16620 P15209 Receptor Membrane FYN P06241 P39688 Kinase Cytosol + Binding 9648856
SSTR2 P30874 P30875 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 1374909
HDAC3 O15379 O88895 Hdac Nucleus JUN P05412 P05627 TF Nucleus _ Binding 12853483
MAP3K14 Q99558 Q9WUL6 Kinase Cytosol CHUK O15111 Q60680 Kinase Cytosol + Phosphorylation 9244310
KCNJ10 P78508 Q9JM63 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 11169792
NO NA NA Messenger Cytosol GUCY1B3 Q02153 O54865 Cyclase Cytosol + Binding 20623
NO NA NA Messenger Cytosol GUCY1B3 Q02153 O54865 Cyclase Cytosol + Binding 2903071
FYN P06241 P39688 Kinase Cytosol DLG2 Q15700 Q91XM9 Adapter Cytosol 0 Phosphorylation 13129934
CALM3 P62158 P62204 Activator Cytosol MYRIP Q8NFW9 Q8K3I4 Cytoskeleton Cytosol 0 Binding 10336484
CALM3 P62158 P62204 Activator Cytosol MYRIP Q8NFW9 Q8K3I4 Cytoskeleton Cytosol 0 Binding 1469047
DYRK1A Q13627 Q61214 Kinase Cytosol MAPT P10636 P10637 Activator Cytosol _ Phosphorylation 11311121
FAS P25445 P25446 Receptor Membrane FADD Q13158 Q61160 Adapter Cytosol + Binding 8521815
INSR P06213 P15208 Receptor Membrane GRB10 Q13322 Q60760 Adapter Cytosol + Binding 12783867
PIP2 NA NA Lipid Cytosol ATP2B1 P20020 NA Pump Membrane + Binding 11734659
PIP2 NA NA Lipid Cytosol ATP2B1 P20020 NA Pump Membrane + Binding 6455424
PRKCA P17252 P20444 Kinase Cytosol MAP2 P11137 P20357 Cytoskeleton Cytosol + Phosphorylation 2561875
MAPK8 P45983 Q91Y86 Kinase Nucleus MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol + Phosphorylation 16195223
MAP1B P46821 P14873 Activator Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol 0 Binding 10679011
MAP1B P46821 P14873 Activator Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol 0 Binding 11278895
GNAI3 P08754 Q9DC51 Gprotein Cytosol ADCY5 O95622 P84309 Cyclase Membrane _ Binding 8327893
DYRK1A Q13627 Q61214 Kinase Cytosol EIF2S1 P05198 Q6ZWX6 Ribosome Ribosomes _ Phosphorylation 11311121
GNAI3 P08754 Q9DC51 Gprotein Cytosol ADCY2 Q08462 Q80TL1 Cyclase Cytosol _ Binding 8327893
RAPGEF3 O95398 Q8VCC8 GEF Cytosol RAP1A P62834 P62835 GTPase Cytosol + GEF 9853756
MAP3K2 Q9Y2U5 Q61083 Kinase Cytosol MAPK1 P28482 P63085 Kinase Cytosol + Phosphorylation 8226933
DAG NA NA Lipid Cytosol PRKCA P17252 P20444 Kinase Cytosol + Binding 438153
DLG4 P78352 Q62108 Adapter Cytosol ERBB2IP Q96RT1 Q80TH2 Adapter Cytosol 0 Binding 11279080
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol DVL1 O14640 P51141 Adapter Membrane + Phosphorylation 9214626
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol DVL1 O14640 P51141 Adapter Membrane + Phosphorylation 10409711
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol DVL1 O14640 P51141 Adapter Membrane + Phosphorylation 10806215
ANAPC1 Q9H1A4 P53995 Adapter Cytosol CTNNB1 P35222 Q02248 TF Cytosol _ Binding 9556553
ANAPC1 Q9H1A4 P53995 Adapter Cytosol CTNNB1 P35222 Q02248 TF Cytosol _ Binding 8638126
MAPK1 P28482 P63085 Kinase Cytosol JUN P05412 P05627 TF Nucleus _ Phosphorylation 7935387
CREBBP Q92793 P45481 TF Nucleus TCF7 P36402 Q00417 TF Nucleus _ Binding 9388250
CREBBP Q92793 P45481 TF Nucleus TCF7 P36402 Q00417 TF Nucleus _ Binding 9774110
SEC63 Q9UGP8 Q8VHE0 Adapter ER HSPA5 P11021 P20029 Chaperone ER + Binding 10400622
ACTB P60709 P60710 Cytoskeleton Cytosol SPTBN2 O15020 NA Cytoskeleton Cytosol 0 Binding 1647028
ARRB1 P49407 Q8BWG8 Adapter Cytosol OPRM1 P35372 P42866 Receptor Cytosol _ Binding 11861651
HPCA P84074 P84075 Adapter Cytosol BIRC1 Q13075 NA Inhibitor Cytosol + Binding 15280366
HPCA P84074 P84075 Adapter Cytosol BIRC1 Q13075 NA Inhibitor Cytosol + Binding 10899114
BRRN1 Q15003 Q8C156 Adapter Cytosol ACTN3 Q08043 O88990 Cytoskeleton Cytosol 0 Binding 11160423
JUN P05412 P05627 TF Nucleus CREB1 P16220 Q01147 TF Nucleus + Binding 1827203
RAC1 P63000 P63001 GTPase Cytosol PAK1 Q13153 O88643 Kinase Cytosol + Binding 8107774
VAV1 P15498 P27870 GEF Cytosol ARHGAP1 Q07960 NA GTPase Cytosol + GEF 9822605
VAV1 P15498 P27870 GEF Cytosol ARHGAP1 Q07960 NA GTPase Cytosol + GEF 9032261
VAV1 P15498 P27870 GEF Cytosol ARHGAP1 Q07960 NA GTPase Cytosol + GEF 8994827
PIP2 NA NA Lipid Membrane AKT1 P31749 P31750 Kinase Cytosol + Binding 9445477
IRS1 P35568 P35569 Adapter Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 1381348
IRS1 P35568 P35569 Adapter Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 1380456
IRS1 P35568 P35569 Adapter Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 9374521
CREB1 P16220 Q01147 TF Nucleus TAF1 P21675 NA TF Nucleus + Binding 7906413
CREB1 P16220 Q01147 TF Nucleus TAF1 P21675 NA TF Nucleus + Binding 7615553
CSK P41240 P41241 Kinase Cytosol PXN P49023 Q8VI36 Adapter Cytosol + Phosphorylation 9890993
SS NA NA Ligand Extracellular SSTR2 P30874 P30875 Receptor Membrane + Binding 15181094
SS NA NA Ligand Extracellular SSTR2 P30874 P30875 Receptor Membrane + Binding 1346068
PTPRA P18433 P18052 Phosphatase Cytosol FYN P06241 P39688 Kinase Cytosol + Dephosphorylation 9535845
PTPRA P18433 P18052 Phosphatase Cytosol FYN P06241 P39688 Kinase Cytosol + Dephosphorylation 10562275
DFFA O00273 O54786 Inhibitor Cytosol DFFB O76075 O54788 DNase Nucleus _ Binding 9422513
DFFA O00273 O54786 Inhibitor Cytosol DFFB O76075 O54788 DNase Nucleus _ Binding 12655299
SS NA NA Ligand Extracellular SSTR1 P30872 P30873 Receptor Membrane + Binding 8145728
SS NA NA Ligand Extracellular SSTR1 P30872 P30873 Receptor Membrane + Binding 1346068
PPP2R5C Q13362 Q60996 Phosphatase Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Dephosphorylation 8183343
STX3 Q13277 Q64704 Vesicle Vesicles CACNA1B Q00975 O55017 Channel Membrane _ Binding 10692440
STX3 Q13277 Q64704 Vesicle Vesicles CACNA1B Q00975 O55017 Channel Membrane _ Binding 7993624
STX3 Q13277 Q64704 Vesicle Vesicles CACNA1B Q00975 O55017 Channel Membrane _ Binding 8559250
STX3 Q13277 Q64704 Vesicle Vesicles CACNA1B Q00975 O55017 Channel Membrane _ Binding 9278528
STX3 Q13277 Q64704 Vesicle Vesicles CACNA1B Q00975 O55017 Channel Membrane _ Binding 8524397
STX3 Q13277 Q64704 Vesicle Vesicles CACNA1B Q00975 O55017 Channel Membrane _ Binding 10844004
STX3 Q13277 Q64704 Vesicle Vesicles CACNA1A O00555 P97445 Channel Membrane 0 Binding 8524397
STX3 Q13277 Q64704 Vesicle Vesicles CACNA1A O00555 P97445 Channel Membrane 0 Binding 9593683
GRM7 Q14831 Q68ED2 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 10488094
NRAS P01111 P08556 GTPase Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 9150145
NRAS P01111 P08556 GTPase Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 7820549
NRAS P01111 P08556 GTPase Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 8052307
SYN1 P17600 O88935 Vesicle Vesicles GNAZ P19086 O70443 Gprotein Cytosol _ Binding 14557263
CALCIUM NA NA Messenger Cytosol SV2A Q7L0J3 Q9JIS5 Vesicle Vesicles _ Binding 8910372
ITCH Q96J02 Q8C863 E3Ligase Cytosol JUNB P17275 P09450 TF Nucleus _ Ubiquitination 16387660
CDK5 Q00535 P49615 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles 0 Phosphorylation 8702879
GRIN2A Q12879 P35436 Receptor Membrane TUBA3 Q71U36 NA Cytoskeleton Cytosol 0 Binding 10037467
MAPK8 P45983 Q91Y86 Kinase Nucleus TP53BP1 Q12888 P70399 TF Nucleus + Phosphorylation 9050839
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol FYN P06241 P39688 Kinase Cytosol _ Binding 8083187
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol FYN P06241 P39688 Kinase Cytosol _ Binding 15208330
MAPK14 Q16539 P47811 Kinase Cytosol NFATC1 O95644 O88942 TF Nucleus _ Phosphorylation 10788511
MAPK14 Q16539 P47811 Kinase Cytosol NFATC1 O95644 O88942 TF Nucleus _ Phosphorylation 11997522
PRKCA P17252 P20444 Kinase Cytosol ABL1 P00519 P00520 Kinase Cytosol + Phosphorylation 10713049
DLG4 P78352 Q62108 Adapter Cytosol UBLE1B Q9UBT2 Q9Z1F9 Adapter Cytosol 0 Binding 9581762
DLG4 P78352 Q62108 Adapter Cytosol UBLE1B Q9UBT2 Q9Z1F9 Adapter Cytosol 0 Binding 10570482
PDPK1 O15530 Q9Z2A0 Kinase Cytosol PRKCA P17252 P20444 Kinase Cytosol + Phosphorylation 9889098
CAMK2A Q9UQM7 P11798 Kinase Cytosol TIAM1 Q13009 Q60610 GEF Cytosol + Phosphorylation 10212259
DLG4 P78352 Q62108 Adapter Cytosol MALS NA NA Adapter Cytosol 0 Binding 10341223
CAMK2A Q9UQM7 P11798 Kinase Cytosol RASGRF1 Q13972 P27671 GEF Cytosol + Phosphorylation 9281359
GAB1 Q13480 Q9QYY0 Adapter Cytosol PXN P49023 Q8VI36 Adapter Cytosol 0 Binding 14665621
PIP2 NA NA Lipid Cytosol PSCD2 Q99418 P63034 GEF Cytosol + Binding 9268368
PIP2 NA NA Lipid Cytosol PSCD2 Q99418 P63034 GEF Cytosol + Binding 10801341
TLN1 Q9Y490 P26039 Cytoskeleton Cytosol ITGB1 P05556 P09055 CellAdhesion Membrane 0 Binding 7716514
TLN1 Q9Y490 P26039 Cytoskeleton Cytosol ITGB1 P05556 P09055 CellAdhesion Membrane 0 Binding 3124107
SYN1 P17600 O88935 Vesicle Vesicles SRC P12931 P05480 Kinase Cytosol 0 Binding 9539797
MAPK8 P45983 Q91Y86 Kinase Nucleus IRS1 P35568 P35569 Adapter Cytosol _ Phosphorylation 16055440
PAK1 Q13153 O88643 Kinase Cytosol LIMK1 P53667 P53668 Kinase Cytosol + Phosphorylation 11413130
PAK1 Q13153 O88643 Kinase Cytosol LIMK1 P53667 P53668 Kinase Cytosol + Phosphorylation 10559936
NRGN Q92686 P60761 Inhibitor Cytosol CALM3 P62158 P62204 Activator Cytosol _ Binding 1824695
LYN P07948 P25911 Kinase Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol + Phosphorylation 7678277
TUBA3 Q71U36 NA Cytoskeleton Cytosol ARHGEF2 Q92974 Q60875 Adapter Cytosol 0 Binding 9857026
ITPR1 Q14643 P11881 Channel ER CALCIUM NA NA Messenger Cytosol + Opening 2847175
ITPR1 Q14643 P11881 Channel ER CALCIUM NA NA Messenger Cytosol + Opening 3027583
S40 NA NA Ribosome Ribosomes EIF3S1 O75822 Q66JS6 Ribosome Ribosomes 0 Binding 6414530
GRM7 Q14831 Q68ED2 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 10488094
PIP3 NA NA Lipid Membrane VAV1 P15498 P27870 GEF Cytosol + Binding 9438848
ARRB1 P49407 Q8BWG8 Adapter Cytosol PDE4D Q08499 Q01063 PDE Cytosol + Binding 12399592
ARRB1 P49407 Q8BWG8 Adapter Cytosol PDE4D Q08499 Q01063 PDE Cytosol + Binding 12552097
AP2S1 P53680 P62743 Adapter Vesicles SYT1 P21579 P46096 Vesicle Vesicles 0 Binding 8087843
SDCBP O00560 O08992 Adapter Cytosol GRM7 Q14831 Q68ED2 Receptor Membrane 0 Binding 11891216
GUCY1B3 Q02153 O54865 Cyclase Cytosol cGMP NA NA Messenger Cytosol + Synthesis 7908417
GUCY1B3 Q02153 O54865 Cyclase Cytosol cGMP NA NA Messenger Cytosol + Synthesis 4982201
PPP3R1 P63098 Q63810 Phosphatase Cytosol NFATC1 O95644 O88942 TF Nucleus _ Dephosphorylation 15743762
PPP3R1 P63098 Q63810 Phosphatase Cytosol NFATC1 O95644 O88942 TF Nucleus _ Dephosphorylation 8631904
PPP3R1 P63098 Q63810 Phosphatase Cytosol NFATC1 O95644 O88942 TF Nucleus _ Dephosphorylation 15364589
LCK P06239 P06240 Kinase Cytosol SOS1 Q07889 Q62245 GEF Cytosol 0 Binding 9856337
MINK1 Q8N4C8 Q9JM52 Kinase Cytosol MAPK14 Q16539 P47811 Kinase Cytosol + Phosphorylation 8626699
MINK1 Q8N4C8 Q9JM52 Kinase Cytosol MAPK14 Q16539 P47811 Kinase Cytosol + Phosphorylation 8622669
MAP3K14 Q99558 Q9WUL6 Kinase Cytosol NCK1 P16333 NA Adapter Cytosol + Binding 9135144
RIMS1 Q86UR5 Q99NE5 Adapter Vesicles SYT1 P21579 P46096 Vesicle Vesicles + Binding 11438518
CACNA1C Q13936 Q01815 Channel Membrane CALCIUM NA NA Messenger Cytosol + Opening 2449181
CACNA1C Q13936 Q01815 Channel Membrane CALCIUM NA NA Messenger Cytosol + Opening 1188153
CASP3 P42574 P70677 Protease Cytosol PARP1 P09874 P11103 Polymerase Cytosol _ Cleavage 10438458
PRKCZ Q05513 Q02956 Kinase Cytosol IKBKB O14920 O88351 Kinase Cytosol + Phosphorylation 10022904
FYN P06241 P39688 Kinase Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol + Phosphorylation 7678277
CACNA1B Q00975 O55017 Channel Membrane CALCIUM NA NA Messenger Cytosol + Opening 1334419
CACNA1B Q00975 O55017 Channel Membrane CALCIUM NA NA Messenger Cytosol + Opening 8386525
CFL1 P23528 P18760 Cytoskeleton Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol _ Binding 10980704
CFL1 P23528 P18760 Cytoskeleton Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol _ Binding 15364581
CACNA1A O00555 P97445 Channel Membrane CALCIUM NA NA Messenger Cytosol + Opening 1651493
CACNA1A O00555 P97445 Channel Membrane CALCIUM NA NA Messenger Cytosol + Opening 10321243
ITSN1 Q15811 Q9Z0R4 Adapter Vesicles SOS1 Q07889 Q62245 GEF Cytosol + Binding 10896662
SNPH O15079 NA Vesicle Vesicles STX3 Q13277 Q64704 Vesicle Vesicles _ Binding 10707983
ILK Q13418 O55222 Kinase Cytosol GSK3A P49840 NA Kinase Cytosol _ Phosphorylation 9736715
CREBBP Q92793 P45481 TF Nucleus STAT1 P42224 P42225 TF Nucleus 0 Binding 8848048
PDGFRB P09619 P05622 Receptor Membrane APS O14492 Q9JID9 Adapter Cytosol + Binding 9989826
PDE3B Q13370 Q61409 PDE Cytosol CAMP P49913 P51437 Messenger Cytosol _ PDE 8395509
INSULIN NA NA Ligand Extracellular INSR P06213 P15208 Receptor Membrane + Binding 6986652
INSULIN NA NA Ligand Extracellular INSR P06213 P15208 Receptor Membrane + Binding 2983222
INSULIN NA NA Ligand Extracellular INSR P06213 P15208 Receptor Membrane + Binding 205798
PIP2 NA NA Lipid Cytosol PLD2 O14939 P97813 Phospholipase Cytosol + Binding 9582313
BRRN1 Q15003 Q8C156 Adapter Cytosol CAMK2A Q9UQM7 P11798 Kinase Cytosol 0 Binding 11160423
BRRN1 Q15003 Q8C156 Adapter Cytosol CAMK2A Q9UQM7 P11798 Kinase Cytosol 0 Binding 10827168
SIPA1 Q96FS4 P46062 GAP Cytosol RAP1A P62834 P62835 GTPase Cytosol _ GAP 12059963
RASGRP3 Q8IV61 NA GEF Cytosol RAP1A P62834 P62835 GTPase Cytosol + GEF 10934204
ANANDAMIDE NA NA Ligand Extracellular CNR2 P34972 P47936 Receptor Membrane + Binding 15082510
ANANDAMIDE NA NA Ligand Extracellular CNR1 P21554 P47746 Receptor Membrane + Binding 15082510
YWHAH Q04917 P68510 Adapter Cytosol TP53BP1 Q12888 P70399 TF Nucleus + Binding 9620776
CALCIUM NA NA Messenger Cytosol CALM3 P62158 P62204 Activator Cytosol + Binding 7356670
CALM3 P62158 P62204 Activator Cytosol MYLK Q15746 Q6PDN3 Kinase Cytosol + Binding 6893940
CALM3 P62158 P62204 Activator Cytosol MYLK Q15746 Q6PDN3 Kinase Cytosol + Binding 6934518
ELK1 P19419 P41969 TF Nucleus SRE NA NA DNA Nucleus + Binding 1722028
ELK1 P19419 P41969 TF Nucleus SRE NA NA DNA Nucleus + Binding 8614640
PIP3 NA NA Lipid Cytosol ILK Q13418 O55222 Kinase Cytosol + Binding 9736715
GNAQ P50148 P21279 Gprotein Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 1846707
GNAQ P50148 P21279 Gprotein Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 1322796
GNAQ P50148 P21279 Gprotein Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 1309799
GNAQ P50148 P21279 Gprotein Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 8387502
GNB2 P62879 P62880 Gprotein Cytosol KCNJ3 P48549 P63250 Channel Membrane + Binding 2433589
GNB2 P62879 P62880 Gprotein Cytosol KCNJ3 P48549 P63250 Channel Membrane + Binding 8145826
YWHAH Q04917 P68510 Adapter Cytosol FOXO3A O43524 NA TF Nuclleus _ Binding 16009721
EGFR P00533 Q01279 Receptor Membrane EPB41 P11171 P48193 Adapter Cytosol + Phosphorylation 1647028
RANBP9 Q96S59 P69566 Adapter Cytosol RAN P62826 P62827 GTPase Nucleus + Binding 9817760
RANBP9 Q96S59 P69566 Adapter Cytosol RAN P62826 P62827 GTPase Nucleus + Binding 11470507
PRKCA P17252 P20444 Kinase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Phosphorylation 7935389
PRKCA P17252 P20444 Kinase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Phosphorylation 9447975
PRKCA P17252 P20444 Kinase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Phosphorylation 1437148
PRKCA P17252 P20444 Kinase Cytosol GSK3A P49840 NA Kinase Cytosol _ Phosphorylation 1324914
PRKCA P17252 P20444 Kinase Cytosol GSK3A P49840 NA Kinase Cytosol _ Phosphorylation 14556709
KCNIP2 Q9NS61 Q9JJ69 Adapter Cytosol KCND2 Q9NZV8 Q9Z0V2 Channel Membrane 0 Binding 15356203
PRKCA P17252 P20444 Kinase Cytosol PLAA Q9Y263 P27612 Phospholipase Cytosol + Phosphorylation 12423237
PRKCA P17252 P20444 Kinase Cytosol SRF P11831 NA TF Nucleus + Phosphorylation 12809504
DVL1 O14640 P51141 Adapter Membrane AXIN1 O15169 O35625 Adapter Cytosol _ Binding 11027605
DVL1 O14640 P51141 Adapter Membrane AXIN1 O15169 O35625 Adapter Cytosol _ Binding 10862053
DVL1 O14640 P51141 Adapter Membrane AXIN1 O15169 O35625 Adapter Cytosol _ Binding 10330181
PRKACA P17612 P05132 Kinase Cytosol GABRA1 P14867 P62812 Receptor Membrane _ Phosphorylation 2176510
PRKACA P17612 P05132 Kinase Cytosol GABRA1 P14867 P62812 Receptor Membrane _ Phosphorylation 1321150
PRKACA P17612 P05132 Kinase Cytosol GABRA1 P14867 P62812 Receptor Membrane _ Phosphorylation 1323140
YWHAH Q04917 P68510 Adapter Cytosol FOXO1A Q12778 Q9R1E0 TF Nucleus _ Binding 14690436
PLCG1 P19174 Q62077 Phospholipase Cytosol SYN1 P17600 O88935 Vesicle Vesicles 0 Binding 10899172
AKAP9 Q99996 NA Adapter Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol 0 Binding 10390370
PDE1A P54750 Q61481 PDE Cytosol cGMP NA NA Messenger Cytosol _ PDE 7678006
PDE1A P54750 Q61481 PDE Cytosol cGMP NA NA Messenger Cytosol _ PDE 1326531
PDE1A P54750 Q61481 PDE Cytosol cGMP NA NA Messenger Cytosol _ PDE 8537356
CALM3 P62158 P62204 Activator Cytosol RYR1 P21817 NA Channel ER + Binding 8035880
MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol DLK1 P80370 Q09163 Kinase Cytosol + Binding 9733513
IGF1R P08069 Q60751 Receptor Cytosol VAV1 P15498 P27870 GEF Cytosol + Phosphorylation 11094073
MAPK14 Q16539 P47811 Kinase Cytosol STAT1 P42224 P42225 TF Nucleus + Phosphorylation 10201984
MAPK1 P28482 P63085 Kinase Cytosol SF1 Q15637 Q64213 Adapter Cytosol + Phosphorylation 12478298
PPP2R5C Q13362 Q60996 Phosphatase Cytosol CREB1 P16220 Q01147 TF Nucleus _ Dephosphorylation 8386317
PPP2R5C Q13362 Q60996 Phosphatase Cytosol CREB1 P16220 Q01147 TF Nucleus _ Dephosphorylation 8195196
ADENOSINE NA NA Ligand Extracellular ADORA2A P29274 Q60613 Receptor Membrane + Binding 2541503
ADENOSINE NA NA Ligand Extracellular ADORA2A P29274 Q60613 Receptor Membrane + Binding 2125216
ARF1 P84077 P84078 GTPase Vesicles PLD2 O14939 P97813 Phospholipase Cytosol + Binding 9582313
RAPGEF1 Q13905 NA GEF Cytosol RAP1A P62834 P62835 GTPase Cytosol + GEF 9560161
RAPGEF1 Q13905 NA GEF Cytosol RAP1A P62834 P62835 GTPase Cytosol + GEF 8524240
EIF4G2 P78344 Q62448 Ribosome Ribosomes PABPC1 P11940 P29341 Adapter Ribosomes 0 Binding 10944120
EIF4G2 P78344 Q62448 Ribosome Ribosomes PABPC1 P11940 P29341 Adapter Ribosomes 0 Binding 9195926
YWHAH Q04917 P68510 Adapter Cytosol IRS1 P35568 P35569 Adapter Cytosol _ Binding 9312143
SNAP25 P60880 P60879 Vesicle Vesicles ADCY5 O95622 P84309 Cyclase Membrane + Binding 15319443
GRIA1 P42261 P23818 Channel Membrane GCC1 Q96CN9 Q9D4H2 Adapter Cytosol 0 Binding 9069286
GNB2 P62879 P62880 Gprotein Cytosol CACNA1B Q00975 O55017 Channel Membrane _ Binding 9009193
GNB2 P62879 P62880 Gprotein Cytosol CACNA1B Q00975 O55017 Channel Membrane _ Binding 10692440
GNB2 P62879 P62880 Gprotein Cytosol CACNA1B Q00975 O55017 Channel Membrane _ Binding 11086994
GNB2 P62879 P62880 Gprotein Cytosol CACNA1A O00555 P97445 Channel Membrane + Binding 9009193
MAPK8 P45983 Q91Y86 Kinase Nucleus ELK1 P19419 P41969 TF Nucleus + Phosphorylation 9407028
MAPK8 P45983 Q91Y86 Kinase Nucleus ELK1 P19419 P41969 TF Nucleus + Phosphorylation 8846788
MAPK8 P45983 Q91Y86 Kinase Nucleus ELK1 P19419 P41969 TF Nucleus + Phosphorylation 9501095
ROCK2 O75116 P70336 Kinase Cytosol CAPZB P47756 P47757 Cytoskeleton Cytosol + Phosphorylation 14517206
GNB2 P62879 P62880 Gprotein Cytosol KCNA1 Q09470 P16388 Channel Membrane + Binding 12114518
CASP3 P42574 P70677 Protease Cytosol PIP5K2A P48426 O70172 Kinase Cytosol _ Cleavage 11042212
SUMO2 P61956 P61957 Sumo Cytosol JUN P05412 P05627 TF Nucleus _ Sumolation 16055710
ACTB P60709 P60710 Cytoskeleton Cytosol TLN1 Q9Y490 P26039 Cytoskeleton Cytosol 0 Binding 2121138
NOS1 P29475 Q9Z0J4 Synthase Cytosol DLG2 Q15700 Q91XM9 Adapter Cytosol 0 Binding 8922396
PIK3CA P42336 P42337 Kinase Cytosol TOM1L1 O75674 Q923U0 Adapter Cytosol 0 Binding 11711534
CALM3 P62158 P62204 Activator Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Binding 12379661
CALM3 P62158 P62204 Activator Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Binding 9952395
CALM3 P62158 P62204 Activator Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Binding 8625412
CALM3 P62158 P62204 Activator Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Binding 9728925
BIRC5 O15392 O70201 Inhibitor Cytosol CASP7 P55210 P97864 Protease Cytosol _ Binding 9384571
CALCIUM NA NA Messenger Cytosol CALB1 P05937 P12658 Adapter Cytosol + Binding 3691519
BIRC5 O15392 O70201 Inhibitor Cytosol CASP3 P42574 P70677 Protease Cytosol _ Binding 9384571
BAX Q07812 Q07813 Bcl2Family Mitochondria BAD Q92934 Q61337 Bcl2Family Mitochondria _ Binding 9388232
SYT1 P21579 P46096 Vesicle Vesicles SNAP25 P60880 P60879 Vesicle Vesicles 0 Binding 1470954
CALM3 P62158 P62204 Activator Cytosol RAB3A P20336 P63011 GTPase Vesicles _ Binding 9252412
GRIN2A Q12879 P35436 Receptor Membrane DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 11677266
GRIN2A Q12879 P35436 Receptor Membrane DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 12399578
GRIN2A Q12879 P35436 Receptor Membrane DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 7569905
GRIN2A Q12879 P35436 Receptor Membrane DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 8922396
GRIN2A Q12879 P35436 Receptor Membrane DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 11937501
GRIN2A Q12879 P35436 Receptor Membrane DLG3 Q92796 P70175 Adapter Cytosol + Binding 11937501
GRIN2A Q12879 P35436 Receptor Membrane DLG2 Q15700 Q91XM9 Adapter Cytosol 0 Binding 8922396
GRIN2A Q12879 P35436 Receptor Membrane DLG2 Q15700 Q91XM9 Adapter Cytosol 0 Binding 8755482
GRIN2A Q12879 P35436 Receptor Membrane DLG1 Q12959 Q811D0 Adapter Cytosol 0 Binding 10336672
MAPK14 Q16539 P47811 Kinase Cytosol MEF2B Q02080 O55087 TF Nucleus + Phosphorylation 10531066
DRD3 P35462 P30728 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 15102843
EIF5 P55010 P59325 Ribosome Ribosomes EIF2S1 P05198 Q6ZWX6 Ribosome Ribosomes + Binding 9395514
BDNF P23560 P21237 Ligand Extracellular NTRK2 Q16620 P15209 Receptor Membrane + Binding 9648856
BDNF P23560 P21237 Ligand Extracellular NTRK2 Q16620 P15209 Receptor Membrane + Binding 1645620
CALM3 P62158 P62204 Activator Cytosol PPP3R1 P63098 Q63810 Phosphatase Cytosol + Binding 293720
GAB1 Q13480 Q9QYY0 Adapter Cytosol PIK3CA P42336 P42337 Kinase Cytosol + Binding 8596638
PDE4A P27815 O89084 PDE Cytosol CAMP P49913 P51437 Messenger Cytosol _ PDE 7702577
PDE4A P27815 O89084 PDE Cytosol CAMP P49913 P51437 Messenger Cytosol _ PDE 2542941
AXIN1 O15169 O35625 Adapter Cytosol CTNNB1 P35222 Q02248 TF Cytosol _ Binding 10196136
AXIN1 O15169 O35625 Adapter Cytosol CTNNB1 P35222 Q02248 TF Cytosol _ Binding 9482734
AXIN1 O15169 O35625 Adapter Cytosol CTNNB1 P35222 Q02248 TF Cytosol _ Binding 9501208
AXIN1 O15169 O35625 Adapter Cytosol CTNNB1 P35222 Q02248 TF Cytosol _ Binding 9601641
CALCIUM NA NA Messenger Cytosol FREQ P62166 Q8BNY6 Adapter Cytosol + Binding 7806504
FRK P42685 NA Kinase Cytosol FOS P01100 P01101 TF Nucleus + Phosphorylation 8072547
PPP5C P53041 Q60676 Phosphatase Cytosol MAPT P10636 P10637 Activator Cytosol _ Dephosphorylation 14690518
RANBP9 Q96S59 P69566 Adapter Cytosol USP11 P51784 Q99K46 Hydrolase Cytosol 0 Deubiquitination 12084015
TUBA3 Q71U36 NA Cytoskeleton Cytosol PIK3CA P42336 P42337 Kinase Cytosol 0 Binding 8910394
NOS1 P29475 Q9Z0J4 Synthase Cytosol NO NA NA Messenger Cytosol + Synthesis 7528745
NOS1 P29475 Q9Z0J4 Synthase Cytosol NO NA NA Messenger Cytosol + Synthesis 1722402
IP3 NA NA Lipid Cytosol ITPR1 Q14643 P11881 Channel ER + Binding 1374893
IP3 NA NA Lipid Cytosol ITPR1 Q14643 P11881 Channel ER + Binding 2826483
IP3 NA NA Lipid Cytosol ITPR1 Q14643 P11881 Channel ER + Binding 3027583
IP3 NA NA Lipid Cytosol ITPR1 Q14643 P11881 Channel ER + Binding 2847175
ATP2B1 P20020 NA Pump Membrane CALCIUM NA NA Messenger Cytosol _ Pumping 6455424
CHRM2 P08172 Q9ERZ4 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 8786435
CHRM2 P08172 Q9ERZ4 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 3037705
CAMK2A Q9UQM7 P11798 Kinase Cytosol VAPA Q9P0L0 Q9WV55 Vesicle Vesicles 0 Phosphorylation 8876242
CALM3 P62158 P62204 Activator Cytosol IQGAP1 P46940 Q9JKF1 GAP Cytosol + Binding 8670801
CALM3 P62158 P62204 Activator Cytosol IQGAP1 P46940 Q9JKF1 GAP Cytosol + Binding 11809768
RGS2 P41220 O08849 Gprotein Cytosol GNAI3 P08754 Q9DC51 Gprotein Cytosol _ GAP 9736641
PRKACA P17612 P05132 Kinase Cytosol CREBBP Q92793 P45481 TF Nucleus + Phosphorylation 15299023
GRB2 P62993 Q60631 Adapter Cytosol SPRY1 O43609 Q9QXV9 Adapter Cytosol 0 Binding 15031289
FADD Q13158 Q61160 Adapter Cytosol CASP8 Q14790 O89110 Protease Cytosol + Binding 8681377
RPS6KA1 Q15418 P18653 Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 8688081
PTEN P60484 O08586 Phosphatase Cytosol PIP3 NA NA Lipid Cytosol _ Dephosphorylation 10716737
PPP3R1 P63098 Q63810 Phosphatase Cytosol PTPN5 P54829 P54830 Phosphatase Cytosol + Dephosphorylation 12483215
SODIUM NA NA Ion Cytosol SLC1A3 P43003 P56564 Transporter Membrane + Binding 7679914
GSK3A P49840 NA Kinase Cytosol MYC P01106 P01108 TF Nucleus _ Phosphorylation 16023596
cADPR NA NA Messenger Cytosol RYR1 P21817 NA Channel ER + Binding 8391127
PRKCA P17252 P20444 Kinase Cytosol EGFR P00533 Q01279 Receptor Membrane _ Phosphorylation 6321473
NLGN1 Q8N2Q7 Q99K10 CellAdhesion Membrane SSCAM NA NA Adapter Cytosol 0 Binding 9694864
GSK3A P49840 NA Kinase Cytosol PSEN1 P49768 P49769 Protease Membrane _ Phosphorylation 9689133
GSK3A P49840 NA Kinase Cytosol PSEN1 P49768 P49769 Protease Membrane _ Phosphorylation 11104755
CASP9 P55211 NA Protease Cytosol CASP7 P55210 P97864 Protease Cytosol + Cleavage 9651578
CASP9 P55211 NA Protease Cytosol CASP6 P55212 O08738 Protease Cytosol + Cleavage 9651578
CASP9 P55211 NA Protease Cytosol CASP6 P55212 O08738 Protease Cytosol + Cleavage 12097334
CASP9 P55211 NA Protease Cytosol CASP3 P42574 P70677 Protease Cytosol + Cleavage 9390557
AKT1 P31749 P31750 Kinase Cytosol TP53BP1 Q12888 P70399 TF Nucleus _ Phosphorylation 11054421
S40 NA NA Ribosome Ribosomes SEC61A1 P61619 P61620 Channel ER 0 Binding 11036067
TOM1L1 O75674 Q923U0 Adapter Cytosol FYN P06241 P39688 Kinase Cytosol + Binding 11711534
INADL Q8NI35 Q63ZW7 Adapter Cytosol KCNJ10 P78508 Q9JM63 Channel Membrane 0 Binding 9647694
RALA P11233 P63321 GTPase Cytosol RALBP1 Q15311 Q62172 GAP Cytosol + Binding 10393179
RALA P11233 P63321 GTPase Cytosol RALBP1 Q15311 Q62172 GAP Cytosol + Binding 7623849
CHN1 P15882 Q91V57 GAP Cytosol ARHGAP1 Q07960 NA GTPase Cytosol _ GAP 12446789
HGS O14964 Q99LI8 Vesicle Vesicles SNAP25 P60880 P60879 Vesicle Vesicles _ Binding 9039916
IQGAP1 P46940 Q9JKF1 GAP Cytosol CTNNB1 P35222 Q02248 TF Cytosol 0 Binding 9694656
IQGAP1 P46940 Q9JKF1 GAP Cytosol CTNNB1 P35222 Q02248 TF Cytosol 0 Binding 10473551
SHANK1 Q9Y566 NA Adapter Cytosol HOMER2 Q9NSB8 Q9QWW1 Adapter Cytosol 0 Binding 10433269
TRADD Q15628 NA Adapter Cytosol FADD Q13158 Q61160 Adapter Cytosol + Binding 8565075
YWHAH Q04917 P68510 Adapter Cytosol NFATC1 O95644 O88942 TF Nucleus _ Binding 10611249
ARHGEF7 Q14155 Q9ES28 GEF Cytosol ARHGAP1 Q07960 NA GTPase Cytosol + Binding 9659915
KCNJ2 P63252 P35561 Channel Membrane DLG2 Q15700 Q91XM9 Adapter Cytosol 0 Binding 8755482
KCNJ2 P63252 P35561 Channel Membrane DLG2 Q15700 Q91XM9 Adapter Cytosol 0 Binding 15304517
ARRB1 P49407 Q8BWG8 Adapter Cytosol SRC P12931 P05480 Kinase Cytosol + Binding 10753943
CERAMIDE NA NA Lipid Cytosol CERK Q8TCT0 Q8K4Q7 Kinase Cytosol + Binding 7477354
MAP3K14 Q99558 Q9WUL6 Kinase Cytosol MAP3K1 Q13233 P53349 Kinase Cytosol + Binding 9135144
SRC P12931 P05480 Kinase Cytosol SPTBN2 O15020 NA Cytoskeleton Cytosol + Phosphorylation 12446661
SUMO1 P63165 P63166 Sumo Cytosol FOS P01100 P01101 TF Nucleus _ Sumolation 16055710
PIP2 NA NA Lipid Cytosol RPH3A Q9Y2J0 P47708 Vesicle Vesicles + Binding 8262955
PRKD1 Q15139 Q62101 Kinase Cytosol YWHAH Q04917 P68510 Adapter Cytosol + Phosphorylation 11784866
PRKCA P17252 P20444 Kinase Cytosol MARCKS P29966 P26645 Adapter Cytosol _ Phosphorylation 6957862
PRKCA P17252 P20444 Kinase Cytosol MARCKS P29966 P26645 Adapter Cytosol _ Phosphorylation 15316066
PRKCA P17252 P20444 Kinase Cytosol MARCKS P29966 P26645 Adapter Cytosol _ Phosphorylation 1560845
CALCIUM NA NA Messenger Cytosol DOCK2 Q92608 Q8C3J5 Vesicle Vesicles + Binding 11027523
CALCIUM NA NA Messenger Cytosol DOCK2 Q92608 Q8C3J5 Vesicle Vesicles + Binding 10865129
CALCIUM NA NA Messenger Cytosol DOCK2 Q92608 Q8C3J5 Vesicle Vesicles + Binding 10594652
STAT5A P42229 P42230 TF Nucleus CREBBP Q92793 P45481 TF Nucleus 0 Binding 9037008
STAT5A P42229 P42230 TF Nucleus CREBBP Q92793 P45481 TF Nucleus 0 Binding 9773981
CANX P27824 P35564 Chaperone ER NASCENTCHAIN NA NA Peptide Ribosomes 0 Binding 8486646
ARHGEF2 Q92974 Q60875 Adapter Cytosol ARHGAP1 Q07960 NA GTPase Cytosol + GEF 9857026
cGMP NA NA Messenger Cytosol PRKG2 Q13237 Q61410 Kinase Cytosol + Binding 7908417
cGMP NA NA Messenger Cytosol PRKG2 Q13237 Q61410 Kinase Cytosol + Binding 5445796
cGMP NA NA Messenger Cytosol PRKG2 Q13237 Q61410 Kinase Cytosol + Binding 4331636
ARHGEF1 Q92888 Q61210 GEF Cytosol ARHGAP1 Q07960 NA GTPase Cytosol + GEF 8810315
CALCIUM NA NA Messenger Cytosol HPCA P84074 P84075 Adapter Cytosol + Binding 8166736
CALCIUM NA NA Messenger Cytosol HPCA P84074 P84075 Adapter Cytosol + Binding 1280427
PPM1A P35813 P49443 Phosphatase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria + Dephosphorylation 12590938
MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol TIAM1 Q13009 Q60610 GEF Cytosol + Binding 12024021
GRIK1 P39086 Q60934 Channel Membrane PICK1 Q9NRD5 Q62083 Adapter Cytosol 0 Binding 12597860
GRIK1 P39086 Q60934 Channel Membrane PICK1 Q9NRD5 Q62083 Adapter Cytosol 0 Binding 11891216
SLC6A9 P48067 P28571 Transporter Membrane GLYCINE NA NA Ligand Extracellular _ Importing 9861038
SLC6A9 P48067 P28571 Transporter Membrane GLYCINE NA NA Ligand Extracellular _ Importing 8183239
SLC6A9 P48067 P28571 Transporter Membrane GLYCINE NA NA Ligand Extracellular _ Importing 8494645
SRC P12931 P05480 Kinase Cytosol ADRBK1 P25098 Q99MK8 Kinase Cytosol + Phosphorylation 11278940
CALM3 P62158 P62204 Activator Cytosol ADCY1 Q08828 O88444 Cyclase Cytosol + Binding 8417150
CALM3 P62158 P62204 Activator Cytosol ADCY1 Q08828 O88444 Cyclase Cytosol + Binding 7685187
CALM3 P62158 P62204 Activator Cytosol ADCY1 Q08828 O88444 Cyclase Cytosol + Binding 2022671
RALBP1 Q15311 Q62172 GAP Cytosol CDC42 P60953 P60766 GTPase Cytosol _ GAP 7623849
ARRB1 P49407 Q8BWG8 Adapter Cytosol F2RL1 P55085 P55086 Receptor Membrane _ Binding 10725339
IGF1R P08069 Q60751 Receptor Cytosol SHC1 P29353 P98083 Adapter Cytosol + Binding 8776723
RALBP1 Q15311 Q62172 GAP Cytosol REPS1 Q96D71 O54916 Adapter Cytosol 0 Binding 9395447
CALCIUM NA NA Messenger Cytosol SRI P30626 Q6P069 Adapter Cytosol + Binding 3028774
PPP3R1 P63098 Q63810 Phosphatase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Dephosphorylation 6330098
MAPK1 P28482 P63085 Kinase Cytosol CREBBP Q92793 P45481 TF Nucleus + Phosphorylation 8941362
DRD3 P35462 P30728 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 15102843
ERBB2 P04626 P70424 Receptor Membrane SHC1 P29353 P98083 Adapter Cytosol + Binding 8026468
FYN P06241 P39688 Kinase Cytosol ITCH Q96J02 Q8C863 E3Ligase Cytosol _ Phosphorylation 16387660
MAP4K1 Q92918 P70218 Kinase Cytosol MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol + Phosphorylation 16195223
CASP6 P55212 O08738 Protease Cytosol LMNA P02545 P48678 Cytoskeleton Nucleus _ Cleavage 11953316
CD38 P28907 P56528 Synthase Cytosol cADPR NA NA Messenger Cytosol + Synthesis 1830494
CD38 P28907 P56528 Synthase Cytosol cADPR NA NA Messenger Cytosol + Synthesis 7692303
GRM1 Q13255 P97772 Receptor Membrane DNM1 Q05193 P39053 GTPase Vesicles 0 Binding 12646135
ARFGEF2 Q9Y6D5 NA GEF Vesicles ARF1 P84077 P84078 GTPase Vesicles + GEF 8945478
ARFGEF2 Q9Y6D5 NA GEF Vesicles ARF1 P84077 P84078 GTPase Vesicles + GEF 8945477
FRAP1 P42345 Q9JLN9 Kinase Cytosol RPS6KB1 P23443 Q8BSK8 Kinase Cytosol + Phosphorylation 11500364
FRAP1 P42345 Q9JLN9 Kinase Cytosol RPS6KB1 P23443 Q8BSK8 Kinase Cytosol + Phosphorylation 12820960
FRAP1 P42345 Q9JLN9 Kinase Cytosol RPS6KB1 P23443 Q8BSK8 Kinase Cytosol + Phosphorylation 12842888
BIRC3 Q13489 O08863 Inhibitor Cytosol CASP7 P55210 P97864 Protease Cytosol _ Binding 9384571
BIRC3 Q13489 O08863 Inhibitor Cytosol CASP3 P42574 P70677 Protease Cytosol _ Binding 9384571
cGMP NA NA Messenger Cytosol PDE3B Q13370 Q61409 PDE Cytosol _ Binding 7870041
cGMP NA NA Messenger Cytosol PDE3A Q14432 Q9Z0X4 PDE Cytosol _ Binding 7870041
RAP1A P62834 P62835 GTPase Cytosol BRAF P15056 P28028 Kinase Cytosol + Binding 9560161
RAP1A P62834 P62835 GTPase Cytosol BRAF P15056 P28028 Kinase Cytosol + Binding 12446733
RAP1A P62834 P62835 GTPase Cytosol BRAF P15056 P28028 Kinase Cytosol + Binding 9094716
GSK3A P49840 NA Kinase Cytosol MAPT P10636 P10637 Activator Cytosol _ Phosphorylation 8228990
GSK3A P49840 NA Kinase Cytosol MAPT P10636 P10637 Activator Cytosol _ Phosphorylation 8799840
GSK3A P49840 NA Kinase Cytosol MAPT P10636 P10637 Activator Cytosol _ Phosphorylation 9689133
GSK3A P49840 NA Kinase Cytosol MAPT P10636 P10637 Activator Cytosol _ Phosphorylation 11007782
cGMP NA NA Messenger Cytosol PDE2A O00408 Q922S4 PDE Cytosol + Binding 7811274
RPS6KB1 P23443 Q8BSK8 Kinase Cytosol FOS P01100 P01101 TF Nucleus + Phosphorylation 8248197
CALCIUM NA NA Messenger Cytosol ACTN3 Q08043 O88990 Cytoskeletal Cytosol _ Binding 9952395
ARHGEF2 Q92974 Q60875 GEF Cytosol RAC1 P63000 P63001 GTPase Cytosol + GEF 9857026
CASP3 P42574 P70677 Protease Cytosol RB1 P06400 P13405 TF Nucleus _ Cleavage 10822366
DLG4 P78352 Q62108 Adapter Cytosol LYN P07948 P25911 Kinase Cytosol 0 Binding 14529711
ARRB1 P49407 Q8BWG8 Adapter Cytosol CLTA P09496 O08585 Vesicle Vesicles 0 Binding 10770944
DRD3 P35462 P30728 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 15102843
CALM3 P62158 P62204 Activator Cytosol PDE1C Q14123 Q64338 PDE Cytosol + Binding 15082510
CALM3 P62158 P62204 Activator Cytosol PDE1B Q01064 Q01065 PDE Cytosol + Binding 3021730
CALM3 P62158 P62204 Activator Cytosol PDE1A P54750 Q61481 PDE Cytosol + Binding 3021730
GRB2 P62993 Q60631 Adapter Cytosol GAB1 Q13480 Q9QYY0 Adapter Cytosol + Binding 8596638
PDE2A O00408 Q922S4 PDE Cytosol CAMP P49913 P51437 Messenger Cytosol _ PDE 7811274
DOK1 Q99704 P97465 Adapter Cytosol NCK1 P16333 NA Adapter Cytosol 0 Binding 10202139
DOK1 Q99704 P97465 Adapter Cytosol NCK1 P16333 NA Adapter Cytosol 0 Binding 9233798
CRK P46108 Q64010 Adapter Cytosol BCAR1 P56945 Q61140 Adapter Cytosol 0 Binding 8070403
CRK P46108 Q64010 Adapter Cytosol BCAR1 P56945 Q61140 Adapter Cytosol 0 Binding 8662907
PTAFR P25105 Q62035 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 1311408
PTAFR P25105 Q62035 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 3013161
PRSS1 P07477 NA Protease Extracellular F2RL1 P55085 P55086 Receptor Membrane + Binding 9349532
RAPGEF1 Q13905 NA GEF Cytosol NRAS P01111 P08556 GTPase Cytosol + GEF 7959692
CDK5 Q00535 P49615 Kinase Cytosol MAPT P10636 P10637 Activator Cytosol + Phosphorylation 8282104
CDK5 Q00535 P49615 Kinase Cytosol MAPT P10636 P10637 Activator Cytosol + Phosphorylation 7592534
AP1B1 Q10567 O35643 Adapter Cytosol CLTA P09496 O08585 Vesicle Vesicles + Binding 11050117
AP1B1 Q10567 O35643 Adapter Cytosol CLTA P09496 O08585 Vesicle Vesicles + Binding 8909539
EGF P01133 P01132 Ligand Extracellular EGFR P00533 Q01279 Receptor Membrane + Binding 11331309
SDCBP O00560 O08992 Adapter Cytosol GRIA1 P42261 P23818 Channel Membrane 0 Binding 11891216
PRKACA P17612 P05132 Kinase Cytosol RIMS1 Q86UR5 Q99NE5 Adapter Vesicles + Phosphorylation 14532002
CALM3 P62158 P62204 Activator Cytosol CAMKK2 Q96RR4 Q8C078 Kinase Cytosol + Binding 10187789
PRKCA P17252 P20444 Kinase Cytosol STXBP1 P61764 O08599 Vesicle Vesicles _ Phosphorylation 10651895
SAPAP NA NA Adapter Cytosol SSCAM NA NA Adapter Cytosol 0 Binding 9694864
EIF4E P06730 P63073 Adapter Ribosomes mRNA NA NA RNA Ribosomes 0 Binding 217002
RIMS1 Q86UR5 Q99NE5 Adapter Vesicles RPH3A Q9Y2J0 P47708 Vesicle Vesicles + Binding 11431472
AKT1 P31749 P31750 Kinase Cytosol GSK3A P49840 NA Kinase Cytosol _ Phosphorylation 8524413
IGF1R P08069 Q60751 Receptor Cytosol GRB10 Q13322 Q60760 Adapter Cytosol + Binding 8776723
CREM Q03060 P27699 TF Nucleus CREB1 P16220 Q01147 TF Nucleus _ Binding 1847666
DNAJC5 Q9H3Z4 P60904 Adapter Cytosol GNB2 P62879 P62880 Gprotein Cytosol + Binding 11086994
CDK5 Q00535 P49615 Kinase Cytosol NEFH P12036 P19246 Cytoskeleton Cytosol + Phosphorylation 7760048
HSPA5 P11021 P20029 Chaperone ER SEC61A1 P61619 P61620 Channel ER + Binding 1568250
CALM3 P62158 P62204 Activator Cytosol DRD2 P14416 P61168 Receptor Membrane _ Binding 10926927
SSTR2 P30874 P30875 Receptor Membrane SH3KBP1 Q96B97 Q8R550 Phosphatase Cytosol + Binding 9305905
RGS2 P41220 O08849 Gprotein Cytosol GNA11 P29992 P21278 Gprotein Cytosol _ GAP 14976183
ADCY2 Q08462 Q80TL1 Cyclase Cytosol CAMP P49913 P51437 Messenger Cytosol + Synthesis 1719547
ERBB2IP Q96RT1 Q80TH2 Adapter Cytosol CTNND2 Q9UQB3 O35927 Adapter Cytosol 0 Binding 11821434
RAF1 P04049 Q99N57 Kinase Cytosol DMPK Q09013 P54265 Kinase Cytosol + Phosphorylation 10869570
TYRO3 Q06418 P55144 Receptor Membrane RANBP9 Q96S59 P69566 Adapter Cytosol + Binding 15964779
CNR1 P21554 P47746 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 2165569
CNR1 P21554 P47746 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 15082510
BCL2L1 Q07817 Q64373 Bcl2Family Mitochondria BIK Q13323 NA Bcl2Family Cytosol _ Binding 9305912
DLG4 P78352 Q62108 Adapter Cytosol DLG2 Q15700 Q91XM9 Adapter Cytosol 0 Binding 8755482
BCL2L1 Q07817 Q64373 Bcl2Family Mitochondria BID P55957 P70444 Bcl2Family Cytosol _ Binding 9873064
CAMK4 Q16566 P08414 Kinase Cytosol CREM Q03060 P27699 TF Nucleus + Phosphorylation 7799965
CAMK4 Q16566 P08414 Kinase Cytosol CREM Q03060 P27699 TF Nucleus + Phosphorylation 8523736
NFASC O94856 Q810U3 CellAdhesion Membrane ANK1 P16157 Q02357 Cytoskeleton Cytosol 0 Binding 7961622
IRS1 P35568 P35569 Adapter Cytosol NCK1 P16333 NA Adapter Cytosol + Binding 8265614
AMPH P49418 Q7TQF7 Adapter Cytosol DNM1 Q05193 P39053 GTPase Vesicles 0 Binding 11877424
AMPH P49418 Q7TQF7 Adapter Cytosol DNM1 Q05193 P39053 GTPase Vesicles 0 Binding 11050117
PRKCA P17252 P20444 Kinase Cytosol GAP43 P17677 P06837 Adapter Cytosol + Phosphorylation 7891109
PRKCA P17252 P20444 Kinase Cytosol GAP43 P17677 P06837 Adapter Cytosol + Phosphorylation 2562806
KCNJ4 P48050 P52189 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 8893032
TCF7 P36402 Q00417 TF Nucleus LEF1 Q9UJU2 P27782 TF Nucleus + Binding 12032083
FHL2 Q14192 O70433 TF Nucleus JUN P05412 P05627 TF Nucleus + Binding 12644711
PPP3R1 P63098 Q63810 Phosphatase Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol + Dephosphorylation 7694293
LCK P06239 P06240 Kinase Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Phosphorylation 7935389
FOSB P53539 P13346 TF Nucleus JUND P17535 P15066 TF Nucleus 0 Binding 1827203
FOSB P53539 P13346 TF Nucleus JUND P17535 P15066 TF Nucleus 0 Binding 12192032
PRKACA P17612 P05132 Kinase Cytosol RCS NA NA Inhibitor Cytosol + Phosphorylation 15499021
FOSB P53539 P13346 TF Nucleus JUNB P17275 P09450 TF Nucleus 0 Binding 1827203
FOSB P53539 P13346 TF Nucleus JUNB P17275 P09450 TF Nucleus 0 Binding 12192032
PTAFR P25105 Q62035 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 8858930
SIPA1 Q96FS4 P46062 GAP Cytosol DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 12059963
GABRA1 P14867 P62812 Receptor Membrane GABARAPL3 Q9BY60 NA Adapter Cytosol 0 Binding 9892355
GABRA1 P14867 P62812 Receptor Membrane GABARAPL3 Q9BY60 NA Adapter Cytosol 0 Binding 10984509
GABRA1 P14867 P62812 Receptor Membrane GABARAPL3 Q9BY60 NA Adapter Cytosol 0 Binding 11414770
ACTB P60709 P60710 Cytoskeleton Cytosol MARCKS P29966 P26645 Adapter Cytosol 0 Binding 1560845
GLYCINE NA NA Ligand Extracellular GRIN2A Q12879 P35436 Receptor Membrane + Binding 7870047
GLYCINE NA NA Ligand Extracellular GRIN2A Q12879 P35436 Receptor Membrane + Binding 12646920
GLYCINE NA NA Ligand Extracellular GRIN2A Q12879 P35436 Receptor Membrane + Binding 2433595
GLYCINE NA NA Ligand Extracellular GRIN2A Q12879 P35436 Receptor Membrane + Binding 8768735
GRB2 P62993 Q60631 Adapter Cytosol VAV1 P15498 P27870 GEF Cytosol + Binding 7809090
CTNNB1 P35222 Q02248 TF Cytosol TCF7 P36402 Q00417 TF Nucleus + Binding 9065401
CRK P46108 Q64010 Adapter Cytosol CHN1 P15882 Q91V57 GAP Cytosol + Binding 12446789
DYNLL1 P63167 P63168 Adapter Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol 0 Binding 10679011
CAMK2A Q9UQM7 P11798 Kinase Cytosol MAP3K5 Q99683 O35099 Kinase Cytosol + Phosphorylation 14749717
MPDZ O75970 Q8VBX6 Adapter Cytosol SYNGAP1 Q96PV0 NA GEF Cytosol _ Binding 15312654
PPP1CC P36873 P63087 Phosphatase Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Dephosphorylation 8183343
SH3GL2 Q99962 Q62420 Vesicle Vesicles DNM1 Q05193 P39053 GTPase Vesicles 0 Binding 11877424
SH3GL2 Q99962 Q62420 Vesicle Vesicles DNM1 Q05193 P39053 GTPase Vesicles 0 Binding 10490020
FER P16591 NA Kinase Cytosol CTNNB1 P35222 Q02248 TF Cytosol + Phosphorylation 12640114
PRKACA P17612 P05132 Kinase Cytosol DRD1 P21728 Q61616 Receptor Membrane _ Phosphorylation 7609904
PIP3 NA NA Lipid Cytosol PRKCA P17252 P20444 Kinase Cytosol + Binding 8395820
ARHGEF7 Q14155 Q9ES28 GEF Cytosol RAC1 P63000 P63001 GTPase Cytosol + GEF 9659915
PA NA NA Messenger Cytosol PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol + Binding 12578375
MAP3K3 Q99759 Q61084 Kinase Cytosol MAP4K3 Q8IVH8 Q99JP0 Kinase Cytosol + Phosphorylation 9162092
BCL2L1 Q07817 Q64373 Bcl2Family Mitochondria BAX Q07812 Q07813 Bcl2Family Mitochondria _ Binding 8596636
CALCIUM NA NA Messenger Cytosol DOC2A Q14183 Q7TNF0 Vesicle Vesicles + Binding 9195900
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol SERPINB2 P05120 P12388 Inhibitor Cytosol + Phosphorylation 6090457
PRKACA P17612 P05132 Kinase Cytosol ATP2B1 P20020 NA Pump Membrane _ Phosphorylation 9824678
PTPN1 P18031 P35821 Phosphatase Cytosol INSR P06213 P15208 Receptor Membrane _ Dephosphorylation 14722096
S60 NA NA Ribosome Ribosomes SRP54 P61011 P14576 Adapter Ribosomes + GEF 12913112
HAPIP O60229 NA GEF Cytosol RAC1 P63000 P63001 GTPase Cytosol + GEF 12546821
JUN P05412 P05627 TF Nucleus CREBBP Q92793 P45481 TF Nucleus + Binding 9407028
CAMP P49913 P51437 Messenger Cytosol RAPGEF4 Q8WZA2 Q9EQZ6 GEF Cytosol + Binding 11056535
CAMP P49913 P51437 Messenger Cytosol RAPGEF4 Q8WZA2 Q9EQZ6 GEF Cytosol + Binding 9856955
CAMP P49913 P51437 Messenger Cytosol RAPGEF3 O95398 Q8VCC8 GEF Cytosol + Binding 12888551
CAMP P49913 P51437 Messenger Cytosol RAPGEF3 O95398 Q8VCC8 GEF Cytosol + Binding 9853756
SRC P12931 P05480 Kinase Cytosol GNB2L1 P63244 P68040 Adapter Cytosol 0 Binding 11279199
CARD14 Q9BXL6 Q99KF0 Kinase Cytosol EIF4E P06730 P63073 Adapter Ribosomes + Phosphorylation 9155017
CARD14 Q9BXL6 Q99KF0 Kinase Cytosol EIF4E P06730 P63073 Adapter Ribosomes + Phosphorylation 10022874
BID P55957 P70444 Bcl2Family Cytosol BAX Q07812 Q07813 Bcl2Family Mitochondria + Binding 8918887
GRIN2A Q12879 P35436 Receptor Membrane RASGRF1 Q13972 P27671 GEF Cytosol 0 Binding 14622581
ADRA1A P35348 P97718 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 1334487
ADRA1A P35348 P97718 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 1334487
MAPK1 P28482 P63085 Kinase Cytosol ELK1 P19419 P41969 TF Nucleus + Phosphorylation 8477450
MAPK1 P28482 P63085 Kinase Cytosol ELK1 P19419 P41969 TF Nucleus + Phosphorylation 9501095
LIMK1 P53667 P53668 Kinase Cytosol CFL1 P23528 P18760 Cytoskeleton Cytosol _ Phosphorylation 9655398
LIMK1 P53667 P53668 Kinase Cytosol CFL1 P23528 P18760 Cytoskeleton Cytosol _ Phosphorylation 12361576
LIMK1 P53667 P53668 Kinase Cytosol CFL1 P23528 P18760 Cytoskeleton Cytosol _ Phosphorylation 10436159
PPP1R1B Q9UD71 Q60829 Inhibitor Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol _ Binding 9108011
PPP1R1B Q9UD71 Q60829 Inhibitor Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol _ Binding 6087160
AXIN1 O15169 O35625 Adapter Cytosol ANAPC1 Q9H1A4 P53995 Adapter Cytosol 0 Binding 9734785
AXIN1 O15169 O35625 Adapter Cytosol ANAPC1 Q9H1A4 P53995 Adapter Cytosol 0 Binding 9556553
AXIN1 O15169 O35625 Adapter Cytosol ANAPC1 Q9H1A4 P53995 Adapter Cytosol 0 Binding 9601641
CNKSR1 Q969H4 NA Kinase Cytosol MAP4K1 Q92918 P70218 Kinase Cytosol 0 Binding 10891492
MAP3K2 Q9Y2U5 Q61083 Kinase Cytosol MAP2K4 P45985 P47809 Kinase Cytosol + Phosphorylation 9162092
KCND1 Q9NSA2 Q03719 Channel Membrane DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 11723117
GDF15 Q99988 Q9Z0J7 Ligand Extracellular ERBB2 P04626 P70424 Receptor Membrane + Binding 6328316
PPP3R1 P63098 Q63810 Phosphatase Cytosol CREB1 P16220 Q01147 TF Nucleus _ Dephosphorylation 14697672
PPP3R1 P63098 Q63810 Phosphatase Cytosol CREB1 P16220 Q01147 TF Nucleus _ Dephosphorylation 8195196
EIF4EBP3 O60516 Q80VV3 TF Nucleus EIF4E P06730 P63073 Adapter Ribosomes _ Binding 9472019
EIF4EBP3 O60516 Q80VV3 TF Nucleus EIF4E P06730 P63073 Adapter Ribosomes _ Binding 7935836
PTPN11 Q06124 P35235 Phosphatase Cytosol PXN P49023 Q8VI36 Adapter Cytosol _ Dephosphorylation 14665621
MAP3K1 Q13233 P53349 Kinase Cytosol CHUK O15111 Q60680 Kinase Cytosol + Phosphorylation 9689078
GRIN2A Q12879 P35436 Receptor Membrane CAMK2A Q9UQM7 P11798 Kinase Cytosol 0 Binding 12379661
GRIN2A Q12879 P35436 Receptor Membrane CAMK2A Q9UQM7 P11798 Kinase Cytosol 0 Binding 10077668
CREB1 P16220 Q01147 TF Nucleus GTF2B Q00403 P62915 TF Nucleus + Binding 7615553
BDKRB1 P46663 Q61125 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 1645526
BDKRB1 P46663 Q61125 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 11713280
BDKRB1 P46663 Q61125 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 11713280
BDKRB1 P46663 Q61125 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 11379050
MAP3K2 Q9Y2U5 Q61083 Kinase Cytosol PROK2 Q9HC23 Q9QXU7 Kinase Cytosol + Binding 10818102
SF1 Q15637 Q64213 Adapter Cytosol CREBBP Q92793 P45481 TF Nucleus _ Binding 12496368
ABL1 P00519 P00520 Kinase Cytosol CDK5 Q00535 P49615 Kinase Cytosol + Phosphorylation 11113134
CALM3 P62158 P62204 Activator Cytosol AKAP5 P24588 NA Adapter Cytosol _ Binding 9202019
RGS4 P49798 O08899 GAP Cytosol GNAQ P50148 P21279 Gprotein Cytosol _ GAP 9012799
ACTN3 Q08043 O88990 Cytoskeletal Cytosol RPH3A Q9Y2J0 P47708 Vesicle Vesicles 0 Binding 8943213
EPN1 Q9Y6I3 Q80VP1 Adapter Vesicles ITSN1 Q15811 Q9Z0R4 Adapter Vesicles 0 Binding 10336464
EPN1 Q9Y6I3 Q80VP1 Adapter Vesicles ITSN1 Q15811 Q9Z0R4 Adapter Vesicles 0 Binding 9813051
PPP3R1 P63098 Q63810 Phosphatase Cytosol ITPR1 Q14643 P11881 Channel ER + Dephosphorylation 8521476
S40 NA NA Ribosome Ribosomes mRNA NA NA RNA Ribosomes 0 Binding 5341323
S40 NA NA Ribosome Ribosomes mRNA NA NA RNA Ribosomes 0 Binding 4909872
DMPK Q09013 P54265 Kinase Cytosol PPP1R12B O60237 Q8BG95 Phosphatase Cytosol _ Phosphorylation 11287000
DMPK Q09013 P54265 Kinase Cytosol PPP1R12A O14974 Q9DBR7 Phosphatase Cytosol _ Phosphorylation 11287000
BIRC1 Q13075 NA Inhibitor Cytosol CASP9 P55211 NA Protease Cytosol _ Binding 15280366
BIRC1 Q13075 NA Inhibitor Cytosol CASP7 P55210 P97864 Protease Cytosol _ Binding 11896143
BIRC1 Q13075 NA Inhibitor Cytosol CASP3 P42574 P70677 Protease Cytosol _ Binding 11896143
FOSL2 P15408 P47930 TF Nucleus JUND P17535 P15066 TF Nucleus 0 Binding 1827203
FOSL2 P15408 P47930 TF Nucleus JUND P17535 P15066 TF Nucleus 0 Binding 12192032
FOSL2 P15408 P47930 TF Nucleus JUNB P17275 P09450 TF Nucleus 0 Binding 1827203
FOSL2 P15408 P47930 TF Nucleus JUNB P17275 P09450 TF Nucleus 0 Binding 12192032
RPS6KA1 Q15418 P18653 Kinase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria _ Phosphorylation 10976111
RPS6KA1 Q15418 P18653 Kinase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria _ Phosphorylation 10558990
OPRD1 P41143 P32300 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 15082510
ABL1 P00519 P00520 Kinase Cytosol VAV1 P15498 P27870 GEF Cytosol + Phosphorylation 11790798
GPHN Q9NQX3 NA Adapter Membrane GLRA1 P23415 Q64018 Receptor Membrane 0 Binding 14976213
MAPK1 P28482 P63085 Kinase Cytosol KCND2 Q9NZV8 Q9Z0V2 Channel Membrane + Phosphorylation 12077183
MAPK1 P28482 P63085 Kinase Cytosol KCND2 Q9NZV8 Q9Z0V2 Channel Membrane + Phosphorylation 11080179
GABA NA NA Ligand Extracellular GABBR1 Q9UBS5 Q9WV18 Receptor Membrane _ Binding 9069281
CNR1 P21554 P47746 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 15082510
GZMB P10144 P04187 GEF Cytosol RAB3A P20336 P63011 GTPase Vesicles + GEF 11516400
RALGDS Q12967 Q03385 GEF Cytosol RALA P11233 P63321 GTPase Cytosol + GEF 8094051
PRKG2 Q13237 Q61410 Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 10575022
ACTN3 Q08043 O88990 Cytoskeletal Cytosol ITGB1 P05556 P09055 CellAdhesion Membrane 0 Binding 2116421
DRD1 P21728 Q61616 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 1832710
CALM3 P62158 P62204 Activator Cytosol NRAS P01111 P08556 GTPase Cytosol _ Binding 11585916
STX3 Q13277 Q64704 Vesicle Vesicles SNAP25 P60880 P60879 Vesicle Vesicles 0 Binding 7957071
DLGAP1 O14490 Q9D415 Adapter Cytosol DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 9286856
DOK1 Q99704 P97465 Adapter Cytosol RASGRP3 Q8IV61 NA GAP Cytosol + Binding 9233798
DOK1 Q99704 P97465 Adapter Cytosol RASGRP3 Q8IV61 NA GAP Cytosol + Binding 9008161
STXBP6 Q8NFX7 Q8R3T5 Vesicle Vesicles SNAP25 P60880 P60879 Vesicle Vesicles _ Binding 12145319
DLG4 P78352 Q62108 Adapter Cytosol SYNGAP1 Q96PV0 NA GEF Cytosol 0 Binding 9581761
DLG4 P78352 Q62108 Adapter Cytosol SYNGAP1 Q96PV0 NA GEF Cytosol 0 Binding 9620694
DMPK Q09013 P54265 Kinase Cytosol PLN P26678 P61014 Pump ER + Phosphorylation 15598648
PRKCA P17252 P20444 Kinase Cytosol ADCY5 O95622 P84309 Cyclase Membrane + Phosphorylation 8206971
PRKCA P17252 P20444 Kinase Cytosol ADCY2 Q08462 Q80TL1 Cyclase Cytosol + Phosphorylation 8383119
PRKCA P17252 P20444 Kinase Cytosol ADCY2 Q08462 Q80TL1 Cyclase Cytosol + Phosphorylation 9268695
PRKCA P17252 P20444 Kinase Cytosol ADCY2 Q08462 Q80TL1 Cyclase Cytosol + Phosphorylation 9366262
PRKCA P17252 P20444 Kinase Cytosol ADCY2 Q08462 Q80TL1 Cyclase Cytosol + Phosphorylation 7938004
PRKCA P17252 P20444 Kinase Cytosol ADCY2 Q08462 Q80TL1 Cyclase Cytosol + Phosphorylation 8900209
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol ATP2B1 P20020 NA Pump Membrane + Binding 12511555
GRIN2A Q12879 P35436 Receptor Membrane AKAP9 Q99996 NA Adapter Cytosol 0 Binding 9482789
BCL2 P10415 P10417 Bcl2Family Mitochondria BIK Q13323 NA Bcl2Family Cytosol _ Binding 9305912
BCL2 P10415 P10417 Bcl2Family Mitochondria BID P55957 P70444 Bcl2Family Cytosol _ Binding 8918887
CAPN1 P07384 O35350 Protease Cytosol CABIN1 Q9Y6J0 NA Inhibitor Cytosol _ Cleavage 12114545
CAMK2A Q9UQM7 P11798 Kinase Cytosol SYT1 P21579 P46096 Vesicle Vesicles + Phosphorylation 9016342
CALM3 P62158 P62204 Activator Cytosol CAMK2A Q9UQM7 P11798 Kinase Cytosol + Binding 3006921
ITGB1 P05556 P09055 CellAdhesion Membrane GNB2L1 P63244 P68040 Adapter Cytosol 0 Binding 9442085
RPS6KA1 Q15418 P18653 Kinase Cytosol S6 NA NA Adapter Ribosomes + Phosphorylation 2138782
PPP2R5C Q13362 Q60996 Phosphatase Cytosol CAMK4 Q16566 P08414 Kinase Cytosol _ Dephosphorylation 9596578
PPP2R5C Q13362 Q60996 Phosphatase Cytosol CAMK4 Q16566 P08414 Kinase Cytosol _ Dephosphorylation 15143065
PPP2R5C Q13362 Q60996 Phosphatase Cytosol CAMK1 Q14012 Q91YS8 Kinase Cytosol _ Dephosphorylation 1320022
MAP3K14 Q99558 Q9WUL6 Kinase Cytosol IKBKB O14920 O88351 Kinase Cytosol + Phosphorylation 9244310
MAP3K14 Q99558 Q9WUL6 Kinase Cytosol IKBKB O14920 O88351 Kinase Cytosol + Phosphorylation 9346485
GRB2 P62993 Q60631 Adapter Cytosol TOM1L1 O75674 Q923U0 Adapter Cytosol + Binding 11711534
CNR1 P21554 P47746 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 15082510
PIP2 NA NA Lipid Cytosol KCNJ3 P48549 P63250 Channel Membrane + Binding 10559906
TCF7 P36402 Q00417 TF Nucleus SRF P11831 NA TF Nucleus + Binding 2108863
TCF7 P36402 Q00417 TF Nucleus SRE NA NA DNA Nucleus 0 Binding 2492906
TCF7 P36402 Q00417 TF Nucleus SRE NA NA DNA Nucleus 0 Binding 2108863
HTR2A P28223 P35363 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 6483122
HTR2A P28223 P35363 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 6483122
MAP3K1 Q13233 P53349 Kinase Cytosol EPHA4 P54764 Q03137 Kinase Cytosol + Phosphorylation 7997270
CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol STX3 Q13277 Q64704 Vesicle Vesicles + Phosphorylation 11846792
MAPT P10636 P10637 Activator Cytosol TUBA3 Q71U36 NA Cytoskeleton Cytosol 0 Binding 1421571
AKT1 P31749 P31750 Kinase Cytosol CASP9 P55211 NA Protease Cytosol _ Phosphorylation 9812896
CTNND2 Q9UQB3 O35927 Adapter Cytosol PSEN1 P49768 P49769 Protease Membrane 0 Binding 9223106
PRKCA P17252 P20444 Kinase Cytosol GABRA1 P14867 P62812 Receptor Membrane _ Phosphorylation 11517239
FRAP1 P42345 Q9JLN9 Kinase Cytosol EIF4EBP3 O60516 Q80VV3 TF Nucleus _ Phosphorylation 12820960
FRAP1 P42345 Q9JLN9 Kinase Cytosol EIF4EBP1 Q13541 Q60876 Inhibitor Ribosomes _ Phosphorylation 8895571
SF1 Q15637 Q64213 Adapter Cytosol PLCG1 P19174 Q62077 Phospholipase Cytosol 0 Binding 14647465
PTAFR P25105 Q62035 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 1311408
PTAFR P25105 Q62035 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 8858930
PTAFR P25105 Q62035 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 7797472
PTAFR P25105 Q62035 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 8576109
PLCB1 Q9NQ66 Q9Z1B3 Phospholipase Cytosol PIP2 NA NA Messenger Cytosol _ Cleavage 11941371
NE NA NA Ligand Extracellular ADRA2A P08913 Q01338 Receptor Membrane + Binding 9733758
NE NA NA Ligand Extracellular ADRA2A P08913 Q01338 Receptor Membrane + Binding 3016604
DRD1 P21728 Q61616 Receptor Membrane GNAS P63092 P63094 Gprotein Cytosol + Binding 1832710
DRD1 P21728 Q61616 Receptor Membrane GNAS P63092 P63094 Gprotein Cytosol + Binding 2898118
DRD1 P21728 Q61616 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 1832710
MAP4K3 Q8IVH8 Q99JP0 Kinase Cytosol MAPK14 Q16539 P47811 Kinase Cytosol + Phosphorylation 8622669
CHRM2 P08172 Q9ERZ4 Receptor Membrane RGS2 P41220 O08849 Gprotein Cytosol 0 Binding 9736641
EPN1 Q9Y6I3 Q80VP1 Adapter Vesicles CLTA P09496 O08585 Vesicle Vesicles 0 Binding 10336464
NE NA NA Ligand Extracellular ADRA1A P35348 P97718 Receptor Membrane + Binding 9733758
NE NA NA Ligand Extracellular ADRA1A P35348 P97718 Receptor Membrane + Binding 3016604
CAMK2A Q9UQM7 P11798 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Phosphorylation 7890745
CAMK2A Q9UQM7 P11798 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Phosphorylation 9016342
CAMK2A Q9UQM7 P11798 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Phosphorylation 3118371
CAMK2A Q9UQM7 P11798 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Phosphorylation 7849051
STON2 Q8WXE9 Q8BZ60 Adapter Vesicles SYT1 P21579 P46096 Vesicle Vesicles 0 Binding 11381094
BDNF P23560 P21237 Ligand Extracellular NGFR P08138 Q9Z0W1 Receptor Membrane + Binding 15883381
CREBBP Q92793 P45481 TF Nucleus JUN P05412 P05627 TF Nucleus + Binding 8545107
STAT1 P42224 P42225 TF Nucleus CREBBP Q92793 P45481 TF Nucleus 0 Binding 9037008
STAT1 P42224 P42225 TF Nucleus CREBBP Q92793 P45481 TF Nucleus 0 Binding 9773981
PIN1 Q13526 Q9QUR7 TF Nucleus JUN P05412 P05627 TF Nucleus + Binding 16123044
PIN1 Q13526 Q9QUR7 TF Nucleus JUN P05412 P05627 TF Nucleus + Binding 11432833
DAPK1 P53355 Q80YE7 Kinase Cytosol STX3 Q13277 Q64704 Vesicle Vesicles _ Phosphorylation 12730201
BCL2 P10415 P10417 Bcl2Family Mitochondria BAX Q07812 Q07813 Bcl2Family Mitochondria _ Binding 8358790
GSK3A P49840 NA Kinase Cytosol SERPINB2 P05120 P12388 Inhibitor Cytosol + Phosphorylation 6090457
GSK3A P49840 NA Kinase Cytosol SERPINB2 P05120 P12388 Inhibitor Cytosol + Phosphorylation 6091765
GSK3A P49840 NA Kinase Cytosol MITF O75030 Q08874 TF Nucleus + Phosphorylation 10587587
YWHAH Q04917 P68510 Adapter Cytosol BRAF P15056 P28028 Kinase Cytosol + Binding 7744815
YWHAH Q04917 P68510 Adapter Cytosol BRAF P15056 P28028 Kinase Cytosol + Binding 8085159
YWHAH Q04917 P68510 Adapter Cytosol BRAF P15056 P28028 Kinase Cytosol + Binding 8085158
YWHAH Q04917 P68510 Adapter Cytosol BRAF P15056 P28028 Kinase Cytosol + Binding 10931830
ELK1 P19419 P41969 TF Nucleus TCF7 P36402 Q00417 TF Nucleus 0 Binding 1722028
NFKBIA P25963 Q9Z1E3 Inhibitor Cytosol NFKB1 P19838 P25799 TF Nucleus _ Binding 2184941
PAK1 Q13153 O88643 Kinase Cytosol SYN1 P17600 O88935 Vesicle Vesicles _ Phosphorylation 14557263
FOSL1 P15407 P48755 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 1827203
FOSL1 P15407 P48755 TF Nucleus JUN P05412 P05627 TF Nucleus 0 Binding 12192032
PADI1 Q9ULC6 Q9Z185 Chaperone ER NASCENTCHAIN NA NA Peptide Ribosomes + Binding 812800
PPP1R1A Q13522 Q9ERT9 Inhibitor Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol _ Binding 8611507
PPP1R1A Q13522 Q9ERT9 Inhibitor Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol _ Binding 9765309
CAMK2A Q9UQM7 P11798 Kinase Cytosol CACNA1B Q00975 O55017 Channel Membrane + Phosphorylation 9278528
SRC P12931 P05480 Kinase Cytosol VAV1 P15498 P27870 GEF Cytosol + Phosphorylation 1311423
SRC P12931 P05480 Kinase Cytosol VAV1 P15498 P27870 GEF Cytosol + Phosphorylation 1531699
CPLX1 O14810 P63040 Vesicle Vesicles SNAP25 P60880 P60879 Vesicle Vesicles 0 Binding 7553862
PRKCA P17252 P20444 Kinase Cytosol TIAM1 Q13009 Q60610 GEF Cytosol 0 Phosphorylation 10212259
PRKCA P17252 P20444 Kinase Cytosol TIAM1 Q13009 Q60610 GEF Cytosol 0 Phosphorylation 9407095
PTK2 Q05397 P34152 Kinase Cytosol ACTN3 Q08043 O88990 Cytoskeletal Cytosol _ Phosphorylation 11369769
PTK2 Q05397 P34152 Kinase Cytosol ACTN3 Q08043 O88990 Cytoskeletal Cytosol _ Phosphorylation 15070900
MAP2K7 O14733 NA Kinase Cytosol MAPK8 P45983 Q91Y86 Kinase Nucleus + Phosphorylation 9733513
NTRK1 P04629 NA Receptor Membrane IRS1 P35568 P35569 Adapter Cytosol + Phosphorylation 11147812
PRKACA P17612 P05132 Kinase Cytosol PDE5A O76074 Q8CG03 PDE Cytosol + Phosphorylation 15082510
CACNA1E Q15878 Q61290 Channel Membrane CALCIUM NA NA Messenger Cytosol + Opening 8071363
ATF2 P15336 P16951 TF Nucleus CRE NA NA DNA Nucleus + Binding 2320002
FGA P02671 NA Ligand Extracellular ITGB1 P05556 P09055 CellAdhesion Membrane + Binding 7716514
PRKACA P17612 P05132 Kinase Cytosol PDE4D Q08499 Q01063 PDE Cytosol + Phosphorylation 15082510
CERAMIDE NA NA Lipid Cytosol PPP2R5C Q13362 Q60996 Phosphatase Cytosol + Binding 10400653
CERAMIDE NA NA Lipid Cytosol PPP2R5C Q13362 Q60996 Phosphatase Cytosol + Binding 8393446
RASGRP3 Q8IV61 NA GAP Cytosol AKT1 P31749 P31750 Kinase Cytosol + Binding 14707121
CACNG7 P62955 P62956 Chaperone Cytosol DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 12359873
ADORA2A P29274 Q60613 Receptor Membrane GNAS P63092 P63094 Gprotein Cytosol + Binding 8995267
ADORA2A P29274 Q60613 Receptor Membrane GNAS P63092 P63094 Gprotein Cytosol + Binding 6162091
ADORA2A P29274 Q60613 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 8995267
PRKACA P17612 P05132 Kinase Cytosol PDE3B Q13370 Q61409 PDE Cytosol + Phosphorylation 2839485
PRKACA P17612 P05132 Kinase Cytosol PDE3A Q14432 Q9Z0X4 PDE Cytosol + Phosphorylation 2839485
CALM3 P62158 P62204 Activator Cytosol VAPA Q9P0L0 Q9WV55 Vesicle Vesicles _ Binding 10944231
ERBB2 P04626 P70424 Receptor Membrane SNTA1 Q13424 Q61234 Adapter Cytosol + Binding 10725395
EIF4EBP1 Q13541 Q60876 Inhibitor Ribosomes EIF4E P06730 P63073 Adapter Ribosomes _ Binding 7935836
CASP3 P42574 P70677 Protease Cytosol GSN P06396 P13020 Cytoskeleton Cytosol _ Cleavage 9323209
BCAP31 P51572 Q61335 Adapter ER BCL2 P10415 P10417 Bcl2Family Mitochondria + Binding 9334338
PDPK1 O15530 Q9Z2A0 Kinase Cytosol RPS6KB1 P23443 Q8BSK8 Kinase Cytosol + Phosphorylation 9427642
ACTB P60709 P60710 Cytoskeleton Cytosol NFASC O94856 Q810U3 CellAdhesion Membrane 0 Binding 8999969
CDC42 P60953 P60766 GTPase Cytosol WASF1 Q92558 Q8R5H6 Activator Cytosol + Binding 11052943
CDC42 P60953 P60766 GTPase Cytosol WASF1 Q92558 Q8R5H6 Activator Cytosol + Binding 8643625
CDC42 P60953 P60766 GTPase Cytosol WASF1 Q92558 Q8R5H6 Activator Cytosol + Binding 10360578
CREBBP Q92793 P45481 TF Nucleus SRF P11831 NA TF Nucleus 0 Binding 9388250
PRKCA P17252 P20444 Kinase Cytosol BCL2 P10415 P10417 Bcl2Family Mitochondria _ Phosphorylation 9738012
CTTN Q14247 Q60598 Cytoskeleton Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol + Binding 11018051
CTTN Q14247 Q60598 Cytoskeleton Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol + Binding 7680654
NGFR P08138 Q9Z0W1 Receptor Membrane RANBP9 Q96S59 P69566 Adapter Cytosol + Binding 12963025
PDPK1 O15530 Q9Z2A0 Kinase Cytosol RPS6KA1 Q15418 P18653 Kinase Cytosol + Phosphorylation 10480933
CASP3 P42574 P70677 Protease Cytosol PPP2R5C Q13362 Q60996 Phosphatase Cytosol _ Cleavage 9582351
PKN1 Q16512 P70268 Kinase Cytosol PPP1R14A Q96A00 Q91VC7 Inhibitor Cytosol + Phosphorylation 10924361
BIRC5 O15392 O70201 Adapter Cytosol DIABLO Q9NR28 Q9JIQ3 Inhibitor Mitochondria _ Binding 12660240
PPP3R1 P63098 Q63810 Phosphatase Cytosol MAPT P10636 P10637 Activator Cytosol _ Dephosphorylation 2987415
PPP3R1 P63098 Q63810 Phosphatase Cytosol MAPT P10636 P10637 Activator Cytosol _ Dephosphorylation 12064514
PPP3R1 P63098 Q63810 Phosphatase Cytosol MAPT P10636 P10637 Activator Cytosol _ Dephosphorylation 8720139
ARHGAP1 Q07960 NA GTPase Cytosol CIT O14578 P49025 Kinase Cytosol + Binding 9697773
PRKACA P17612 P05132 Kinase Cytosol GRIN2A Q12879 P35436 Receptor Membrane + Phosphorylation 9115280
PDE4D Q08499 Q01063 PDE Cytosol CAMP P49913 P51437 Messenger Cytosol _ PDE 9371713
CAMK2A Q9UQM7 P11798 Kinase Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol _ Phosphorylation 10874031
CAMK2A Q9UQM7 P11798 Kinase Cytosol NOS1 P29475 Q9Z0J4 Synthase Cytosol _ Phosphorylation 10400690
PPP3R1 P63098 Q63810 Phosphatase Cytosol MAP2 P11137 P20357 Cytoskeleton Cytosol _ Dephosphorylation 8393539
PPP3R1 P63098 Q63810 Phosphatase Cytosol MAP2 P11137 P20357 Cytoskeleton Cytosol _ Dephosphorylation 2987415
HOMER2 Q9NSB8 Q9QWW1 Adapter Cytosol DNM1 Q05193 P39053 GTPase Vesicles 0 Binding 12646135
MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol ARHGEF1 Q92888 Q61210 GEF Cytosol 0 Binding 10574993
ARHGEF12 Q9NZN5 Q8R4H2 GEF Cytosol ARHGAP1 Q07960 NA GTPase Cytosol + GEF 11373293
ABL1 P00519 P00520 Kinase Cytosol SHC1 P29353 P98083 Adapter Cytosol 0 Binding 8112292
REPS1 Q96D71 O54916 Adapter Cytosol GRB2 P62993 Q60631 Adapter Cytosol 0 Binding 9395447
GAP43 P17677 P06837 Adapter Cytosol CALM3 P62158 P62204 Activator Cytosol _ Binding 1824695
HSP90B1 P14625 P08113 Chaperone ER NASCENTCHAIN NA NA Peptide Ribosomes 0 Binding 1400441
HSP90B1 P14625 P08113 Chaperone ER NASCENTCHAIN NA NA Peptide Ribosomes 0 Binding 2944601
SIAH2 O43255 Q06986 Adapter Cytosol VAV1 P15498 P27870 GEF Cytosol _ Binding 10207103
KCNJ3 P48549 P63250 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 8355805
FYN P06241 P39688 Kinase Cytosol CACNA1C Q13936 Q01815 Channel Membrane + Phosphorylation 12850569
KCNIP3 Q9Y2W7 P0C092 TF Nucleus CREB1 P16220 Q01147 TF Nucleus _ Binding 12198160
HTR1A P08908 Q64264 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 1589591
STON2 Q8WXE9 Q8BZ60 Adapter Vesicles AP2S1 P53680 P62743 Adapter Vesicles 0 Binding 11381094
EIF2AK3 Q9NZJ5 Q9Z2B5 Kinase Cytosol EIF2S1 P05198 Q6ZWX6 Ribosome Ribosomes + Phosphorylation 9930704
YWHAH Q04917 P68510 Adapter Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria _ Binding 16009721
YWHAH Q04917 P68510 Adapter Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria _ Binding 8929531
MAPK1 P28482 P63085 Kinase Cytosol CARD14 Q9BXL6 Q99KF0 Kinase Cytosol + Phosphorylation 9155018
MAPK1 P28482 P63085 Kinase Cytosol CARD14 Q9BXL6 Q99KF0 Kinase Cytosol + Phosphorylation 9155017
PRKCA P17252 P20444 Kinase Cytosol PTPN11 Q06124 P35235 Phosphatase Cytosol + Phosphorylation 16055440
PABPC1 P11940 P29341 Ribosome Ribosomes mRNA NA NA RNA Ribosomes 0 Binding 3537727
GRM1 Q13255 P97772 Receptor Membrane GNA11 P29992 P21278 Gprotein Cytosol + Binding 12351712
MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol MAP2K7 O14733 NA Kinase Cytosol + Binding 9733513
CAMK2A Q9UQM7 P11798 Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 1646483
CAMK2A Q9UQM7 P11798 Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 7958915
MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol MAP2K4 P45985 P47809 Kinase Cytosol + Binding 9733513
GLUTAMATE NA NA Ligand Extracellular GRIK1 P39086 Q60934 Channel Membrane + Binding 1373382
MYRIP Q8NFW9 Q8K3I4 Cytoskeleton Cytosol CAMK2A Q9UQM7 P11798 Kinase Cytosol + Binding 10336484
AKAP5 P24588 NA Adapter Cytosol DLG4 P78352 Q62108 Adapter Cytosol 0 Binding 10939335
TSC2 P49815 Q61037 GAP Cytosol RAP1A P62834 P62835 GTPase Cytosol _ GAP 7608212
GRIA1 P42261 P23818 Channel Membrane SODIUM NA NA Ion Cytosol + Opening 1380467
GRIA1 P42261 P23818 Channel Membrane SODIUM NA NA Ion Cytosol + Opening 1652753
GRIA1 P42261 P23818 Channel Membrane SODIUM NA NA Ion Cytosol + Opening 8589990
MAP3K5 Q99683 O35099 Kinase Cytosol MAP4K3 Q8IVH8 Q99JP0 Kinase Cytosol + Phosphorylation 8974401
DLG1 Q12959 Q811D0 Adapter Cytosol GRIK1 P39086 Q60934 Channel Membrane _ Binding 9808460
PRKCA P17252 P20444 Kinase Cytosol AKAP5 P24588 NA Adapter Cytosol 0 Binding 8599116
PRKCA P17252 P20444 Kinase Cytosol AKAP5 P24588 NA Adapter Cytosol 0 Binding 12359152
HTR4 Q13639 P97288 Receptor Membrane GNAS P63092 P63094 Gprotein Cytosol + Binding 2314390
HTR4 Q13639 P97288 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 2314390
PIN1 Q13526 Q9QUR7 TF Nucleus TP53BP1 Q12888 P70399 TF Nucleus + Binding 16123044
GSK3A P49840 NA Kinase Cytosol CTNNB1 P35222 Q02248 TF Cytosol _ Phosphorylation 9482734
GSK3A P49840 NA Kinase Cytosol CTNNB1 P35222 Q02248 TF Cytosol _ Phosphorylation 9601641
BRAF P15056 P28028 Kinase Cytosol MAP4K1 Q92918 P70218 Kinase Cytosol + Phosphorylation 7731720
BRAF P15056 P28028 Kinase Cytosol MAP4K1 Q92918 P70218 Kinase Cytosol + Phosphorylation 8073291
BRAF P15056 P28028 Kinase Cytosol MAP4K1 Q92918 P70218 Kinase Cytosol + Phosphorylation 1748651
BRAF P15056 P28028 Kinase Cytosol MAP4K1 Q92918 P70218 Kinase Cytosol + Phosphorylation 3043188
BRAF P15056 P28028 Kinase Cytosol MAP4K1 Q92918 P70218 Kinase Cytosol + Phosphorylation 8385802
CASKIN1 Q8WXD9 Q6P9K8 Vesicle Vesicles CSNK1G1 Q9HCP0 Q8BTH8 Kinase Cytosol 0 Binding 12040031
CALCIUM NA NA Messenger Cytosol RASGRP3 Q8IV61 NA GAP Cytosol + Binding 9582122
DLG4 P78352 Q62108 Adapter Cytosol NLGN1 Q8N2Q7 Q99K10 CellAdhesion Membrane 0 Binding 9278515
RYR1 P21817 NA Channel ER CALCIUM NA NA Messenger Cytosol + Opening 2445748
PRKCZ Q05513 Q02956 Kinase Cytosol MAP2K5 Q13163 Q9WVS7 Kinase Cytosol + Phosphorylation 11158308
GRIK1 P39086 Q60934 Channel Membrane SDCBP O00560 O08992 Adapter Cytosol 0 Binding 12597860
GRIK1 P39086 Q60934 Channel Membrane SDCBP O00560 O08992 Adapter Cytosol 0 Binding 11891216
PKIA P61925 P63248 Inhibitor Cytosol PRKACA P17612 P05132 Kinase Cytosol _ Binding 1770951
CTTN Q14247 Q60598 Cytoskeleton Cytosol DNM1 Q05193 P39053 GTPase Vesicles 0 Binding 7680654
CASP3 P42574 P70677 Protease Cytosol PROKR1 Q8TCW9 Q9JKL1 Kinase Cytosol _ Cleavage 11555640
GRIA1 P42261 P23818 Channel Membrane CACNG7 P62955 P62956 Chaperone Cytosol 0 Binding 11140673
GRIA1 P42261 P23818 Channel Membrane CACNG7 P62955 P62956 Chaperone Cytosol 0 Binding 12359873
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol CRK P46108 Q64010 Adapter Cytosol _ Binding 8626404
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol CRK P46108 Q64010 Adapter Cytosol _ Binding 12697763
GLYCINE NA NA Ligand Extracellular GLRA1 P23415 Q64018 Receptor Membrane + Binding 2998565
VTN P04004 P29788 Matrix Extracellular ITGB1 P05556 P09055 CellAdhesion Membrane + Binding 7716514
SNAP25 P60880 P60879 Vesicle Vesicles VAMP1 P23763 Q62442 Vesicle Vesicles 0 Binding 7961655
ABL1 P00519 P00520 Kinase Cytosol GRB2 P62993 Q60631 Adapter Cytosol 0 Binding 8112292
SLC1A3 P43003 P56564 Transporter Membrane GABA NA NA Ligand Extracellular _ Importing 7472524
SLC1A3 P43003 P56564 Transporter Membrane GABA NA NA Ligand Extracellular _ Importing 1975955
GNB2 P62879 P62880 Gprotein Cytosol STX3 Q13277 Q64704 Vesicle Vesicles + Binding 10692440
FRAT2 O75474 Q8K025 Adapter Cytosol GSK3A P49840 NA Kinase Cytosol 0 Binding 11707456
FRAT2 O75474 Q8K025 Adapter Cytosol GSK3A P49840 NA Kinase Cytosol 0 Binding 15073180
JAK2 O60674 Q62120 Kinase Cytosol STAT1 P42224 P42225 TF Nucleus + Phosphorylation 7504784
JAK2 O60674 Q62120 Kinase Cytosol STAT1 P42224 P42225 TF Nucleus + Phosphorylation 7504785
CREB1 P16220 Q01147 TF Nucleus GDNF P39905 P48540 TF Nucleus + Binding 1655749
CAMK2A Q9UQM7 P11798 Kinase Cytosol RPH3A Q9Y2J0 P47708 Vesicle Vesicles + Phosphorylation 7891174
CAMK2A Q9UQM7 P11798 Kinase Cytosol RPH3A Q9Y2J0 P47708 Vesicle Vesicles + Phosphorylation 9425005
MAP3K10 Q02779 NA Kinase Cytosol DLG4 P78352 Q62108 Adapter Cytosol + Binding 11152698
CALM3 P62158 P62204 Activator Cytosol GRM7 Q14831 Q68ED2 Receptor Membrane _ Binding 10488094
CALM3 P62158 P62204 Activator Cytosol GRM7 Q14831 Q68ED2 Receptor Membrane _ Binding 12021391
MAPK14 Q16539 P47811 Kinase Cytosol PLAA Q9Y263 P27612 Phospholipase Cytosol + Phosphorylation 8910365
PRKACA P17612 P05132 Kinase Cytosol AKAP9 Q99996 NA Adapter Cytosol 0 Binding 10390370
PRKACA P17612 P05132 Kinase Cytosol AKAP5 P24588 NA Adapter Cytosol 0 Binding 8599116
PRKACA P17612 P05132 Kinase Cytosol AKAP5 P24588 NA Adapter Cytosol 0 Binding 1512224
TSC1 Q92574 NA GAP Cytosol RHEB Q15382 Q921J2 GTPase Cytosol _ Binding 15809346
TSC1 Q92574 NA GAP Cytosol RHEB Q15382 Q921J2 GTPase Cytosol _ Binding 12820960
TSC1 Q92574 NA GAP Cytosol RHEB Q15382 Q921J2 GTPase Cytosol _ Binding 12842888
TSC1 Q92574 NA GAP Cytosol RHEB Q15382 Q921J2 GTPase Cytosol _ Binding 12869586
HIPK2 Q9H2X6 Q9QZR5 Kinase Cytosol RANBP9 Q96S59 P69566 Adapter Cytosol + Binding 12220523
SRC P12931 P05480 Kinase Cytosol SHC1 P29353 P98083 Adapter Cytosol + Phosphorylation 1409579
SRC P12931 P05480 Kinase Cytosol SHC1 P29353 P98083 Adapter Cytosol + Phosphorylation 10329689
MAP2K5 Q13163 Q9WVS7 Kinase Cytosol MAPK7 Q13164 Q9WVS8 Kinase Cytosol + Phosphorylation 7759517
GLUTAMATE NA NA Ligand Extracellular GRIA1 P42261 P23818 Channel Membrane + Binding 1311100
GLUTAMATE NA NA Ligand Extracellular GRIA1 P42261 P23818 Channel Membrane + Binding 8589990
EFNB2 P52799 P52800 Receptor Membrane DOK1 Q99704 P97465 Adapter Cytosol + Phosphorylation 9233798
CAPZB P47756 P47757 Cytoskeleton Cytosol PIP2 NA NA Lipid Cytosol + Binding 2157283
CAPZB P47756 P47757 Cytoskeleton Cytosol PIP2 NA NA Lipid Cytosol + Binding 9034331
CAPZB P47756 P47757 Cytoskeleton Cytosol PIP2 NA NA Lipid Cytosol + Binding 12052260
RANBP9 Q96S59 P69566 Adapter Cytosol CDC2L1 P21127 P24788 Kinase Cytosol 0 Binding 14511641
ROCK2 O75116 P70336 Kinase Cytosol LIMK1 P53667 P53668 Kinase Cytosol + Phosphorylation 10436159
ROCK2 O75116 P70336 Kinase Cytosol LIMK1 P53667 P53668 Kinase Cytosol + Phosphorylation 10652353
DVL1 O14640 P51141 Adapter Membrane F2R P25116 P30558 Adapter Cytosol + Binding 11433294
DLG1 Q12959 Q811D0 Adapter Cytosol GRIA1 P42261 P23818 Channel Membrane 0 Binding 12070168
PRKACA P17612 P05132 Kinase Cytosol STK24 Q9Y6E0 Q99KH8 Adapter Cytosol + Phosphorylation 10644707
PPP1CC P36873 P63087 Phosphatase Cytosol CAMK2A Q9UQM7 P11798 Kinase Cytosol _ Dephosphorylation 12928489
PPP1CC P36873 P63087 Phosphatase Cytosol CAMK2A Q9UQM7 P11798 Kinase Cytosol _ Dephosphorylation 8753794
MAP3K4 Q9Y6R4 O08648 Kinase Cytosol MINK1 Q8N4C8 Q9JM52 Kinase Cytosol + Phosphorylation 9305639
PICK1 Q9NRD5 Q62083 Adapter Cytosol ARF1 P84077 P84078 GTPase Vesicles 0 Binding 10623590
PPP1CC P36873 P63087 Phosphatase Cytosol RCS NA NA Inhibitor Cytosol _ Dephosphorylation 15499021
DUSP1 P28562 P28563 Phosphatase Cytosol MAPK8 P45983 Q91Y86 Kinase Nucleus _ Dephosphorylation 8626452
DUSP1 P28562 P28563 Phosphatase Cytosol MAPK1 P28482 P63085 Kinase Cytosol _ Dephosphorylation 8626452
DUSP1 P28562 P28563 Phosphatase Cytosol MAPK1 P28482 P63085 Kinase Cytosol _ Dephosphorylation 8221888
EPN2 O95208 Q8CHU3 Adapter Vesicles AP2S1 P53680 P62743 Adapter Vesicles 0 Binding 10336464
CREBBP Q92793 P45481 TF Nucleus PCAF Q92831 NA TF Nucleus + Binding 8945521
EGFR P00533 Q01279 Receptor Membrane WASF1 Q92558 Q8R5H6 Activator Cytosol + Binding 9307968
SRC P12931 P05480 Kinase Cytosol SYK P43405 P48025 Kinase Cytosol + Phosphorylation 7513017
OPRM1 P35372 P42866 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 15082510
AP1B1 Q10567 O35643 Adapter Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 11050117
AP1B1 Q10567 O35643 Adapter Cytosol DNM1 Q05193 P39053 GTPase Vesicles + Binding 10398591
MAPK14 Q16539 P47811 Kinase Cytosol ATF2 P15336 P16951 TF Nucleus + Phosphorylation 8663524
MAPK14 Q16539 P47811 Kinase Cytosol ATF2 P15336 P16951 TF Nucleus + Phosphorylation 12024021
CALCIUM NA NA Messenger Cytosol ADCY5 O95622 P84309 Cyclase Membrane _ Binding 12065575
ACTB P60709 P60710 Cytoskeleton Cytosol FLNA P21333 Q8BTM8 Cytoskeleton Cytosol 0 Binding 325564
PIP2 NA NA Lipid Cytosol RYR1 P21817 NA Channel ER + Binding 1850418
GSN P06396 P13020 Cytoskeleton Cytosol CASP9 P55211 NA Protease Cytosol _ Binding 10660524
ITSN1 Q15811 Q9Z0R4 Adapter Vesicles EPS15 P42566 P42567 Adapter Cytosol 0 Binding 9813051
PPP3R1 P63098 Q63810 Phosphatase Cytosol GABRA1 P14867 P62812 Receptor Membrane + Dephosphorylation 8888004
PPP3R1 P63098 Q63810 Phosphatase Cytosol GABRA1 P14867 P62812 Receptor Membrane + Dephosphorylation 12574411
SIVA O15304 O54926 Adapter Cytosol BCL2L1 Q07817 Q64373 Bcl2Family Mitochondria _ Binding 14739602
PRKACA P17612 P05132 Kinase Cytosol GRM7 Q14831 Q68ED2 Receptor Membrane + Phosphorylation 12021391
PTPN11 Q06124 P35235 Phosphatase Cytosol SPRY1 O43609 Q9QXV9 Adapter Cytosol _ Dephosphorylation 15031289
CERAMIDE NA NA Lipid Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol + Binding 10400653
CALCIUM NA NA Messenger Cytosol PRKCA P17252 P20444 Kinase Cytosol + Binding 438153
ABL1 P00519 P00520 Kinase Cytosol TP53BP1 Q12888 P70399 TF Nucleus + Binding 10629029
MAPK14 Q16539 P47811 Kinase Cytosol RPS6KA5 O75582 Q8C050 Kinase Cytosol + Phosphorylation 9687510
SSTR2 P30874 P30875 Receptor Membrane GNAO1 P09471 P18872 Gprotein Cytosol + Binding 1374909
EPHRIN NA NA Ligand Extracellular EFNB2 P52799 P52800 Receptor Membrane + Binding 12546821
EPHRIN NA NA Ligand Extracellular EFNB2 P52799 P52800 Receptor Membrane + Binding 9233798
PRKCA P17252 P20444 Kinase Cytosol GLRA1 P23415 Q64018 Receptor Membrane _ Phosphorylation 8294452
PRKACA P17612 P05132 Kinase Cytosol BRAF P15056 P28028 Kinase Cytosol + Phosphorylation 10931830
CAMK2A Q9UQM7 P11798 Kinase Cytosol PPP1R9B Q96SB3 Q6R891 Cytoskeleton Cytosol _ Phosphorylation 15228588
SHC1 P29353 P98083 Adapter Cytosol GRB2 P62993 Q60631 Adapter Cytosol 0 Binding 8491186
SHC1 P29353 P98083 Adapter Cytosol GRB2 P62993 Q60631 Adapter Cytosol 0 Binding 9566877
SHC1 P29353 P98083 Adapter Cytosol GRB2 P62993 Q60631 Adapter Cytosol 0 Binding 1465135
SHC1 P29353 P98083 Adapter Cytosol GRB2 P62993 Q60631 Adapter Cytosol 0 Binding 8114695
SHC1 P29353 P98083 Adapter Cytosol GRB2 P62993 Q60631 Adapter Cytosol 0 Binding 8808684
MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol MAPK8 P45983 Q91Y86 Kinase Nucleus _ Binding 9235893
MAPK8IP1 Q9UQF2 Q9WVI9 Adapter Cytosol MAPK8 P45983 Q91Y86 Kinase Nucleus _ Binding 10490659
KCND3 Q9UK17 Q9Z0V1 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 10200233
ADCY5 O95622 P84309 Cyclase Membrane CAMP P49913 P51437 Messenger Cytosol + Synthesis 1618857
RAF1 P04049 Q99N57 Kinase Cytosol BAD Q92934 Q61337 Bcl2Family Mitochondria _ Phosphorylation 8929532
PA NA NA Messenger Cytosol PPP1CC P36873 P63087 Phosphatase Cytosol _ Binding 10409693
VCL P18206 Q64727 Cytoskeleton Cytosol TLN1 Q9Y490 P26039 Cytoskeleton Cytosol 0 Binding 6425696
PTK2B Q14289 Q9QVP9 Kinase Cytosol KCNA2 P16389 P63141 Channel Membrane _ Phosphorylation 7544443
PTK2B Q14289 Q9QVP9 Kinase Cytosol KCNA2 P16389 P63141 Channel Membrane _ Phosphorylation 9560226
STX3 Q13277 Q64704 Vesicle Vesicles CAV1 Q03135 P49817 Adapter Cytosol 0 Binding 11883949
GDNF P39905 P48540 Ligand Extracellular RBP1 P09455 Q00915 Receptor Membrane + Binding 10995764
PIP3 NA NA Lipid Membrane AKT1 P31749 P31750 Kinase Cytosol + Binding 9445477
PRKACA P17612 P05132 Kinase Cytosol CAMKK2 Q96RR4 Q8C078 Kinase Cytosol _ Phosphorylation 10187789
CASP7 P55210 P97864 Protease Cytosol MEF2B Q02080 O55087 TF Nucleus _ Cleavage 11904443
ACE P22966 P22967 Ribosome Ribosomes mRNA NA NA RNA Ribosomes _ Cleavage 8757137
ACE P22966 P22967 Ribosome Ribosomes mRNA NA NA RNA Ribosomes _ Cleavage 9482745
MAPK1 P28482 P63085 Kinase Cytosol RPS6KA5 O75582 Q8C050 Kinase Cytosol + Phosphorylation 9687510
MAPK1 P28482 P63085 Kinase Cytosol RPS6KA1 Q15418 P18653 Kinase Cytosol + Phosphorylation 8202512
MAPK1 P28482 P63085 Kinase Cytosol RPS6KA1 Q15418 P18653 Kinase Cytosol + Phosphorylation 11500364
MAP3K4 Q9Y6R4 O08648 Kinase Cytosol MAP4K3 Q8IVH8 Q99JP0 Kinase Cytosol + Phosphorylation 9305639
PRKG2 Q13237 Q61410 Kinase Cytosol CD38 P28907 P56528 Synthase Cytosol + Phosphorylation 8663443
TIAM1 Q13009 Q60610 GEF Cytosol RAC1 P63000 P63001 GTPase Cytosol + GEF 10212259
ARPC1B O15143 Q9WV32 Cytoskeleton Cytosol ACTB P60709 P60710 Cytoskeleton Cytosol + Binding 9600938
GRM1 Q13255 P97772 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 1847995
GRM1 Q13255 P97772 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 12351712
GRM1 Q13255 P97772 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 1320017
GRM1 Q13255 P97772 Receptor Membrane GNB2 P62879 P62880 Gprotein Cytosol + Binding 1656524
GRM1 Q13255 P97772 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 1847995
GRM1 Q13255 P97772 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 12351712
GRM1 Q13255 P97772 Receptor Membrane GNAQ P50148 P21279 Gprotein Cytosol + Binding 1320017
INSR P06213 P15208 Receptor Membrane IRS2 Q9Y4H2 P81122 Adapter Cytosol + Phosphorylation 7526222
INSR P06213 P15208 Receptor Membrane IRS2 Q9Y4H2 P81122 Adapter Cytosol + Phosphorylation 7675087
INSR P06213 P15208 Receptor Membrane IRS2 Q9Y4H2 P81122 Adapter Cytosol + Phosphorylation 9195949
INSR P06213 P15208 Receptor Membrane IRS1 P35568 P35569 Adapter Cytosol + Phosphorylation 1385403
INSR P06213 P15208 Receptor Membrane IRS1 P35568 P35569 Adapter Cytosol + Phosphorylation 2159922
H2O2 NA NA Messenger Cytosol DSCR1 P53805 Q9JHG6 Inhibitor Cytosol + Binidng 12039863
RGS2 P41220 O08849 Gprotein Cytosol GNAQ P50148 P21279 Gprotein Cytosol _ GAP 14976183
RGS2 P41220 O08849 Gprotein Cytosol GNAQ P50148 P21279 Gprotein Cytosol _ GAP 9736641
STON2 Q8WXE9 Q8BZ60 Adapter Vesicles EPS15L1 Q9UBC2 Q60902 Adapter Cytosol 0 Binding 11381094
SSTR2 P30874 P30875 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 1374909
IHPK2 Q9UHH9 Q80V72 Kinase Cytosol GZMB P10144 P04187 GEF Cytosol 0 Binding 11516400
PPP3R1 P63098 Q63810 Phosphatase Cytosol CAMK4 Q16566 P08414 Kinase Cytosol _ Depolymerization 10085155
PRKCA P17252 P20444 Kinase Cytosol ATP2B1 P20020 NA Pump Membrane _ Phosphorylation 11779484
PRKCA P17252 P20444 Kinase Cytosol ATP2B1 P20020 NA Pump Membrane _ Phosphorylation 9824678
PRKACA P17612 P05132 Kinase Cytosol GLRA1 P23415 Q64018 Receptor Membrane + Phosphorylation 8294452
MAPK1 P28482 P63085 Kinase Cytosol MAPKAPK2 P49137 P49138 Kinase Cytosol + Phosphorylation 1327754
MAPK1 P28482 P63085 Kinase Cytosol MAPKAPK2 P49137 P49138 Kinase Cytosol + Phosphorylation 7592979
PTPRA P18433 P18052 Phosphatase Cytosol LCK P06239 P06240 Kinase Cytosol + Dephosphorylation 9535845
COX5B P10606 P19536 DualRole Mitochondria APAF1 O14727 O88879 Adapter Cytosol + Binding 9267021
COX5B P10606 P19536 DualRole Mitochondria APAF1 O14727 O88879 Adapter Cytosol + Binding 9390557
CAPN1 P07384 O35350 Protease Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Cleavage 11677266
CAPN1 P07384 O35350 Protease Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Cleavage 10846184
CAPN1 P07384 O35350 Protease Cytosol GRIN2A Q12879 P35436 Receptor Membrane _ Cleavage 11553682
GLUTAMATE NA NA Ligand Extracellular GRM7 Q14831 Q68ED2 Receptor Membrane + Binding 10488094
GLUTAMATE NA NA Ligand Extracellular GRM1 Q13255 P97772 Receptor Membrane + Binding 2559758
GLUTAMATE NA NA Ligand Extracellular GRM1 Q13255 P97772 Receptor Membrane + Binding 1656524
IQGAP1 P46940 Q9JKF1 GAP Cytosol RAC1 P63000 P63001 GTPase Cytosol 0 Binding 8798539
IQGAP1 P46940 Q9JKF1 GAP Cytosol RAC1 P63000 P63001 GTPase Cytosol 0 Binding 9199170
DOC2A Q14183 Q7TNF0 Vesicle Vesicles UNC13B O14795 Q9Z1N9 Vesicle Vesicles + Binding 9195900
DOC2A Q14183 Q7TNF0 Vesicle Vesicles UNC13B O14795 Q9Z1N9 Vesicle Vesicles + Binding 9736751
NFKB1 P19838 P25799 TF Nucleus CREBBP Q92793 P45481 TF Nucleus + Binding 9660950
PRKG2 Q13237 Q61410 Kinase Cytosol GRM7 Q14831 Q68ED2 Receptor Membrane + Phosphorylation 12021391
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol LCK P06239 P06240 Kinase Cytosol _ Binding 8083187
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol LCK P06239 P06240 Kinase Cytosol _ Binding 11904433
BAG1 Q99933 Q60739 Adapter Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Binding 12502846
BAG1 Q99933 Q60739 Adapter Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Binding 14978028
BAG1 Q99933 Q60739 Adapter Cytosol RAF1 P04049 Q99N57 Kinase Cytosol + Binding 8692945
DLG4 P78352 Q62108 Adapter Cytosol SRC P12931 P05480 Kinase Cytosol 0 Binding 14529711
PPP2R5C Q13362 Q60996 Phosphatase Cytosol NEFH P12036 P19246 Cytoskeleton Cytosol _ Dephosphorylation 7760048
DOPAMINE NA NA Ligand Extracellular DRD3 P35462 P30728 Receptor Membrane + Binding 15102843
DOPAMINE NA NA Ligand Extracellular DRD2 P14416 P61168 Receptor Membrane + Binding 2898118
DOPAMINE NA NA Ligand Extracellular DRD2 P14416 P61168 Receptor Membrane + Binding 2532362
DOPAMINE NA NA Ligand Extracellular DRD2 P14416 P61168 Receptor Membrane + Binding 2532359
DOPAMINE NA NA Ligand Extracellular DRD1 P21728 Q61616 Receptor Membrane + Binding 2898118
DOPAMINE NA NA Ligand Extracellular DRD1 P21728 Q61616 Receptor Membrane + Binding 2168556
ACH NA NA Ligand Extracellular CHRM4 P08173 P32211 Receptor Membrane + Binding 7916637
ACH NA NA Ligand Extracellular CHRM2 P08172 Q9ERZ4 Receptor Membrane + Binding 3037705
ACH NA NA Ligand Extracellular CHRM2 P08172 Q9ERZ4 Receptor Membrane + Binding 3107123
ACH NA NA Ligand Extracellular CHRM2 P08172 Q9ERZ4 Receptor Membrane + Binding 12799142
ACH NA NA Ligand Extracellular CHRM1 P11229 P12657 Receptor Membrane + Binding 1341877
ACH NA NA Ligand Extracellular CHRM1 P11229 P12657 Receptor Membrane + Binding 12859343
ITSN1 Q15811 Q9Z0R4 Adapter Vesicles CDC42 P60953 P60766 GTPase Cytosol + GEF 11584276
BDKRB1 P46663 Q61125 Receptor Membrane GNAI3 P08754 Q9DC51 Gprotein Cytosol + Binding 11713280
KCNA4 P22459 Q61423 Channel Membrane POTASSIUM NA NA Ion Cytosol + Opening 9437018
ADRBK1 P25098 Q99MK8 Kinase Cytosol OPRM1 P35372 P42866 Receptor Cytosol _ Phosphorylation 10488100
ADRBK1 P25098 Q99MK8 Kinase Cytosol OPRM1 P35372 P42866 Receptor Cytosol _ Phosphorylation 11861651
ABL1 P00519 P00520 Kinase Cytosol DOK1 Q99704 P97465 Adapter Cytosol + Binding 9008161
ABL1 P00519 P00520 Kinase Cytosol DOK1 Q99704 P97465 Adapter Cytosol + Binding 12777393
DLG4 P78352 Q62108 Adapter Cytosol YES1 P07947 Q04736 Kinase Cytosol 0 Binding 14529711
YWHAH Q04917 P68510 Adapter Cytosol CNKSR1 Q969H4 NA Kinase Cytosol 0 Binding 10643560
YWHAH Q04917 P68510 Adapter Cytosol CNKSR1 Q969H4 NA Kinase Cytosol 0 Binding 9115393
PPP3R1 P63098 Q63810 Phosphatase Cytosol CACNA1C Q13936 Q01815 Channel Membrane _ Dephosphorylation 11124974
CALCIUM NA NA Messenger Cytosol RASA4 O43374 NA GAP Cytosol + Binding 11448776
CALCIUM NA NA Messenger Cytosol RASA4 O43374 NA GAP Cytosol + Binding 12845332
CBLB Q13191 Q3TTA7 Ubiquitinase Cytosol VAV1 P15498 P27870 GEF Cytosol _ Ubiquitination 12881521
CAMK1 Q14012 Q91YS8 Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 1646483
GNB2L1 P63244 P68040 Adapter Cytosol SLC9A3R1 O14745 P70441 Adapter Cytosol 0 Binding 11956211
GSK3A P49840 NA Kinase Cytosol CREB1 P16220 Q01147 TF Nucleus + Phosphorylation 7798217
RASA4 O43374 NA GAP Cytosol NRAS P01111 P08556 GTPase Cytosol _ GAP 11448776
RASA4 O43374 NA GAP Cytosol NRAS P01111 P08556 GTPase Cytosol _ GAP 12845332
DNAJC5 Q9H3Z4 P60904 Adapter Cytosol CACNA1B Q00975 O55017 Channel Membrane _ Binding 11086994
DNAJC5 Q9H3Z4 P60904 Adapter Cytosol CACNA1A O00555 P97445 Channel Membrane 0 Binding 9593683