Interaction network and enrichment analysis of genes downregulated following Atorvastatin treatment
Canned Analysis
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General Information
AccessionDCA00033271
TitleInteraction network and enrichment analysis of genes downregulated following Atorvastatin treatment
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Atorvastatin treated cells and untreated control cells in the Peripheral blood monocytes cell type.
Analysis URLhttp://genemania.org/#/search/human/IL7R|LOC728026|IL6|CXCL10|RPL36A|RPL3|GLTSCR2|PTMA|RPL6|CLEC5A|EEF1B2|RPS23|RPS3|RPS27A|RPS20|RPS25|RPS26|PABPC3|NFKBIA|RPS24|RPS27|RPS16|RPL39|TRBC1|RPL30
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curator
CREEDS ID
Cell Type
Drug Name
DrugBank ID
Organism
SMILES ID
Characteristic Direction parameters
Gene Set
Gene Set Size
Control Samples
Perturbed Samples
Tools used in the analysis

Keyword
Dataset Accession

GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis

Keyword
Tool Name

GSE11393
Atorvastatin treatment of familial combined hyperlipidemia: peripheral blood monocytes
28
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