ZNF280B Gene

zinc finger protein 280B

The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015]

znf280b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term znf280b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ZNF280B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ZNF280B from the Pathway Commons Protein-Protein Interactions dataset.