Name

WDR83 Gene

WD repeat domain 83

This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

WDR83OS Gene

WD repeat domain 83 opposite strand

wdr83 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term wdr83 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

WDR83 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for WDR83 from the Pathway Commons Protein-Protein Interactions dataset.

WDR83OS Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for WDR83OS from the Pathway Commons Protein-Protein Interactions dataset.