pre-B lymphocyte 3

The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas. [provided by RefSeq, Apr 2015]

vpreb3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term vpreb3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

VPREB3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for VPREB3 from the Pathway Commons Protein-Protein Interactions dataset.