Name

UQCRB Gene

ubiquinol-cytochrome c reductase binding protein

This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X. [provided by RefSeq, Dec 2011]

UQCRBP2 Gene

ubiquinol-cytochrome c reductase binding protein pseudogene 2

UQCRBP3 Gene

ubiquinol-cytochrome c reductase binding protein pseudogene 3

UQCRBP1 Gene

ubiquinol-cytochrome c reductase binding protein pseudogene 1

uqcrb Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term uqcrb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

UQCRB Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for UQCRB from the Pathway Commons Protein-Protein Interactions dataset.