Name

UBE2E3 Gene

ubiquitin-conjugating enzyme E2E 3

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2013]

ube2e3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ube2e3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

UBE2E3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for UBE2E3 from the Pathway Commons Protein-Protein Interactions dataset.