Name

TRAF3IP2 Gene

TRAF3 interacting protein 2

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq, Aug 2009]

TRAF3IP2-AS1 Gene

TRAF3IP2 antisense RNA 1

traf3ip2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term traf3ip2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TRAF3IP2 Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein TRAF3IP2 from the curated Hub Proteins Protein-Protein Interactions dataset.

TRAF3IP2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TRAF3IP2 from the Pathway Commons Protein-Protein Interactions dataset.

traf3ip2variant Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term traf3ip2variant in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.