Name

TMED7-TICAM2 Gene

TMED7-TICAM2 readthrough

This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. This fusion product functions to negatively regulate the adaptor MyD88-independent toll-like receptor 4 pathway. [provided by RefSeq, Nov 2010]

TMED7 Gene

transmembrane emp24 protein transport domain containing 7

TICAM2 Gene

toll-like receptor adaptor molecule 2

TIRP is a Toll/interleukin-1 receptor (IL1R; MIM 147810) (TIR) domain-containing adaptor protein involved in Toll receptor signaling (see TLR4; MIM 603030).[supplied by OMIM, Apr 2004]

tmed7 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tmed7 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TMED7 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TMED7 from the Pathway Commons Protein-Protein Interactions dataset.

TICAM1-TICAM2-TLR4 complex Gene Set

From CORUM Protein Complexes

proteins in the TICAM1-TICAM2-TLR4 complex protein complex from the CORUM Protein Complexes dataset.

ticam2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ticam2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TICAM2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TICAM2 from the Pathway Commons Protein-Protein Interactions dataset.