Name

THBD Gene

thrombomodulin

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]

thbd Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term thbd in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

THBD Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for THBD from the Pathway Commons Protein-Protein Interactions dataset.