Name

SULF2 Gene

sulfatase 2

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]

sulf2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sulf2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SULF2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SULF2 from the Pathway Commons Protein-Protein Interactions dataset.