Name

STAG3L5P-PVRIG2P-PILRB Gene

STAG3L5P-PVRIG2P-PILRB readthrough

This locus represents naturally occurring readthrough transcription among the neighboring LOC101735302 (stromal antigen 3 pseudogene), LOC101752334 (poliovirus receptor related immunoglobulin domain containing pseudogene) and PILRB (paired immunoglobin-like type 2 receptor beta) genes on chromosome 7. The readthrough transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Jun 2013]

STAG3L5P Gene

stromal antigen 3-like 5 pseudogene

PILRB Gene

paired immunoglobin-like type 2 receptor beta

The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function. [provided by RefSeq, Jun 2013]

PVRIG2P Gene

poliovirus receptor related immunoglobulin domain containing 2, pseudogene

PILRB Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PILRB from the Pathway Commons Protein-Protein Interactions dataset.