RASA3 Gene

RAS p21 protein activator 3

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq, Jul 2008]

RASA3-IT1 Gene

RASA3 intronic transcript 1

RASA3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for RASA3 from the Pathway Commons Protein-Protein Interactions dataset.