Name

PLAGL1 Gene

pleiomorphic adenoma gene-like 1

This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene. [provided by RefSeq, Oct 2010]

plagl1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term plagl1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PLAGL1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PLAGL1 from the Pathway Commons Protein-Protein Interactions dataset.

Zinc finger protein PLAGL1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Zinc finger protein PLAGL1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

SC-22811 (PLAGL1) Gene Set

From NURSA Protein Complexes

proteins in the SC-22811 (PLAGL1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.