Name

PIGA Gene

phosphatidylinositol glycan anchor biosynthesis, class A

This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12. [provided by RefSeq, Jun 2010]

PIGAP1 Gene

phosphatidylinositol glycan anchor biosynthesis, class A, pseudogene 1

piga Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term piga in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PIGA Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for PIGA from the NURSA Protein-Protein Interactions dataset.

PIGA Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PIGA from the Pathway Commons Protein-Protein Interactions dataset.

PIGA, GPI anchor biosynthesis Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the PIGA, GPI anchor biosynthesis protein domain from the InterPro Predicted Protein Domain Annotations dataset.