Name

PDZK1 Gene

PDZ domain containing 1

This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

PDZK1P1 Gene

PDZ domain containing 1 pseudogene 1

PDZK1IP1 Gene

PDZK1 interacting protein 1

pdzk1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdzk1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PDZK1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PDZK1 from the Pathway Commons Protein-Protein Interactions dataset.

PDZK1-NaPiIIa-MAP17 complex Gene Set

From CORUM Protein Complexes

proteins in the PDZK1-NaPiIIa-MAP17 complex protein complex from the CORUM Protein Complexes dataset.

pdzk1ebp50ezrin Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdzk1ebp50ezrin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PDZK1-interacting protein 1 family Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the PDZK1-interacting protein 1 family protein domain from the InterPro Predicted Protein Domain Annotations dataset.

PDZK1IP1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PDZK1IP1 from the Pathway Commons Protein-Protein Interactions dataset.