Name

PDK4 Gene

pyruvate dehydrogenase kinase, isozyme 4

This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq, Jul 2008]

pdk4 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PDK4 Gene Set

From KEA Substrates of Kinases

substrates of the kinase PDK4 from the curated KEA Substrates of Kinases dataset.

PDK4 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PDK4 from the Pathway Commons Protein-Protein Interactions dataset.

PDK4 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase PDK4 from the curated PhosphoSitePlus Substrates of Kinases dataset.