Name

ORC3 Gene

origin recognition complex, subunit 3

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]

orc3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term orc3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ORC3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ORC3 from the Pathway Commons Protein-Protein Interactions dataset.