Name

OGDH Gene

oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]

OGDHL Gene

oxoglutarate dehydrogenase-like

OGDH Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for OGDH from the NURSA Protein-Protein Interactions dataset.

OGDH Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for OGDH from the Pathway Commons Protein-Protein Interactions dataset.

OGDHL Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for OGDHL from the NURSA Protein-Protein Interactions dataset.

OGDHL Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for OGDHL from the Pathway Commons Protein-Protein Interactions dataset.