Name

NRG2 Gene

neuregulin 2

This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010]

nrg2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nrg2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NRG2 Gene Set

From Guide to Pharmacology Protein Ligands of Receptors

receptors of the NRG2 ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

NRG2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NRG2 from the Pathway Commons Protein-Protein Interactions dataset.

nrg2beta Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nrg2beta in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.