Name

NOB1 Gene

NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)

In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010]

nob1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nob1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NOB1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NOB1 from the Pathway Commons Protein-Protein Interactions dataset.

D-site 20S pre-rRNA nuclease Nob1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the D-site 20S pre-rRNA nuclease Nob1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Nin one binding (NOB1) Zn-ribbon-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Nin one binding (NOB1) Zn-ribbon-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.