Name

NLRP12 Gene

NLR family, pyrin domain containing 12

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

nlrp12 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nlrp12 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NLRP12 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NLRP12 from the Pathway Commons Protein-Protein Interactions dataset.

nlrp12nlrp3dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nlrp12nlrp3dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.