Name

LBP Gene

lipopolysaccharide binding protein

The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012]

lbp Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lbp in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

LBP Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for LBP from the Pathway Commons Protein-Protein Interactions dataset.

lbp1b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lbp1b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lbpcd14 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lbpcd14 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lbp32mgr Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lbp32mgr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lbp9 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lbp9 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CP2/LBP-1c/LSF Gene Set

From MotifMap Predicted Transcription Factor Targets

target genes of the CP2/LBP-1c/LSF transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

LBP9 (Tcfcp211) Gene Set

From MotifMap Predicted Transcription Factor Targets

target genes of the LBP9 (Tcfcp211) transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

LBP-1 Gene Set

From MotifMap Predicted Transcription Factor Targets

target genes of the LBP-1 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Transfer of LPS from LBP carrier to CD14 Gene Set

From Reactome Pathways

proteins participating in the Transfer of LPS from LBP carrier to CD14 pathway from the Reactome Pathways dataset.