Name

KDM2A Gene

lysine (K)-specific demethylase 2A

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

kdm2a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term kdm2a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

KDM2A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for KDM2A from the Pathway Commons Protein-Protein Interactions dataset.

BL3632 (KDM2A) Gene Set

From NURSA Protein Complexes

proteins in the BL3632 (KDM2A) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL3631 (KDM2A) Gene Set

From NURSA Protein Complexes

proteins in the BL3631 (KDM2A) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.