inhibin, beta A

The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. [provided by RefSeq, Jul 2008]


INHBA antisense RNA 1

inhba Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term inhba in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

INHBA Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for INHBA from the Pathway Commons Protein-Protein Interactions dataset.