Name

IL5RA Gene

interleukin 5 receptor, alpha

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]

il5ra Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il5ra in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

IL5RA Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for IL5RA from the Pathway Commons Protein-Protein Interactions dataset.

il5ralpha Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il5ralpha in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

il5ra80 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il5ra80 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

il5ra31197ag Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il5ra31197ag in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.