Name

IGFBP7 Gene

insulin-like growth factor binding protein 7

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]

IGFBP7-AS1 Gene

IGFBP7 antisense RNA 1

igfbp7 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term igfbp7 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

IGFBP7 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for IGFBP7 from the Pathway Commons Protein-Protein Interactions dataset.