HOXD12 Gene

homeobox D12

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008]

hoxd12 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hoxd12 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

HOXD12 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for HOXD12 from the Pathway Commons Protein-Protein Interactions dataset.