Name

HMGA2 Gene

high mobility group AT-hook 2

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

hmga2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hmga2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

HMGA2 Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for HMGA2 from the MSigDB Cancer Gene Co-expression Modules dataset.

HMGA2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for HMGA2 from the Pathway Commons Protein-Protein Interactions dataset.

hmga2lpp Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hmga2lpp in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

hmga2mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hmga2mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

hmga2igfbp2nras Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hmga2igfbp2nras in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

hmga2tet1hoxa9 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hmga2tet1hoxa9 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

hmga2targeting Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hmga2targeting in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

HMGA2_KO_GDS5048_26_mouse_embryonic lung Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the HMGA2_KO_GDS5048_26_mouse_embryonic lung gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

HMGA2_KO_GSE55340_21_mouse_lung (E18.5) Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the HMGA2_KO_GSE55340_21_mouse_lung (E18.5) gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.