Name

GRB10 Gene

growth factor receptor-bound protein 10

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]

grb10 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term grb10 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GRB10 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GRB10 from the Pathway Commons Protein-Protein Interactions dataset.

grb1014 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term grb1014 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BL6649 (GRB10) Gene Set

From NURSA Protein Complexes

proteins in the BL6649 (GRB10) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.