Name

GPX1 Gene

glutathione peroxidase 1

This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GPX1P2 Gene

glutathione peroxidase pseudogene 2

GPX1P1 Gene

glutathione peroxidase pseudogene 1

gpx1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gpx1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GPX1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GPX1 from the Pathway Commons Protein-Protein Interactions dataset.

gpx1198ct Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gpx1198ct in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

gpx14 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gpx14 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

gpx1ptp1bpp2a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gpx1ptp1bpp2a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.