Name

GPNMB Gene

glycoprotein (transmembrane) nmb

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

gpnmb Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gpnmb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GPNMB Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GPNMB from the Pathway Commons Protein-Protein Interactions dataset.

gpnmboa Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gpnmboa in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.