FYCO1 Gene

FYVE and coiled-coil domain containing 1

This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq, Dec 2011]

FYCO1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for FYCO1 from the Pathway Commons Protein-Protein Interactions dataset.