Name

FANCL Gene

Fanconi anemia, complementation group L

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

fancl Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term fancl in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

FANCL Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for FANCL from the MSigDB Cancer Gene Co-expression Modules dataset.

FANCL Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for FANCL from the Pathway Commons Protein-Protein Interactions dataset.

Fanconi anemia complex, subunit FancL, WD-repeat containing domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Fanconi anemia complex, subunit FancL, WD-repeat containing domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

E3 ubiquitin-protein ligase FANCL Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the E3 ubiquitin-protein ligase FANCL protein domain from the InterPro Predicted Protein Domain Annotations dataset.