Name

EIF5B Gene

eukaryotic translation initiation factor 5B

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately. [provided by RefSeq, Jul 2008]

EIF5B Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for EIF5B from the NURSA Protein-Protein Interactions dataset.

EIF5B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EIF5B from the Pathway Commons Protein-Protein Interactions dataset.