Name

DEGS1 Gene

delta(4)-desaturase, sphingolipid 1

This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]

degs1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term degs1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

DEGS1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DEGS1 from the Pathway Commons Protein-Protein Interactions dataset.